Heart up! RCT protocol to increase physical activity in cardiac patients who report hopelessness: Amended for the COVID-19 pandemic마음을 위로! 절망감을 호소하는 심장병 환자의 신체 활동을 증가시키는 RCT 프로토콜: COVID-19 범유행을 위해 수정됨Article Published on 2021-04-012022-09-11 Journal: Research in nursing & health [Category] 임상, [키워드] adverse event adverse events aims cardiac Cardiac rehabilitation Care contribute COVID-19 COVID-19 pandemic death determine Effect Effectiveness enrolled finding Health heart heart disease hopelessness IHD Intervention investigated ischemic heart disease maintain moderate Nurse outcomes participant Patient per day physical physical activity promote protocol Randomized Randomized controlled trial Rate RCT rehabilitation Research Research protocol research protocol. researcher Self-management Significant other Social support SOS Support three groups while [DOI] 10.1002/nur.22106 PMC 바로가기 [Article Type] Article
Clearing the Fog: Is Hydroxychloroquine Effective in Reducing Coronavirus Disease-2019 Progression? A Randomized Controlled TrialInternal Medicine Published on 2021-03-302022-10-31 Journal: Cureus [Category] COVID-19, [키워드] A p-value addition age analyzed assigned Clearing conducted control group Controlled Controlled trial coronavirus disease coronavirus disease-2019 COVID-19 Disease progression Efficacy Emirate enrolled HCQ help Hospitalized IBM Intervention intervention group Mild mild COVID-19 patient mild infection negativity Patient patients PCR PCR negativity polymerase chain progressed RCT reducing Result Science secondary outcome Standard dose Standard of care Statistical Package sustained Treatment viral clearance [DOI] 10.7759/cureus.14186 PMC 바로가기 [Article Type] Internal Medicine
Masks, mechanisms and Covid-19: the limitations of randomized trials in pandemic policymaking마스크, 메커니즘 및 Covid-19: 전염병 정책 결정에서 무작위 시험의 한계Article Published on 2021-03-252022-09-11 Journal: History and philosophy of the life sciences [Category] SARS, 임상, [키워드] approach contrary COVID-19 Evidence expected Factor failure limitation Mask Masks mechanism offset pandemic Pandemics positive randomized control trial Randomized control trials Randomized control trials. randomized trial RCT RCTs reduce reflect required Transmission trials [DOI] 10.1007/s40656-021-00403-9 PMC 바로가기 [Article Type] Article
Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19: A Systematic Review and Meta-analysisCOVID-19 환자의 회복기 혈장 치료와 임상 결과의 연관성: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-03-232022-09-11 Journal: JAMA [Category] 임상, [키워드] 95% CI all-cause mortality Analysis assessment assessment tool benefit Bia certainty Characteristics clinical Clinical deterioration Clinical improvement Clinical outcome clinical outcomes conducted convalescent plasma convalescent plasma treatment COVID-19 data extraction decrease development Evidence hazard ratio Hospital stay Inclusion inverse Limited mechanical ventilation Meta-analysis moderate Mortality no significant differences Other outcomes outcome outcomes Patient peer-reviewed Placebo plasma platform press primary analysis randomized clinical trial randomized clinical trials RCT RCTs Release releases review risk risk difference risk ratio searched selected Serious Adverse Event Serious Adverse Events significant differences significantly Standard of care synthesis Treatment treatment effects treatment for COVID-19 Trial [DOI] 10.1001/jama.2021.2747 PMC 바로가기 [Article Type] Meta-Analysis
Interleukin-6 blocking agents for treating COVID-19: a living systematic reviewCOVID-19 치료를 위한 인터루킨-6 차단제: 살아있는 체계적인 검토Meta-Analysis Published on 2021-03-182022-09-11 Journal: The Cochrane database of systematic reviews [Category] 임상, 진단, [키워드] 95% CI adverse event adverse events age all-cause mortality anti-IL6 approach articles available data average baseline benefit Bia blocking agent blocking agents Brazil can not Care certainty certainty of evidence China clinical Clinical improvement Cochrane COVID-19 Study Register collected data conducted coronavirus disease Coronavirus disease 2019 COVID-19 Critical Critical disease Data collection death defined disease disease severity Efficacy and safety eight evaluate evaluated Evidence excluded FIVE Follow-up France Health Organization heterogeneity hospital discharge identify IL-6 IL-6 blocking Immune system dysfunction immunosuppressive incidence Inclusion individual individual patient data meta-analyses Inflammation interleukin interleukin 6 interleukin 6 (IL-6 Intubated intubated patient intubated patients Italy male mechanical ventilation Meta-analysis methodology Mild moderate Mortality multicentre nine no increase not intubated organ support Other outcomes outcome outcomes oxygen participant Participants Patient patient data patients with COVID-19 peer-reviewed people with COVID-19 Placebo platform Platform trial progression proportion protocol randomised randomised controlled trial Randomised controlled trials ranged RCT RCTs reduce Registered registry reported risk of bia Safety sarilumab score searched Selection Serious Adverse Event Serious Adverse Events Seven severe coronavirus disease severity siltuximab standard care Standard of care subgroups of patient systematic review Tocilizumab Tolerance Treatment Trial trial participant trial participants trials unlikely USA WHO World Health Organization [DOI] 10.1002/14651858.CD013881 PMC 바로가기 [Article Type] Meta-Analysis
