SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational burstsSARS-COV-2 변이체 진화 미국에서 : 연쇄 창립자 사건 및 돌연변이 버스트를 통해 시간이 지남에 따라 바이러스 돌연변이의 높은 축적Research Article Published on 2021-07-232022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 변종, 치료기술, [키워드] accumulating additional Spike mutations Amino acid amino acid change amino acid changes B.1.1.7 burst caused Cohort Combination concerning COVID-19 death enzyme Evolution Evolution of SARS-CoV-2 Frequency furin furin cleavage site Genome Glutamine Infection Lineage low frequencies low frequency Mutation mutations nucleotide pandemic pattern predominant Prevalence prominence Protein quartile residue RNA SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-CoV-2 variant sequence sequences single nucleotide variation single nucleotide variations SNVs spike Spike protein Spread summer super-spreader events the SARS-CoV-2 genome the Spike The United States United States vaccine platform variant variants of concern Variation Viral viral genome viral genomes viral isolates viral mutation Wuhan Wuhan, China [DOI] 10.1371/journal.pone.0255169 PMC 바로가기 [Article Type] Research Article
Identification of Potential Binding Sites of Sialic Acids on the RBD Domain of SARS-CoV-2 Spike ProteinChemistry Published on 2021-07-222022-10-31 Journal: Frontiers in Chemistry [Category] COVID-19, [키워드] ACE2 acid acute respiratory syndrome Analysis auxiliary binding binding site caused coronavirus COVID-19 determine DPP4 glycoprotein host cell human cells humans identification Interaction MERS-CoV Middle East molecular pandemic Penetrating Potential predominant probe question RBD RBD domain receptor respiratory SARS-CoV-2 sequence sialic acid Site spike Spike protein SPR the RBD the spike protein virus infection viruses [DOI] 10.3389/fchem.2021.659764 PMC 바로가기 [Article Type] Chemistry
Acute kidney injury Reviews Published on 2021-07-152022-10-05 Journal: Nature Reviews Disease Primers [Category] 바이오마커, 치료제, [키워드] acute kidney AKI Biomarker cause Cell Chronic kidney disease CKD condition consequence Critical care critically ill patients defined Deterioration disease disorder drug Elderly patient hospital identify implementation include Infection Injury invasive kidney kidney dysfunction Kidney function Kidney injury management morbidity nephrotoxic New occur pathophysiological mechanisms poor prognosis predominant regions required Sepsis Shock Support the timing therapy Volume [DOI] 10.1038/s41572-021-00284-z [Article Type] Reviews
The Hierarchy of Walking Needs and the COVID-19 PandemicReview Published on 2021-07-132022-10-30 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] addressed built environment change contribute COVID 19 COVID-19 Cycling Factor FIVE hierarchy hierarchy of walking needs IMPROVE Intervention literature review Mental pandemic predominant reduce Resilience Result seeking sequence significant changes in Stress Transport walking walking behaviour [DOI] 10.3390/ijerph18147461 PMC 바로가기 [Article Type] Review
Cross-sectional analysis of follow-up chest MRI and chest CT scans in patients previously affected by COVID-19COVID-19에 의해 이전에 영향을받은 환자의 후속 흉부 MRI 및 흉부 CT 스캔의 단면 분석Chest Radiology Published on 2021-07-122022-09-01 Journal: La Radiologia Medica [Category] MERS, SARS, 진단, [키워드] abnormality Accuracy affected agreement Analysis Biomarker bronchiolar calculated change Chest Chest computerized tomography Chest CT chest CT scan Chest magnetic resonance imaging chest MRI Computed tomography consolidation coronavirus disease Coronavirus disease 2019 COVID-19 CT scans diagnostic Diagnostic accuracy evaluate evaluated fibrosis Follow-up GGO GGOs Ground-glass opacities ground-glass opacity Inflammation inflammatory activity interlobular septal thickening magnetic resonance imaging material measure MRI Patient Pneumonia positive predominant Result sensitivity specificity vessel [DOI] 10.1007/s11547-021-01390-4 PMC 바로가기 [Article Type] Chest Radiology
Case Report: SARS-CoV-2 as an unexpected causal agent of predominant febrile hepatitisCase Report Published on 2021-07-072022-10-31 Journal: F1000Research [Category] COVID-19, MERS, SARS, [키워드] absence Case report Coronavirus disease 2019 COVID-19 declined demonstrated described diagnosed Diagnosis feature febrile Fever healthy Hepatitis hepatology highlight Hospital admission initial liver Liver injury manifestation medical condition Nasopharyngeal swab Patient PCR PCR testing Pneumonia predominant repeated reported respiratory respiratory symptom returned SARS-CoV-2 SARS-CoV-2 virus Seroconversion Serological testing serology severe COVID-19 Symptom symptoms onset transaminase unique [DOI] 10.12688/f1000research.52929.2 PMC 바로가기 [Article Type] Case Report
