Fighting against the common enemy of COVID-19: a practice of building a community with a shared future for mankindCommentary Published on 2020-04-072022-10-29 Journal: Infectious Diseases of Poverty [Category] COVID-19, SARS, [키워드] acute respiratory syndrome approach caused China Community confirmed case Containment strategy coronavirus coronavirus disease country COVID-19 develop effective effort faster feature Fighting General population hospital Infection International International health regulation Intervention joint MERS-CoV Novel coronavirus outbreak pandemic preparedness Prevent PROTECT Protective public health measure quarantine reported Research resource SARS-CoV SARS-CoV-2 Support the disease Transmissibility Transmission Vaccine development WHO [DOI] 10.1186/s40249-020-00650-1 PMC 바로가기 [Article Type] Commentary
Identification of peptide domains involved in the subcellular localization of the feline coronavirus 3b proteinResearch Article Published on 2019-10-042022-10-30 Journal: The Journal of General Virology [Category] Coronavirus, MERS, [키워드] accessory protein addition amino acid residue Analysis Assessing cell type coronavirus Critical cytoplasmic disease distribution domain downstream ENCODE Evidence Feline coronavirus fluorescent Frame fused identification involved joint less Mitochondria mitochondrial mitochondrial translocation motif mutants N-terminal nuclear localization signal nucleoli Nucleolus ORF3 overlapping peptide Protein residue spatiotemporal subcellular localization transfection [DOI] 10.1099/jgv.0.001321 PMC 바로가기 [Article Type] Research Article
Survey on Implementation of One Health Approach for MERS-CoV Preparedness and Control in Gulf Cooperation Council and Middle East CountriesOnline Report Published on 2019-03-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, Fulltext, MERS, 조류인플루엔자, [키워드] Control cooperation Council country Diseases ENhance Epidemic group Gulf Gulf Cooperation Council Health authority indicated joint Jordan limitation MERS-CoV Middle East Middle East respiratory syndrome Coronavirus mitigate MONITOR one health Policy preparedness and response public health questionnaire respiratory syndrome coronavirus risk Surveillance survey syndrome viruses working zoonoses zoonotic [DOI] 10.3201/eid2503.171702 PMC 바로가기 [Article Type] Online Report
Novel genetic polymorphisms associated with severe malaria and under selective pressure in North-eastern Tanzania심각한 말라리아 및 탄자니아 북동부의 선택적 압력과 관련된 새로운 유전적 다형성Research Article Published on 2018-01-302022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 말라리아, [키워드] acquisition African allele frequencies allele frequency analyses approach association caused Cell characterisation chromosome chromosome 4 Cohort country dataset Endemic Evidence evidence of expected extended haplotype Factors Frequency GCLC gene mutation gene target Genetic genetic factors genetic mutation genetic mutations Genetic polymorphism Genome Genome-wide association studies Genome-wide association study genomes genotyping GWAS haplotypes HbS High-resolution histocompatibility Host Human genome human population human populations identification identify immunological pathways imputation independent Intervention joint KLHL3 linkage loci Major major histocompatibility complex malaria malarial disease mechanism MHC molecular morbidity Mortality natural selection novel parasites performed Phenotypes phenotypic phenotypic variation Plasmodium falciparum Plasmodium falciparum infection polymorphism Population Positive selection Protective Protein Rare variants receptor reduced risk Region Research resulting risk factor selection pressure selective Sequencing severe malaria sickle cell sickle cell trait Significant significant effect SNPs Structural variant structural variants sub-Saharan Africa susceptibility susceptibility loci SYNJ2BP target variant Variation whole genome Whole genome sequencing [DOI] 10.1371/journal.pgen.1007172 PMC 바로가기 [Article Type] Research Article
Public Health Network Structure and Collaboration Effectiveness during the 2015 MERS Outbreak in South Korea: An Institutional Collective Action FrameworkArticle Published on 2017-09-152022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, [키워드] Action Analysis association collaboration collaboration effectiveness collective defined Effect Effectiveness effort framework IMPROVE information institutional collective action framework joint MERS Middle East Middle East Respiratory Syndrome (MERS) coronavirus network organization outbreak positive Public public health public health network Research respiratory risk South South Korea Structure tested [DOI] 10.3390/ijerph14091064 PMC 바로가기 [Article Type] Article
Periodontal Ehlers-Danlos Syndrome Is Caused by Mutations in C1R and C1S , which Encode Subcomponents C1r and C1s of Complement치주 엘러스-단로스 증후군은 보체의 하위 구성요소 C1r 및 C1을 인코딩하는 C1R 및 C1S의 돌연변이로 인해 발생합니다.Article Published on 2016-11-032022-08-07 Journal: American Journal of Human Genetics [Category] 유전자 메커니즘, [키워드] affected attached gingiva autosomal-dominant disorder bruising C1q C1r candidate gene causes characterized childhood classical clinical Clinical features Complement pathway connection connective tissue defined early-onset periodontitis Ehlers-Danlos syndrome Endoplasmic reticulum feature Frame Genetic Gingiva heterotetramer heterozygous homeostasis hyperpigmentation identify include independent individual Inflammatory insertion/deletion International joint joint hypermobility lack locus loss of teeth mapped Mild Missense Musculoskeletal Mutation open periodontal Periodontitis physiological Premature pretibial hyperpigmentation Protein recruited skin subunit subunit interface subunits Symptoms teeth variant Vascular vascular fragility [DOI] 10.1016/j.ajhg.2016.08.019 PMC 바로가기 [Article Type] Article
Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease건강 및 면역 매개 질환의 여러 세포 유형에서 eQTL 매핑을 통한 유전자형-표현형 연관성에 대한 통찰력Research Article Published on 2016-03-252022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Active disease Affect Analysis anti-neutrophil cytoplasmic antibody association Autoimmune Autoimmune diseases blood cell blood vessel blood vessels bowel Cancer cell types cellular cellular activation clinical disease complex complex system contribute cytoplasmic damage database dependent on disease risk disease-associated loci DNA Effect eQTL eQTL analysis eQTL mapping eQTLs estimate examined Examining expression expression data expression quantitative trait loci FIVE Gene Expression Genetic genetic control Genetic studies Genetic variant genetic variants genetics Genome-wide association studies Gut GWAS healthy healthy control healthy controls help Human immune system human inflammatory diseases identifying immune Immune cell immune cell type immune cells immune-mediated diseases in vitro include Infection Inflammation Inflammatory Inflammatory bowel disease inflammatory disease Inflammatory diseases insight investigated joint knowledge leucocyte loci majority mapping Multiple observation Pathogenesis Patient performed proportion PROTECT provide Quantitative regions resulting risk specificity subset subtype tissue tissues Treatment Type variant Vasculitis White blood cell [DOI] 10.1371/journal.pgen.1005908 PMC 바로가기 [Article Type] Research Article
Detection and molecular characterisation of bovine corona and toroviruses from Croatian cattleResearch Article Published on 2015-08-132022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] BCoV bovine BToV carried characterisation coronavirus Croatia detection fecal Fecal sample infections investigated joint molecular nasal Nidovirale nucleocapsid nucleotide Occurrence pathogen Pathogens Phylogenetic analysis Respiratory disease respiratory symptoms Result RT-PCR Sample Sequencing spike Strains submitted Symptom symptomatic synergistic the Coronaviridae virus [DOI] 10.1186/s12917-015-0511-9 PMC 바로가기 [Article Type] Research Article
Extensive Copy-Number Variation of Young Genes across Stickleback Populations스틱백 개체군에 걸친 젊은 유전자의 광범위한 복사 수 변이Research Article Published on 2014-12-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adaptive Analysis candidate Candidates category CNV CNV gene CNV genes CNVs Comparative genomics complexity copy-number variation copy-number variations disparate distribution duplicate gene Duplicate genes duplication duplications eco-genomic model ecological Effect elevated evaluate Evolution Extensive fixed Frequency function functional Genes Genetic genetic diversity Genome highlight identify individual Innovation interactions joint lineage-specific gene lineage-specific genes Local locus low frequencies molecular natural populations occur over Population population genomics population level populations prevalent producing selective pressure selective pressures Stage structural polymorphism subset teleost genome teleost genomes three-spined stickleback three-spined sticklebacks Variation whole genome sequence [DOI] 10.1371/journal.pgen.1004830 PMC 바로가기 [Article Type] Research Article
A Genome-Wide Integrative Genomic Study Localizes Genetic Factors Influencing Antibodies against Epstein-Barr Virus Nuclear Antigen 1 (EBNA-1)게놈 전체에 걸친 통합 게놈 연구는 엡스타인-바 바이러스 핵 항원 1(EBNA-1)에 대한 항체에 영향을 미치는 유전적 요인을 국소화합니다.Research Article Published on 2013-01-102022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] a major Adult adverse outcome adverse outcomes Analysis antibody antibody levels Antigen approach association Author Autoimmune disorders best Burkitt lymphoma Cancer cancers Candidates chromosome chromosome 6 concerning dataset disease Disease progression DQB1 DRB1 EBV Epstein Barr virus Epstein-Barr virus Evidence evidence of examined expression data Factor family members focus foreign antigen foreign antigens found Gene Gene Expression Genetic genetic factors Genome HLA HLA locus HLA-DQB1 HLA-DRB1 Hodgkin lymphoma Host human leukocyte antigen IgG antibodies IgG antibody immune function immune system independent individual infect Infected Infection infectious Infectious disease infectious mononucleosis investigated involved joint leukocyte linkage loci locus lupus erythematosus lymphocyte lymphoproliferative disorders malignancies malignancy measure mechanism MHC class MHC class II multiple sclerosis nasopharyngeal lymphoma not found nuclear overlap P -value pathogen Pathogens prevalent provide regulate related replicated Research severe complication severe complications severe disease significantly SNP SNPs susceptibility susceptibility loci systemic lupus erythematosus T cells virus was obtained [DOI] 10.1371/journal.pgen.1003147 PMC 바로가기 [Article Type] Research Article