Molecular Docking and In-Silico Analysis of Natural Biomolecules against Dengue, Ebola, Zika, SARS-CoV-2 Variants of Concern and Monkeypox VirusArticle Published on 2022-09-222022-11-15 Journal: International Journal of Molecular Sciences [Category] SARS, 변종, 진단, 치료제, [키워드] Amino acid AMP AMPs antimicrobial peptide Antiviral antiviral drug Antiviral treatment AutoDock vina B.1.617.2 Bacterial bacterial AMPs binding energy Biomolecule biomolecules Cell cell receptor cell surface receptors concern Control Dengue dengue virus determine develop docking docking score Ebola Ebola virus Effective vaccines envelope protein Evolution in silico increase in indicated Modification molecular molecular docking Monkeypox mutant natural Occurrence P.1 pathogenic viruses positive proline Protein receptors SARS-CoV-2 Secondary Metabolite specific neutralizing antibody tested the SARS-CoV-2 the spike protein therapeutic agents variant variants of SARS-CoV-2 viral cell viral surface virus was performed Zika Zika virus [DOI] 10.3390/ijms231911131 PMC 바로가기
Potent Inactivation of Human Respiratory Viruses Including SARS-CoV-2 by a Photoactivated Self-Cleaning Regenerative Antiviral CoatingArticle Published on 2022-09-142022-11-15 Journal: ACS applied materials & interfaces [Category] SARS, 치료제, [키워드] activity antiviral activity calicivirus circulating coating Complication coronavirus COVID-19 COVID-19 pandemic curtail demonstrated Effect Evidence greatly reduce Health Human implication inactivated Including Novel viruses OC43 pandemic parainfluenza virus Personal protective equipment photoactivated regenerative virucide platform potent progression public health Radiation regenerative resource respiratory rhinovirus RNA SARS-CoV SARS-CoV 2 SARS-CoV-2 self-cleaning surfaces self-sanitizing coating shown Spread TCID Treatment upconversion nanomaterials vaccinia virus vesicular stomatitis virus virucide virus virus transmission viruses Zika virus [DOI] 10.1021/acsami.2c11653 PMC 바로가기
The Antiviral Effects of 2-Deoxy-D-glucose (2-DG), a Dual D-Glucose and D-Mannose Mimetic, against SARS-CoV-2 and Other Highly Pathogenic VirusesArticle Published on 2022-09-122022-11-15 Journal: Molecules [Category] SARS, 유전자 메커니즘, 진단, 치료제, [키워드] 2-deoxy-D-glucose 2-DG Activation Antiviral agents antiviral drug cause Cell change changes changes in coronavirus D-Mannose Effect Glucose Glycolysis glycosylation host cell infected cell Infection Influenza virus inhibitors limit mechanism metabolic shift Mimetic noroviruses novel analogs Other pathway pharmacokinetic reduce respond rhinoviruses SARS-CoV-2 target Therapeutic approach upregulated viral infections Zika virus [DOI] 10.3390/molecules27185928 PMC 바로가기
The choroid plexus and its role in the pathogenesis of neurological infectionsArticle Published on 2022-09-102022-11-15 Journal: Fluids and Barriers of the CNS [Category] SARS, 치료기술, 치료제, [키워드] Activation Alter bidirectional Blood–CSF barrier Borrelia Borrelia burgdorferi Brain Cell cells cellular response Central nervous system cerebrospinal fluid changes in chemotaxis choroid Choroid plexus circulating CNS CNS disorder cytokine dendritic cells develop Diseases disorder driving epithelia epithelial epithelial cell function greater highlight homeostasis homing hydrocephalus Immune cell immune cells immune response Immunity immunological Including induce Infection infections Inflammation inflammatory signal John Cunningham virus junction knowledge less macrophages Neuroinflammation neurological pathogen Pathogenesis Pathogens pharmacological intervention promote provide Research SARS-CoV-2 shown T cells target these cell virus Zika virus [DOI] 10.1186/s12987-022-00372-6 PMC 바로가기
Antiviral efficacy of favipiravir against Zika and SARS-CoV-2 viruses in non-human primates Research Published on 2022-08-302022-10-05 Journal: Nature Communications [Category] SARS, 임상, 치료기술, 치료법, 치료제, [키워드] animal model animal models antiviral activity Clinical efficacy clinical evaluation clinical trial COVID-19 pandemic cynomolgus macaques disease drug Efficacy euthanized evaluate evaluated Evidence Favipiravir High dose implementation in vitro in vitro result Infection initiated no effect non-human primate plasma rapid clinical deterioration RNA virus SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral kinetics SARS-CoV-2 virus statistically significant reduction Support tested translation treated viral kinetics Viral load worsening Zika Zika virus [DOI] 10.1038/s41467-022-32565-w [Article Type] Research
Detection of Zika virus disease in Thiruvananthapuram, Kerala, India 2021 during the second wave of COVID-19 pandemicCOVID-19 전염병의 두 번째 물결 동안 인도 케랄라주 티루바난타푸람에서 지카 바이러스 질병 감지 2021Article Published on 2022-06-012022-09-11 Journal: Journal of medical virology [Category] Fulltext, MERS, 치료기술, [키워드] COVID-19 pandemic detection disease India second wave Zika virus [DOI] 10.1002/jmv.27638 PMC 바로가기 [Article Type] Article
Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogensArticle Published on 2022-05-052023-07-09 Journal: Cell Stem Cell [Category] COVID19(2023년), [키워드] cytotrophoblast extravillous trophoblast naive pluripotency placental development SARS-CoV-2 Single-cell transcriptomics syncytiotrophoblast trophoblast organoids trophoblast stem cells. X chromosome inactivation Zika virus [DOI] 10.1016/j.stem.2022.04.004 PMC 바로가기
Consequences of Viral Infection and Cytokine Production During Pregnancy on Brain Development in OffspringReview Published on 2022-04-072023-07-01 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, [키워드] cortical development Cytokines maternal infections Neurodevelopmental disorders Neuroinflammation SARS – CoV – 2 virus Zika virus [DOI] 10.3389/fimmu.2022.816619 PMC 바로가기 [Article Type] Review
SARS-CoV-2 origin, myths and diagnostic technology developmentsReview Published on 2022-03-042022-11-01 Journal: The Egyptian Journal of Medical Human Genetics [Category] COVID-19, [키워드] accelerated approach assays baseline Body caused China COVID-19 CRISPR Culture Diagnosis diagnostic Diagnostic method diagnostics drug resistance Effect ELISA epidemiological evaluated Factor False negative Future Genome Healthcare systems implication information Intervention isothermal amplification knowledge Laboratory LAMP less management morbidity myth pandemic paucity of data profile provided reducing repeated reported RT-PCR SARS-CoV-2 SARS-CoV-2 virus sensitivity specificity targeted therapy the patient TMA Treatment virus virus genome WHO World Health Organization Zika virus [DOI] 10.1186/s43042-022-00255-3 PMC 바로가기 [Article Type] Review
Neurogenesis and Viral InfectionImmunology Published on 2022-02-172022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, [키워드] Activation acute respiratory syndrome Affect animal models Brain Cell cell cycle progression cell death cells Central nervous system coronavirus cortical disease Evidence extrinsic fetal gliogenesis impairment Infection Invasion Local mammalian nervous system neural stem cell neural stem cells Neurogenesis neurological Neuron neurotropic SARS-CoV-2 stem cell Support Zika virus ZIKV [DOI] 10.3389/fimmu.2022.826091 PMC 바로가기 [Article Type] Immunology