Risk factors for mortality in hospitalized patients with COVID-19 from three hospitals in Peru: a retrospective cohort studyResearch Article Published on 2021-03-192022-10-31 Journal: F1000Research [Category] COVID-19, SARS, [키워드] 95% CI 95% confidence interval adjusted Admission Adults age average calculated Care carried cohort study Comorbidity country COVID-19 diagnosis of COVID-19 evaluate evaluated Factor first stage functions group hazard hospital Hospitalized hospitalized patient laboratory parameter Latin America less male Mortality Older oxygen saturation pandemic patients hospitalized reduce mortality regression analysis retrospective cohort study risk risk factor SARS-CoV-2 Sociodemographic Symptom Symptoms the mean Treatment variables with COVID-19 [DOI] 10.12688/f1000research.51474.1 PMC 바로가기 [Article Type] Research Article
COVID-19-induced granulomatosis with polyangiitis다발혈관염을 동반한 코로나19 유발 육아종증Case Reports Published on 2021-03-182022-09-12 Journal: BMJ case reports [Category] SARS, 진단, [키워드] antibodies antibody Case report clinician COVID-19 cytoplasmic diagnosed diagnosed with COVID-19 elevated fatigue functions Infectious diseases Patient radiological features renal renal medicine Respiratory medicine rheumatology Shortness of breath worsening [DOI] 10.1136/bcr-2021-242142 PMC 바로가기 [Article Type] Case Reports
Telerehabilitation Intervention in Patients with COVID-19 after Hospital Discharge to Improve Functional Capacity and Quality of Life. Study Protocol for a Multicenter Randomized Clinical Trial퇴원 후 COVID-19 환자의 기능적 능력과 삶의 질 향상을 위한 원격 재활 중재. 다기관 무작위 임상 시험을 위한 연구 프로토콜Study Protocol Published on 2021-03-122022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 임상, [키워드] blind Capacity Care carried clinical clinical trial complementary confinement Consequences COVID-19 COVID-19 sequelae discharge discharge from hospital disease Dyspnea Effectiveness evaluate Evidence function functional functional capacity functions Health Health Education health system hospital hospital discharge Hypothesis identify implementation Intervention life multicenter Patient Perception Perspective Physiotherapy Program Quality Quality of life randomized clinical trial rehabilitation rehabilitation center Research respiratory Respiratory system Satisfaction Secondary objectives South Spain strength Study protocol telerehabilitation to define Treatment treatment method with COVID-19 [DOI] 10.3390/ijerph18062924 PMC 바로가기 [Article Type] Study Protocol
Neurological symptoms in COVID-19: a cross-sectional monocentric study of hospitalized patientsResearch Article Published on 2021-03-122022-10-30 Journal: Neurological Research and Practice [Category] COVID-19, [키워드] Aachen abnormality affected Analysis ARDS assessment Brain caused cerebrospinal fluid Clinical characteristics cognitive deficit Cognitive impairment Complication complications of COVID-19 COVID-19 Critically ill cross-sectional CSF determine evaluated Evidence executive feasible feature functions Future Germany headache Hospitalized hospitalized COVID-19 patient hospitalized patient Hyposmia Invasion Laboratory Longitudinal assessment Major memory Montreal Neuro-invasive potential neurological Neurological deficit neurological manifestation neurological manifestations Neurological symptom Neurological symptoms nine non-critically ill patient olfactory Pain Patient patients patients with ARDS PCR polymerase chain positive positive SARS-CoV-2 PCR pro-inflammatory pulmonary symptoms radiological recall reported required respiratory Respiratory system responsible Result SARS-CoV-2 SARS-COV-2 infection stroke supplementary material Symptoms Test university virus weakness [DOI] 10.1186/s42466-021-00116-1 PMC 바로가기 [Article Type] Research Article
Skeletal Muscle Wasting and Function Impairment in Intensive Care Patients With Severe COVID-19Physiology Published on 2021-03-112022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] absence Admission Brazil Care classification COVID-19 Critical disease Critically ill patient cross-sectional area develop Diagnosis disability evaluate function functional functionality functions handgrip strength ICF ICU impairment IMS intensive care intensive care patient intermedius limb magnitude muscle Muscle strength Muscle wasting occurred Older parameter Patient performed quadricep recruited reductions in remained Respiratory function Respiratory system returned RT-PCR SARS-CoV-2 (2019-nCoV) severe COVID-19 Skeletal muscle the patient Ultrasound vastus was determined wasting [DOI] 10.3389/fphys.2021.640973 PMC 바로가기 [Article Type] Physiology
