Vitamin D status of Arab Gulf residents screened for SARS-CoV-2 and its association with COVID-19 infection: a multi-centre case–control studyResearch Published on 2021-04-262022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, MERS, SARS, [키워드] 95% CI age Anthropometrics association being blood sample BMI Case–control cholesterol collected Comorbidities Concentration concentrations conducted confidence COVID-19 COVID-19 infection determine Diabetes Mellitus female Glucose Gulf HDL independent individuals Infection Inflammatory marker interval lipids male medical history Mild symptom negative controls obesity objective patients with COVID-19 positive presenting protective effect Randomized controlled trial Result risk factor risk of COVID-19 SARS-CoV-2 saudi screened serum Sex significantly significantly lower supplementary material T2D tested the SARS-CoV-2 type 2 diabete Vitamin D Vitamin D supplementation were measured with COVID-19 [DOI] 10.1186/s12967-021-02838-x PMC 바로가기 [Article Type] Research
An Early Warning Tool for Predicting Mortality Risk of COVID-19 Patients Using Machine LearningArticle Published on 2021-04-212022-10-31 Journal: Cognitive Computation [Category] COVID-19, [키워드] age AUC Biomarker Blood calculated China Clinical characteristics conducted COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 positive patient cutoff value dataset death demographic disease Early warning tool extreme global healthcare group help high mortality High-sensitivity C-reactive protein hospital identify IMPROVE investigated less lymphocyte machine learning management Mortality mortality risk neutrophil outcome Patient patients predict Predicting mortality risk predictor Probability prognostic model reduce mortality resource Retrospective study risk of COVID-19 severity Stratification the disease Tongji Hospital validation cohort [DOI] 10.1007/s12559-020-09812-7 PMC 바로가기 [Article Type] Article
Impact of the COVID-19 Pandemic and Obstetrician and Gynecologist Workforce Distribution on Vaccine Deployment and Predicting Women’s Healthcare ShortagesObstetrics/Gynecology Published on 2021-04-182022-10-31 Journal: Cureus [Category] COVID-19, [키워드] age asymptomatic patient benefit college Community Coronavirus pandemic COVID-19 COVID-19 case COVID-19 patient COVID-19 vaccine Critical distribution early stage evaluate geographical distribution gynecologist healthcare highest Impact Johns Hopkins University mitigate New North obstetrician obstetricians and gynecologists Older physician predicted proportion provide reported Result risk of COVID-19 South The United States Vaccine Vaccines with COVID-19 women’s health [DOI] 10.7759/cureus.14545 PMC 바로가기 [Article Type] Obstetrics/Gynecology
Is Re-introducing Major Open and Minimally Invasive Surgery during COVID-19 Safe for Patients and Healthcare Workers? An International, Multi-centre Cohort Study in the Field of Oesophago-gastric SurgeryObservational Study Published on 2021-04-172022-10-04 Journal: Annals of Surgical Oncology [Category] MERS, SARS, 임상, [키워드] Cancer Care change Complete complex concern consecutive patient COVID-19 COVID-19 pandemic determine disease eligible European field for inclusion Health healthcare worker incidence of COVID-19 Infection International invasive involved Major MIS mitigate Mortality nine operative Patient Patient care Precaution primary endpoint raised recruited Region Result risk risk of COVID-19 Safe supplementary material surgery treated [DOI] 10.1245/s10434-021-09885-0 PMC 바로가기 [Article Type] Observational Study
Relation between Vitamin D and COVID-19 in Aged People: A Systematic ReviewReview Published on 2021-04-172022-10-31 Journal: Nutrients [Category] COVID-19, MERS, SARS, [키워드] activating Adaptive immune response addition administration adverse outcome adverse outcomes aged people appear articles association basic benefit Characteristics COVID-19 COVID-19 patient death death rate deficiency Effect Evidence Final greater identify immune system Innate immunity Invasive mechanical ventilation observational study overactive Oxygen therapy Patient patients primary clinical outcome reducing Registered relation review risk risk of COVID-19 Seven severity Side effects Study design study population subject Support systematic review the disease Viral diseases Vitamin D Vitamin D supplementation was performed were excluded [DOI] 10.3390/nu13041339 PMC 바로가기 [Article Type] Review
Highlighting the compound risk of COVID-19 and environmental pollutants using geospatial technologyArticle Published on 2021-04-162022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] affected atmospheric authors changes community transmission Concentration condition coronavirus disease country COVID-19 COVID-19 pandemic declined exacerbate Health infections Local lockdown National pandemic partial lockdown Projection and prediction reduced rehabilitation respiratory diseases restrict risk risk of COVID-19 severity of COVID-19 Side effect significantly Variation [DOI] 10.1038/s41598-021-87877-6 PMC 바로가기 [Article Type] Article