Shadow Burden of Undiagnosed Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) on Society: Retrospective and Prospective—In Light of COVID-19Article Published on 2021-07-062022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] aetiology affected affecting Analysis approach assumed assumption burden cause CFS chronic conditions Chronic diseases chronic fatigue syndrome complex Complication consequence Consequences COVID-19 COVID-19 pandemic COVID-19 patient Diagnosis diagnostic disease disorder distress epidemiological Factor fatigue FIVE functional hypothetical impact on society increase increase in induce initial Interaction lack Latvia LIGHT literature review long-lasting ME/CFS myalgic encephalomyelitis Patient patients predict predominant Prevalence Prevent preventive measure problem problems progression Quality of life reduce reported Research severe fatigue severity shadow significantly significantly lower significantly more statistical Study design substantial reduction Symptom Symptoms syndrome Treatment were used [DOI] 10.3390/jcm10143017 PMC 바로가기 [Article Type] Article
Molecular Evolution and Epidemiological Characteristics of SARS COV-2 in (Northwestern) Poland(북서부) 폴란드에서 SARS COV-2의 분자 진화 및 역학 특성Article Published on 2021-07-022022-09-10 Journal: Viruses [Category] SARS, 변종, 유전자 메커니즘, [키워드] accumulated mutation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Analysis analyzed B.1.1.7 B.1.1.7 lineage Bayesian caused circulating clade clades Coronavirus-2 dataset dissemination driven by Epidemics expansion faster followed by Frequency increase in Infection inferences likelihood Lineage Logistic regression Markov chain Maximum likelihood Molecular epidemiology molecular tracing N439K notable outbreak over P681H performed Phylogenetic Phylogeny Poland Population dynamics predominant reflected respiratory responsible SARS-CoV-2 SARS-Cov-2 outbreak in Poland second wave Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus spike mutation Strains substitutions variant virus virus circulation was used whole-genome sequences [DOI] 10.3390/v13071295 PMC 바로가기 [Article Type] Article
Brain imaging in patients with COVID-19: A systematic reviewReview Published on 2021-07-022022-10-28 Journal: Brain, Behavior, & Immunity - Health [Category] COVID-19, [키워드] abnormality acute respiratory syndrome Affect alteration anatomical Brain Brain abnormalities Brain imaging brain regions callosum case control studies case control study Case series Central nervous system cerebral swelling change CNS Cohort studies cohort study conducted coronavirus corpus COVID-19 database Effect Evidence Identified indicate Infection Loss of Smell Methodological quality Neuroimaging Neurological symptom olfactory olfactory brain Patient predominant Region respiratory tract Result resulting SARS-CoV-2 SARS-CoV-2 infected individuals severity Structure structures subcortical systematic review systemic reactions tissue unique was performed zone [DOI] 10.1016/j.bbih.2021.100290 PMC 바로가기 [Article Type] Review
Pathophysiology of Takotsubo Cardiomyopathy: Reopened DebateTakotsubo 심근병증의 병태생리: 재개된 논쟁Review Published on 2021-07-012022-09-11 Journal: Texas Heart Institute journal [Category] SARS, 변종, [키워드] Acetylcholine addition assumed atherosclerotic catecholamine catecholamines/metabolism clinical observations complex Coronary artery Coronary artery disease coronary artery disease/complications coronary spasm coronary vasospasm/complications/physiopathology COVID-19 pandemic debate dominant Effect Effects emotional emotional stress explain feature incidence initial left ventricle manifestation Manifestations mechanism men metabolism modulate Myocardial Myocardial ischemia obstruction Pain pathophysiologic physically plaque plaque, atherosclerotic/physiopathology predominant progressed proof risk Risk factors Sex sex differences spasm spastic Stress Takotsubo cardiomyopathy takotsubo cardiomyopathy/blood/etiology/physiopathology variant ventricular ventricular function, left/drug effects. women [DOI] 10.14503/THIJ-20-7490 PMC 바로가기 [Article Type] Review