Community Health Workers as a Strategy to Tackle Psychosocial Suffering Due to Physical Distancing: A Randomized Controlled TrialRandomized Controlled Trial Published on 2021-03-172022-10-04 Journal: International Journal of Environmental Research an [Category] SARS, 임상, [키워드] Anxiety baseline Community community health workers Control Controlled COVID COVID-19 COVID-19 pandemic determine Effectiveness emotional Evidence Health Health crisis health worker healthcare implementation Intervention intervention group Measures mental health Patient physical distancing measure Population primary care Primary Healthcare professional provided Psychosocial psychosocial support Randomized controlled trial RCT Research significant effect social isolation Strategy suffering Support tested vulnerable patient Vulnerable populations was determined were measured worker [DOI] 10.3390/ijerph18063097 PMC 바로가기 [Article Type] Randomized Controlled Trial
Arguments about face masks and Covid-19 reflect broader methodologic debates within medical science안면 마스크와 Covid-19에 대한 논쟁은 의학 내에서 광범위한 방법론적 논쟁을 반영합니다.Review Published on 2021-03-162022-09-10 Journal: European Journal of Epidemiology [Category] MERS, 임상, [키워드] approach argument Causal inference Causality debate disease epidemiological Epidemiology Evidence Evidence synthesis exclusion Face mask Face masks focus gold gold standard increasingly magnitude Methods observational studies observational study priority Randomized controlled trial RCT RCTs Regulatory Support [DOI] 10.1007/s10654-021-00735-7 PMC 바로가기 [Article Type] Review
New Methodologies for Conducting Maternal, Infant, and Child Nutrition Research in the Era of COVID-19Article Published on 2021-03-152022-10-30 Journal: Nutrients [Category] COVID-19, [키워드] activities acute respiratory syndrome change changes Child childhood clinical trial Conducting coronavirus coronavirus disease COVID-19 COVID-19 pandemic COVID-19 transmission face-to-face contact healthcare implication increased risk infancy Infant Maternal methodology Modification New nutrition outbreak outcome pandemic Participants Population Potential participants Pregnancy pregnant women RCT required Research research methods worldwide pandemic [DOI] 10.3390/nu13030941 PMC 바로가기 [Article Type] Article
Chinese Herbal Medicine Used With or Without Conventional Western Therapy for COVID-19: An Evidence Review of Clinical StudiesPharmacology Published on 2021-02-262022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] 95% CI 95% confidence interval addition adverse events Analysis analyzed Characteristics Chest CT Chinese Chinese herbal medicine CHM clinical clinical study Comparator group control group control groups Controlled trial Conventional Coronavirus disease 2019 cough COVID-19 current duration of fever evaluated Evidence fatigue FIVE Herbal injection intervention group manifestation mean difference Medicine Methodological quality Negative conversion rate no statistical difference non-randomized novel coronavirus pneumonia nucleic acid test Randomized controlled trial RCT RCTs receiving reducing Retrospective study review risk risk of bia SARS-CoV-2 statistical difference tested therapeutic effect therapy therapy for COVID-19 Traditional Chinese medicine Treatment [DOI] 10.3389/fphar.2020.583450 PMC 바로가기 [Article Type] Pharmacology
Efficacy and safety of systematic corticosteroids among severe COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials중증 코로나19 환자를 대상으로 한 전신 코르티코스테로이드의 효능 및 안전성: 무작위 대조 시험에 대한 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-02-212022-09-10 Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, MERS, 임상, [키워드] 95% confidence interval all-cause mortality Analysis applied approach assessment benefit calculate certainty CIs Controlled controlled trials coronavirus disease Coronavirus disease 2019 Corticosteroid Corticosteroids COVID-19 COVID-19 therapy death development Disease progression Enrollment evaluate evaluated Evidence excluded extracorporeal membrane oxygenation Follow-up ICU identify Immunotherapy incidence Infectious diseases intubation Meta-analysis not increased Occurrence outcome Patient Primary outcome progression random-effects model Randomized controlled trial Randomized controlled trials RCT RCTs recovery RECOVERY trial required Result risk risk ratio searched secondary Secondary outcomes sequential analysis Serious Adverse Event Serious Adverse Events severe coronavirus disease severe COVID-19 severe COVID-19 patients subjects suggested survival systematic corticosteroid systematic review transfer Trial trial sequential analysis Ventilated Ventilation [DOI] 10.1038/s41392-021-00521-7 PMC 바로가기 [Article Type] Meta-Analysis