RCT – Page 30 – Communicable Diseases Research

Assessment of Studies Evaluating Spinal Manipulative Therapy and Infectious Disease and Immune System Outcomes A Systematic Review

척추 수기 치료 및 감염성 질환 및 면역 체계 결과를 평가하는 연구의 평가 체계적인 검토

Research

Published on 2021-04-132022-09-10
Journal: JAMA Network Open [Category] MERS, SARS, 바이오마커, 임상,

Convalescent Plasma for the Prevention and Treatment of COVID-19: A Systematic Review and Quantitative Analysis

Review

Published on 2021-04-072022-10-31
Journal: JMIR Public Health and Surveillance [Category] COVID-19, MERS,

[키워드] administration adverse events antibodies antibody Antibody titers Antiviral antiviral activity articles benefit Case report Case series Case-control caused Clinical studies clinical study conducted convalescent plasma COVID-19 COVID-19 infection COVID-19 pandemic CP antibody criteria Critically ill data extraction demographics directive Donor dose effective Efficacy eligible Evidence Future generate Guidance heterogeneity identify immunology Immunotherapy in vitro incidence independent item knowledge literature mechanically ventilated Meta-analysis MOST nonrandomized Novel coronavirus objective offer Patient patients with COVID-19 performed plasma poor quality prevention Prophylactic protocols Quality Quantitative Quantitative analysis random-effects model Randomized controlled trial RCT RCTs recommendation reduce mortality reported Reporting Research Result review robust SARS-CoV-2 screening process searched Spread Support supportive care systematic review therapeutic Therapeutic treatment therapy therapy for COVID-19 Treatment viral clearance virus Web of Science
[DOI] 10.2196/25500 PMC 바로가기 [Article Type] Review

Assessment of the Safety and Therapeutic Benefits of Convalescent Plasma in COVID-19 Treatment: A Systematic Review and Meta-Analysis

Medicine

Published on 2021-04-062022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

[키워드] 95% confidence interval administration adverse event adverse events ARMS assessment baseline caused Characteristics clinical trial clinical trials Complete Concomitant medication contributed Controlled trial convalescent plasma coronavirus disease COVID-19 database death defined demographics disease severity effective therapy Effectiveness Efficacy eligibility criteria evaluate Evidence Frequency Health heterogeneity Hospitalization hospitalized COVID-19 patients Intervention item Meta-analysis methodological Mortality mortality rate neutralizing antibody non-randomized trial overall mortality Participants Patient plasma Primary outcome protocol RCT reduce mortality reduced viral load reducing reducing mortality Registered Reporting respiratory retrieved review Safe Safety safety profile SARS-CoV-2 severity significantly suffered the patient Therapeutic approach therapeutic potential therapy transfusion-related adverse events treat treated treated patient Trial trials viral clearance was performed
[DOI] 10.3389/fmed.2021.660688 PMC 바로가기 [Article Type] Medicine

Effects of pomegranate juice ( Punica Granatum ) on inflammatory biomarkers and complete blood count in patients with COVID-19: a structured summary of a study protocol for a randomized clinical trial

COVID-19 환자의 염증성 바이오마커 및 전체 혈구 수에 대한 석류 주스(Punica Granatum)의 효과: 무작위 임상 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2021-04-022022-09-10
Journal: Trials [Category] MERS, SARS, 임상,

[키워드] 1:1 age all the patients anticipated assigned Blinding block block size block sizes blood count C-reactive protein calculated categories CBC Chain Reaction city clinical clinical trial clinical trials Coagulation Coagulopathy comparator complete blood count computer-generated conducted congestive heart failure contraindication control group coronavirus disease Coronavirus disease 2019 COVID COVID-19 criteria CRP Date determined by dinner Discontinuing Disseminated intravascular coagulation dissemination double-blind Effect Efficacy element Enrollment erythrocyte sedimentation erythrocyte sedimentation rate ESR hospital hospitalized patient hospitalized patients ICU IgA IL-6 Immunoglobulin Inflammatory biomarker inflammatory biomarkers Informed consent intensive care intensive care unit interleukin interleukin 6 Intervention intravascular coagulation Iran Juice lactation masking matching placebo Mild mild to moderate moderate name number objective Older Other outcome packaged participant Participation Patient patients performed Placebo placebo-controlled polymerase chain polymerase chain reaction Pomegranate Pomegranate Juice Pregnancy protocol Punica random randomization randomization sequence Randomized randomized clinical trial Randomized controlled trial Randomly RCT real-time polymerase chain reaction Registered Registration registration number researcher RT-PCR Sample Sample size sealed sedimentation rate sequence Sex specialist Standard of care status stratified Study protocol supplementary material the patient total sample size Treatment treatment for COVID-19 Trial Trial registration twice a day Version water website with COVID-19
[DOI] 10.1186/s13063-021-05194-9 PMC 바로가기 [Article Type] Letter

Hydroxychloroquine use and progression or prognosis of COVID-19: a systematic review and meta-analysis