Term Human Placental Trophoblasts Express SARS-CoV-2 Entry Factors ACE2, TMPRSS2, and Furin용어 인간 태반 영양막은 SARS-CoV-2 진입 인자 ACE2, TMPRSS2 및 푸린을 발현합니다Research Article Published on 2021-04-142022-09-10 Journal: mSphere [Category] MERS, SARS, 유전자 메커니즘, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect affected angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Blood bloodstream caused cell type cell types cells Combination coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Defense demonstrated entry of SARS-CoV-2 enzyme Express expresse expressed expression expression of SARS-CoV-2 Factor Factors furin highest Human immunofluorescence In situ hybridization Infection Intervention Lungs maternal blood organ pandemic Particles Placenta placental Placental infection pregnant women protease pseudovirus quantitative PCR respiratory risk risk of COVID-19 RNA-Seq RT-qPCR SARS-CoV-2 SARS-CoV-2 entry factor SARS-CoV-2 entry factors SARS-COV-2 infection SARS-CoV-2 pseudovirus Serine serine 2 severe acute respiratory syndrome Coronavirus spread to term tested TMPRSS2 Transcriptome transcriptome sequencing transmembrane transmembrane protease serine 2 Transmission trophoblast Viremia virus while women [DOI] 10.1128/mSphere.00250-21 PMC 바로가기 [Article Type] Research Article
Low risk of SARS-CoV-2 in blood transfusion수혈 시 SARS-CoV-2의 낮은 위험Research Article Published on 2021-04-132022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 age all subject all subjects Asymptomatic Blood Blood donors Blood Transfusion caused China classical clinically collected conducted Contact convalescent coronavirus disease Coronavirus-2 cough COVID-19 criteria cross-sectional Cycling determine diagnostics discharge evaluate Evidence evidence of genomic region hematogenous individual individuals infected individual infected individuals KNUST LBP male Medicine minimum Novel coronavirus novel coronavirus disease nucleic acid nucleic acid extraction ORF1ab pandemic Patient PCR plasma populations positive potential risk predominant Prevalence Real-time PCR recovered patients recruited reported respiratory Result Retrospective study risk risk of COVID-19 Saliva SARS-CoV-2 SARS-CoV-2 testing SARS-CoV-2 viral RNA SARS-CoV-2 virus Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus sputum Sputum sample subject subjects Symptom symptomatic symptoms of COVID-19 tested threshold Transmission transmission of SARS-CoV-2 transmitted transported tropical medicine Viral viral nucleic acid Viremia virus was performed [DOI] 10.1371/journal.pone.0249069 PMC 바로가기 [Article Type] Research Article
Personal protective equipment for reducing the risk of COVID-19 infection among health care workers involved in emergency trauma surgery during the pandemic: An umbrella reviewReview Article Published on 2021-04-122022-10-30 Journal: The journal of trauma and acute care surgery [Category] COVID-19, MERS, SARS, [키워드] adhere approach Assessing assessment automated broad evidence synthesis Canada Care conducted Contagion Controlled country COVID-19 criteria decontamination development Effect effective Efficacy ENhance equipment Evidence evidence-based practice eye feasible global health Health health care facility Health care worker health care workers hydrogen peroxide Infection involved Mask Masks measure moderate N95 masks N95 respirator not affect observational study overcome patients Personal protective equipment platform PPE Prospective Protective Quality recommendations reduce reduced risk reducing reduction in Registered reported resources Respirator reuse review risk risk of COVID-19 surgical trauma Trauma surgery ultraviolet Umbrella review [DOI] 10.1097/TA.0000000000003073 PMC 바로가기 [Article Type] Review Article
Are psychiatric disorders risk factors for COVID-19 susceptibility and severity? a two-sample, bidirectional, univariable, and multivariable Mendelian Randomization studyArticle Published on 2021-04-082022-10-04 Journal: Translational Psychiatry [Category] MERS, 유전자 메커니즘, [키워드] 95% CI Analysis applied association bidirectional Bipolar disorder BMI Bonferroni-corrected Clinical genetics contributing to controls correlation covariate COVID-19 COVID-19 phenotype COVID-19 phenotypes COVID-19 susceptibility disorder disorders Generalized Genetic genetic data genetic instrument Genome-wide association study GWAS GWASs implicated increased the risk limitation multivariable multivariable analysis Multivariable MR Neuropsychiatric observational studies observational study overcome Phenotypes pleiotropic effect positive psychiatric disorder released remained reported risk factor risk of COVID-19 Schizophrenia sensitivity analysis severity statistical model suggested univariable univariable analysis with COVID-19 [DOI] 10.1038/s41398-021-01325-7 PMC 바로가기 [Article Type] Article