Case Report: A Recovered SARS CoV-2 Patient Protected From ReinfectionMedicine Published on 2020-09-252022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Case report caused clinical trials COVID-19 pandemic diagnosed effective Evidence Health Healthcare provider herd immunity individuals Patient protection recovered recovered patient Reinfection Research SARS CoV-2 Saudi Arabia seeking Treatment Vaccine Vaccines virus [DOI] 10.3389/fmed.2020.564264 PMC 바로가기 [Article Type] Medicine
Animal Models for COVID-19: More to the Picture Than ACE2, Rodents, Ferrets, and Non-human Primates. A Case for Porcine Respiratory Coronavirus and the Obese Ossabaw PigMicrobiology Published on 2020-09-252022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] ACE2 ACE2 protein angiotensin-converting enzyme 2 animal animal model bind binding cardiovascular disease caused Comorbidity COVID COVID-19 COVID-19 pandemic COVID-19 patient Critically ill determine diabetes diagnostics disease Express healthy hospitals host cell receptor Infection infection with SARS-CoV-2 investigated majority mechanism metabolic syndrome Mild Model MOST Non-human non-human primates obese obesity occur occurred Ossabaw pig outcome pig primates Research respiratory Respiratory Coronavirus rodents SARS-CoV-2 severe COVID-19 Spike protein susceptible syndrome transgenic Vaccines viral spike protein virus [DOI] 10.3389/fmicb.2020.573756 PMC 바로가기 [Article Type] Microbiology
Implications of human activities for (re)emerging infectious diseases, including COVID-19Review Published on 2020-09-252022-10-30 Journal: Journal of Physiological Anthropology [Category] COVID-19, SARS, [키워드] (Re)emerging infectious disease activity coronavirus COVID-19 diagnostics disease Diseases effective emerging disease Epidemics Factor Factors Health humans Impact Infectious disease Occurrence pandemic pathogen reduce respond risk Spread Surveillance threat Transmission Vaccines [DOI] 10.1186/s40101-020-00239-5 PMC 바로가기 [Article Type] Review
The Coronaviruses of Animals and Birds: Their Zoonosis, Vaccines, and Models for SARS-CoV and SARS-CoV2Veterinary Science Published on 2020-09-242022-11-01 Journal: Frontiers in Veterinary Science [Category] COVID-19, [키워드] accumulated addition addressed animal animal model BCoV bovine canine carried contribute coronavirus Coronaviruses determinant Diseases effective vaccine effort Factor family Coronaviridae FCoV human coronavirus implementation mammal MERS-CoV Model mutations New coronavirus Pathogenesis proceed quasispecy raising RNA viruses SARS-CoV SARS-CoV-2 SARS-CoV2 Treatment Trial Vaccine Vaccine development Vaccines virus zoonosis zoonotic disease [DOI] 10.3389/fvets.2020.582287 PMC 바로가기 [Article Type] Veterinary Science
Possible Cross-Reactivity between SARS-CoV-2 Proteins, CRM197 and Proteins in Pneumococcal Vaccines May Protect Against Symptomatic SARS-CoV-2 Disease and DeathArticle Published on 2020-09-242022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Against Antigen BCG capsular polysaccharides composed COVID-19 criteria CRM197 cross-reactive cross-reactivity death diphtheria–tetanus–pertussis Effectiveness equivalent glycosylation Haemophilus influenzae highly antigenic human clinical trial measles–mumps–rubella membrane protein Meningitis meningococcus mumps pneumococcal Poliovirus polysaccharide structure PROTECT protection Protein PsaA PspA PspC SARS-CoV-2 SARS-CoV-2 antigens SARS-CoV-2 disease SARS-COV-2 infection SARS-CoV-2 protein similarities similarity Streptococcus pneumoniae Structure surface protein symptomatic case the spike protein vaccination Vaccine Vaccines [DOI] 10.3390/vaccines8040559 PMC 바로가기 [Article Type] Article
Sequence analysis of SARS-CoV-2 genome reveals features important for vaccine designArticle Published on 2020-09-242022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] Analysis approach Biotechnology codon usage Computational biology and bioinformatics Critical effective feature frameshift generate genome sequence genomic sequence Human genome human tissue in silico knowledge lung nucleocapsid pandemic performed Protein question reveal RNA SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 vaccine target the SARS-CoV-2 Transcriptome Vaccine Vaccine design Vaccine development Vaccines virus viruses [DOI] 10.1038/s41598-020-72533-2 PMC 바로가기 [Article Type] Article
