severe cases – Page 30 – Communicable Diseases Research

Physiology of Midkine and Its Potential Pathophysiological Role in COVID-19

Physiology

Published on 2020-12-222022-10-31
Journal: Frontiers in Physiology [Category] COVID-19,

Increased expression of hypoxia-induced factor 1α mRNA and its related genes in myeloid blood cells from critically ill COVID-19 patients

Research Article

Published on 2020-12-212022-10-28
Journal: Annals of Medicine [Category] COVID-19,

[키워드] blood cell bronchoalveolar Cell cells cellular cellular response characterized clinical manifestations COVID-19 COVID-19 patient COVID-19 severity Critically ill CXCL8 CXCR1 CXCR2 event events explain Express expressed expression FIVE GAPDH Genes HIF1α hypoxia immature immature myeloid cells Immunopathogenesis Increased Inflammation involved leukocyte lung cell marker metabolism molecular monocyte monocyte-macrophages Monocytes mRNA myeloid cell Neutrophils oxygen levels performed peripheral blood cells PFKFB3 PGK1 physiological response potential molecular precursors regulated Result RNAseq SARS-CoV-2 scRNAseq severe cases SLC2A3 SOD2 subset target targets therapy TLR TLR2 transcription factor transcriptional transcriptionally virus
[DOI] 10.1080/07853890.2020.1858234 PMC 바로가기 [Article Type] Research Article

Modeling the Effects of Nonpharmaceutical Interventions on COVID-19 Spread in Kenya

Research Article

Published on 2020-12-182022-10-29
Journal: Interdisciplinary Perspectives on Infectious Diseases [Category] COVID-19,

[키워드] approach basic reproduction number coronavirus disease country COVID-19 Critical Effect expressed fatality Hospitalized implementation infections Intervention Kenya modeling nonpharmaceutical intervention NPI NPIs pandemic partial lockdown predicted resulting Runge–Kutta methods SEIR severe cases
[DOI] 10.1155/2020/6231461 PMC 바로가기 [Article Type] Research Article

Favorable outcome of COVID-19 in a young woman with severe Crohn’s disease on regular use of adalimumab and prednisone: a case report

아달리무맙과 프레드니손을 정기적으로 사용했을 때 중증 크론병을 앓고 있는 젊은 여성의 코로나19 긍정적인 결과: 증례 보고

Case Reports

Published on 2020-12-182022-09-12
Journal: Revista do Instituto de Medicina Tropical de São [Category] MERS, 진단,

Psychiatry during the Covid-19 pandemic: a survey on mental health departments in Italy

Research Article

Published on 2020-12-162022-10-27
Journal: BMC Psychiatry [Category] Coronavirus, COVID-19, MERS, SARS,

[키워드] activities activity Admission aggressiveness Analysis Care carried Community conducted consequence Contact COVID COVID-19 Department drastic reduction Emergency Epidemic expected Fisher Exact functioning head increase in Inpatient introduced Italian Italy mental health Mental health departments mental health service online questionnaire pandemic Pandemics Patient patients Personal protective equipment PPE problem Psychiatric psychiatric assistance Questionnaires reduced Registered remote reported response restrictions Result returned severe cases Significant square supplementary material Swab symptomatic Treatment unit ward Yates correction
[DOI] 10.1186/s12888-020-02997-z PMC 바로가기 [Article Type] Research Article

Psychiatry during the Covid-19 pandemic: a survey on mental health departments in Italy

Research Article

Published on 2020-12-162022-10-27
Journal: BMC Psychiatry [Category] COVID-19,

[키워드] activities activity Admission aggressiveness Analysis Care carried Community conducted consequence Contact COVID COVID-19 Department drastic reduction Emergency Epidemic expected Fisher Exact functioning head increase in Inpatient introduced Italian Italy mental health Mental health departments mental health service online questionnaire pandemic Pandemics Patient patients Personal protective equipment PPE problem Psychiatric psychiatric assistance Questionnaires reduced Registered remote reported response restrictions Result returned severe cases Significant square supplementary material Swab symptomatic Treatment unit ward Yates correction
[DOI] 10.1186/s12888-020-02997-z PMC 바로가기 [Article Type] Research Article