Structure, Dynamics, Receptor Binding, and Antibody Binding of the Fully Glycosylated Full-Length SARS-CoV-2 Spike Protein in a Viral Membrane바이러스 막에서 완전히 당화된 전체 길이 SARS-CoV-2 스파이크 단백질의 구조, 역학, 수용체 결합 및 항체 결합Article Published on 2021-03-102022-09-12 Journal: Journal of chemical theory and computation [Category] MERS, SARS, 진단, [키워드] ACE2 ACE2 binding acute respiratory syndrome Analysis angiotensin-converting enzyme 2 antibodies antibody epitope antiviral therapeutics binding competent composed conformation coronavirus Dynamics effective flexible full-length SARS-CoV-2 functions glycan glycosylated host cell identify independent Interaction joint Molecular dynamics simulation observation offer performed Protein RBD S protein SARS-CoV-2 shielding spike Structure the RBD the receptor-binding domain the SARS-CoV-2 Vaccine development viral membrane [DOI] 10.1021/acs.jctc.0c01144 PMC 바로가기 [Article Type] Article
Anti-Infective, Anti-Inflammatory, and Immunomodulatory Properties of Breast Milk Factors for the Protection of Infants in the Pandemic From COVID-19COVID-19로부터 팬데믹에 있는 유아를 보호하기 위한 모유 인자의 항감염, 항염 및 면역 조절 특성Public Health Published on 2021-03-022022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 치료제, [키워드] Anti-inflammatory Antiviral antiviral activity Breast breast milk clinical application of human milk factors component components coronavirus disease Coronavirus disease 2019 COVID COVID 19 COVID-19 COVID-19 disease COVID-19 pandemic Defense described Effect element Epidemic evaluate event Factor feature function functions functions human milk factors high mortality rate human milk human milk research immunoregulatory effect immunoregulatory effects in viral Infant Infants Infection mechanism milk Organ failure pathogenic property protection Research Side effects Spread systemic inflammation therapy Topic Viral viral infections viral invasion [DOI] 10.3389/fpubh.2020.589736 PMC 바로가기 [Article Type] Public Health
Use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers associated with lower risk of COVID-19 in household contactsResearch Article Published on 2021-03-022022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] 95% CI ACEi adjusted Affect age analyses Analysis angiotensin receptor blocker ARB association cardiovascular disease clinical condition Cohort cohort study Comorbidity conducted COVID-19 COVID-19 diagnosis determine diabete diagnosed with COVID-19 Effect EMR enzyme exclusion functions health system household household contact household transmission hypertension individual inhibitor Logistic regression lower risk medication objective Observational data Older Patient positive predicted Probability recommendation Result risk risk of COVID-19 SARS-CoV-2 Sociodemographic characteristics study period subgroups Support tested were used while [DOI] 10.1371/journal.pone.0247548 PMC 바로가기 [Article Type] Research Article
DPP-4 inhibition and COVID-19: From initial concerns to recent expectationsDPP-4 억제와 코로나19: 초기 우려에서 최근 기대까지Review Published on 2021-03-012022-08-31 Journal: Diabetes & metabolism [Category] SARS, 바이오마커, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission Admissions Anti-inflammatory effects Antigen appear benefit best binding domain CD26 Clinical outcome clinical outcomes Clinical practice coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient cytokine Cytokine storm Cytokine storms diabete diabetes dipeptidyl peptidase domain enzyme expressed form functional functions Gliptin heterogeneous high affinity Host Hypothesis hypothetical Immune cell immune cells Incretin infections Inflammation inherent inhibitor initial intensive care unit intensive care units limitation management Mortality observational studies outcome Patient patients with COVID-19 positive progression Randomized controlled trial Randomized controlled trials receptor recommendation reductions in regulate respiratory responsible retrospective risk Safe safety profile SARS-CoV-2 severe acute respiratory syndrome Coronavirus significant reductions susceptibility susceptibility to infections T-cell the disease type 2 diabete Type 2 diabetes mellitus virus while [DOI] 10.1016/j.diabet.2020.11.005 PMC 바로가기 [Article Type] Review
C1q Complement/Tumor Necrosis Factor-Associated Proteins in Cardiovascular Disease and COVID-19Review Published on 2021-03-012022-10-29 Journal: Proteomes [Category] COVID-19, [키워드] association C1q cardiovascular cardiovascular complication cardiovascular disease cardiovascular system Chronic disorder COVID-19 CTRPs CVD diabetes dysfunction Endothelial cell Evidence functions homeostasis immune IMPROVE indicate Inflammation Injury knowledge metabolism Mortality mortality rate much higher Necrosis Novel coronavirus obesity overall mortality paralog Patient Patient care patients potential mechanisms Prognosis progression Protein reduce reduced SARS-CoV-2 secreted significantly Surveillance therapeutic strategy treatment strategy understanding [DOI] 10.3390/proteomes9010012 PMC 바로가기 [Article Type] Review