muLTi-Arm Therapeutic study in pre-ICu patients admitted with Covid-19-Experimental drugs and mechanisms (TACTIC-E): A structured summary of a study protocol for a randomized controlled trial
코비드-19-실험 약물 및 기전(TACTIC-E)으로 입원한 ICu 전 환자에 대한 다중 암 치료 연구: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약
Letter
[키워드] able to swallow
adaptive
Adaptive trial
added
Admission
age
Ambrisentan
Analysis
approved
Arm
ARMS
balloon pump
balloon pump)
baseline
benefit
Biomarker
blinded
Blinding
calculated
Cambridge
Cambridge University Hospitals NHS Foundation Trust
can not
cardiac
cardiovascular complications
cells
clearance
clinical endpoint
Clinical endpoints
clinical picture
clinically
Combination
comparator
comparison
Complete
Composite
Course
COVID-19
COVID-19 infection
creatinine
creatinine clearance
CRP
Dapagliflozin
Data analysis
Day
death
defined
demonstrated
determine
diabetes
Diagnosis
discretion
disease
dissemination
drug
drugs
ECMO
EDP1815
Efficacy
element
enrolled
envelope
EU Clinical Trial
EU Clinical Trials
EudraCT
Evidence
evidence of
exclusion criteria
Experimental drugs
failure
feature
fixed
foundation
Gault
Gender
group
hypertension
immunomodulation
immunomodulatory
incidence
include
Inclusion
independent
independent data monitoring committee
Inotropes
Intervention
Invasive mechanical ventilation
investigator
Laboratory
late stage
male
mechanism
membrane
neutrophil
Neutrophils
NHS
number
objective
Occurrence
on admission
once daily
Open-label
open-label trial
opinion
option
Organ failure
organ support
Other
outcome
Oxygenation
pandemic
Parallel Arm
participant
Patient
patients with COVID-19
performed
phase
platform
Platform trial
positive
positive COVID-19
predicted
Primary outcome
principal investigator
progression
protocol
Radiographic
radiological
randomisation
randomised
Randomized controlled trial
recruited
reduce
Registered
related disease
renal
renal failure
risk
Sample size
severity
Standard of care
status
stratified
Study protocol
subject
Support
tablets
the patient
therapy
Treatment
treatment arm
Trial
Trial registration
triggered
Trust
university
website
[DOI] 10.1186/s13063-020-04618-2 PMC 바로가기 [Article Type] Letter
[DOI] 10.1186/s13063-020-04618-2 PMC 바로가기 [Article Type] Letter