하이드록시클로로퀸 사용과 COVID-19의 진행 또는 예후: 체계적인 검토 및 메타 분석

Meta-Analysis

Published on 2021-04-012022-09-11
Journal: Naunyn-Schmiedeberg's Archives of Pharmacology [Category] 치료제,

[키워드] 95% CI Abstract acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis antiviral activity benefit bioRxiv Chest CT clinical trials Cochrane Library coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 demonstrated eligible Evidence exacerbated HCQ Hydroxychloroquine implicated in vitro inception Inclusion inclusion criteria item Meta-analysis Negative conversion no significant difference no statistical difference participant Patient Pneumonia Prognosis progressed progression RCT RCTs Reporting review robust RT-PCR SARS-CoV-2 screened searched severe acute respiratory syndrome Coronavirus significant difference ST group standard treatment Support systematic review title Treatment treatment for COVID-19 treatment of COVID-19 with COVID-19
[DOI] 10.1007/s00210-020-01964-5 PMC 바로가기 [Article Type] Meta-Analysis

Improving racial disparities in unmet palliative care needs among intensive care unit family members with a needs-targeted app intervention: The ICUconnect randomized clinical trial

Randomized Controlled Trial

Published on 2021-04-012022-10-05
Journal: Contemporary clinical trials [Category] SARS, 임상,

[키워드] Anxiety Arm assist baseline black Black patient Care clinical impact clinical trial clinician concerning Concordance conducted COVID-19 pandemic Critical illness determine EHR Electronic health record Electronic health record (EHR) systems enrolled Health healthcare Hierarchical ICU ICU Patients ICUs Improving include intensive care intensive care units interaction term Intervention intervention effect Linear model manuscript Mobile Mobile App outcome palliative Palliative care parallel group participant physician Post-traumatic stress disorder Primary outcome Psychological distress Racial Racial health disparities Randomized randomized clinical trial Randomized clinical trial (RCT). RCT receive reduce reducing remained resource secondary symptoms of depression their family members treat Two-arm usual care white
[DOI] 10.1016/j.cct.2021.106319 PMC 바로가기 [Article Type] Randomized Controlled Trial

Folic acid as placebo in controlled clinical trials of hydroxychloroquine prophylaxis in COVID-19: Is it scientifically justifiable?

COVID-19에서 하이드록시클로로퀸 예방에 대한 통제된 임상 시험에서 위약으로서의 엽산: 과학적으로 정당화될 수 있습니까?

Article

Published on 2021-04-012022-08-31
Journal: Medical Hypotheses [Category] MERS, 임상, 치료제,

Prophylaxis for COVID-19: a systematic review

COVID-19 예방: 체계적인 검토

Article

Published on 2021-04-012022-09-11
Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 비임상, 임상, 진단, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 animals antibodies breath candidate Candidates clinical clinical trial registry Committee controlled trials coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cross-sectional studies cross-sectional study database eligibility criteria evaluated Evidence FIVE HCQ Human Hydroxychloroquine identify inclusion criteria journal landscape majority medRxiv Novel coronavirus novel coronavirus disease other compounds outcome populations PrEP Prophylactic Prophylaxis Randomized control trials Randomized controlled trial RCT RCTs registries registry reported respiratory SARS-CoV-2 systematic review Treatment Vaccine Vaccines Vitamin vitamins while
[DOI] 10.1016/j.cmi.2021.01.013 PMC 바로가기 [Article Type] Article

Efficacy and safety outcomes of proposed randomized controlled trials investigating hydroxychloroquine and chloroquine during the early stages of the COVID-19 pandemic

COVID-19 전염병의 초기 단계에서 하이드록시클로로퀸과 클로로퀸을 조사하는 제안된 무작위 대조 시험의 효능 및 안전성 결과

Review

Published on 2021-04-012022-09-11
Journal: British Journal of Clinical Pharmacology [Category] 임상, 치료제,

[키워드] accounted adverse events approach Chloroquine clinical Clinical improvement Clinical outcome Clinical practice clinical trials Combination COVID-19 COVID-19 pandemic database diagnosed with COVID-19 domain early stage early stages Efficacy evaluate Final Health Organization heterogeneous Hydroxychloroquine interquartile interquartile range median Mortality other treatment other treatments outcome outcome measure outcomes pandemic Patient patients with COVID-19 primary clinical outcome primary endpoints randomized clinical trial Randomized controlled trial RCT RCTs Registered registry Regulatory reported Research Sample size searched Serious Adverse Events translate Treatment Trial unique was performed World Health Organization
[DOI] 10.1111/bcp.14598 PMC 바로가기 [Article Type] Review

Comparison of Knowledge and Information-Seeking Behavior After General COVID-19 Public Health Messages and Messages Tailored for Black and Latinx Communities : A Randomized Controlled Trial

Randomized Controlled Trial

Published on 2021-04-012022-10-05
Journal: Annals of internal medicine [Category] SARS, 임상,