Cross-Protection against MERS-CoV by Prime-Boost Vaccination Using Viral Spike DNA and ProteinVaccines and Antiviral Agents Published on 2020-09-232022-10-30 Journal: Journal of Virology [Category] COVID-19, [키워드] addition amino acids binding cause cell-mediated immune response Cellular immune response cellular receptor Combination Coronavirus vaccines Coronaviruses cross-neutralization cross-protection cross-protective demonstrated develop DNA DNA plasmid DNA viruses effective examined expected Heterologous high mortality human DPP4 humoral immunization immunized immunized mice induce interferon MERS-CoV mice Middle East mouse Mutation Neutralizing antibodies neutralizing antibody platform priming promote Protein provided RBD Recombinant protein regimen respiratory syndrome coronavirus RNA virus S-protein S-pseudovirion sequence sera severe respiratory illness spike spike glycoprotein strain subunit suggested the receptor-binding domain vaccination Vaccine Vaccine development Vaccines variant viral infection viral strain viruses wild-type [DOI] 10.1128/JVI.01176-20 PMC 바로가기 [Article Type] Vaccines and Antiviral Agents
High-throughput viral microneutralization method for feline coronavirus using image cytometryArticle Published on 2020-09-232022-11-01 Journal: Journal of virological methods [Category] Coronavirus, MERS, [키워드] absence accelerate addition antibodies antigenicity Antiviral compounds antiviral drug approved assays Asymptomatic automatically buffer Celigo Cell characterized clinical conditions Concentration coronavirus Coronavirus infection cytolytic cytometer Cytometry death Effects faster fatal disease Feline coronavirus (FCoV) fluorescent generate high-throughput screening (HTS) Image Image cytometry immune correlate immune response Infection labeling majority microneutralization mutate performed plaque reduction neutralization Plaque-Reduction neutralization tests (PRNT) plaques plasma populations Prevent PRNT Protein provide quantification reducing robust sensitivity serotype therapeutic time-consuming treat type I Vaccine vaccine candidate Vaccines Variation viral burden viral infectious disease viral neutralization viral titer virus virus-infected cell was used wash buffer [DOI] 10.1016/j.jviromet.2020.113979 PMC 바로가기 [Article Type] Article
Geriatric Population During the COVID-19 Pandemic: Problems, Considerations, Exigencies, and BeyondPublic Health Published on 2020-09-222022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome age clinical manifestations confirmed case coronavirus coronavirus disease COVID-19 death decrease determine disease disease control disease severity expression Factor Geriatrics hidden immune function Immunity implementation increased mortality Infection Measures Mortality Older older people organ function pandemic pathophysiologic personal health poor health Population prevention preventive measure Probability PROTECT receptor response resulting risk SARS-CoV-2 severe COVID-19 severity susceptibility Symptom treating COVID-19 underlying disease underlying diseases Vaccine design Vaccines Variation [DOI] 10.3389/fpubh.2020.574198 PMC 바로가기 [Article Type] Public Health
Impact of COVID-19 on Immunization Services for Maternal and Infant Vaccines: Results of a Survey Conducted by Imprint—The Immunising Pregnant Women and Infants NetworkArticle Published on 2020-09-222022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] access Analysis caused clinician country COVID-19 COVID-19 pandemic global health Health Service Healthcare provider healthcare service immunization Impact IMPRINT Infant Local majority Maternal maternal immunization Neonatal network pandemic parent Qualitative quantification question questionnaire reported response Result service Support survey vaccination Vaccine Vaccines [DOI] 10.3390/vaccines8030556 PMC 바로가기 [Article Type] Article