Evolution of COVID-19 in patients with autoimmune rheumatic diseases

Research Paper

Published on 2020-12-152022-10-28
Journal: Aging (Albany NY) [Category] COVID-19, MERS, SARS,

[키워드] analyzed ARDS Autoimmune Autoimmune rheumatic diseases caused Characteristics Comorbidity confirmed case Coronavirus disease 2019 Course COVID-19 COVID-19 in patient COVID-19 patient critical cases Critical disease Diseases electronic medical record feature General population higher risk Hospital stay Huoshenshan Hospital ICU admission immune defense immunological immunosuppressive agent laboratory feature less Manifestations Mortality Patient patients proportion reported Retrospective study rheumatic disease rheumatoid arthritis risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus severe cases SLE SPSS suppressed susceptibility systematic lupus erythematosus the cytokine storm
[DOI] 10.18632/aging.202193 PMC 바로가기 [Article Type] Research Paper

Challenges and Opportunities from Targeting Inflammatory Responses to SARS-CoV-2 Infection: A Narrative Review

Review

Published on 2020-12-122022-10-30
Journal: Journal of Clinical Medicine [Category] COVID-19,

[키워드] “cytokine storm” acute respiratory syndrome Anti-inflammatory anti-inflammatory drug Anti-inflammatory drugs anti-viral drug approach benefit Care challenge clinical care Clinical practice clinical trial clinician complementary condition Coronavirus-2 COVID-19 COVID-19 disease COVID-19 patient Cytokine storm develop disease severity drug early stage effective effective therapy effort Evidence expected global pandemic Host Hypothesis immune defense immunomodulation immunomodulatory activities Infection Inflammation Inflammatory introduced management morbidity and mortality narrative novel coronavirus disease opportunity patients pro-inflammatory cytokine Replication Research response review risk Safe SARS-CoV-2 SARS-CoV-2 entry severe cases Spread targeting the disease therapy Vaccines virus while worsening
[DOI] 10.3390/jcm9124021 PMC 바로가기 [Article Type] Review

SARS-CoV-2: Immune Response Elicited by Infection and Development of Vaccines and Treatments

SARS-CoV-2: 감염 및 백신 및 치료제 개발로 유발되는 면역 반응

Review

Published on 2020-12-112022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료기술, 치료제,

[키워드] acute respiratory syndrome coronavirus addition administration affected antiparasitic antivirals approach approved caused characterized clinical clinical evidence clinical manifestation clinical manifestations Clinical stages clinical trial clinical trials contribute convalescent serum coronavirus coronavirus 2 coronavirus disease COVID-19 COVID-19 disease current therapy deaths described development disease distress drug dry cough effective Evidence exacerbated FDA Fever food Food and Drug Administration headache Health Organization Human Hydroxychloroquine immune Immune cell immune cells immune response immunological imperative Infection Infectious disease information mediators Migration monoclonal antibody monoclonal antibody therapy neutralize organ pandemic Phase III clinical trials potential therapy Prevent proinflammatory mediator proinflammatory mediators respiratory respiratory distress response SARS-CoV-2 SARS-CoV-2 patients severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Severe case severe cases Symptom tested therapy Treatment treatments Vaccine vaccine candidate Vaccines virus WHO World Health Organization
[DOI] 10.3389/fimmu.2020.569760 PMC 바로가기 [Article Type] Review

Serum neopterin levels in relation to mild and severe COVID-19

경증 및 중증 COVID-19와 관련된 혈청 네오프테린 수치

Comparative Study

Published on 2020-12-102022-09-10
Journal: BMC Infectious Diseases [Category] MERS, SARS, 바이오마커,

[키워드] can be used caused clinic clinician Concentration coronavirus coronavirus SARS-CoV-2 Course COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients disease elevated help Hospitalization identify immune activation Inclusion information initial intensive care Kynurenine marker mean value Mild Mild disease Mild symptom mild symptoms Neopterin Patient patients with SARS poor prognosis Prognostic marker Prognostic markers Prognostic value Result serum serum levels Severe case severe cases severe COVID-19 severely ill patient severely ill patients severity of COVID-19 shown Tryptophan were measured with mild disease
[DOI] 10.1186/s12879-020-05671-7 PMC 바로가기 [Article Type] Comparative Study