Vaccines – Page 311 – Communicable Diseases Research

A new perspective for mitigation of SARS-CoV-2 infection: priming the innate immune system for viral attack

1001

Published on 2020-07-292022-10-29
Journal: Open Biology [Category] COVID-19,

[키워드] Activation Adults Anti-viral applied Asymptomatic carried cascade Clinical outcome clinical trial Complication Course COVID-19 death disease elevated elicit epidemiological evade Evidence example expected faster Hospitalization Hypothesis immune dysregulation immune factor immune response include individual individual level individuals infect Infection innate immune response innate immune system less Mild symptom mitigate occur Perspective pre-activation priming Probability reducing risk robust SARS-CoV-2 SARS-COV-2 infection severity Spread supported the epidemic Therapeutic approach trained immunity trajectory Vaccine Vaccines virus
[DOI] 10.1098/rsob.200138 PMC 바로가기 [Article Type] 1001

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

Brief Communication

Published on 2020-07-272022-10-30
Journal: NPJ Vaccines [Category] COVID-19,

[키워드] adenoviral vector antibody antigen-specific antibody booster ChAdOx1 nCoV-19 clinical COVID-19 vaccine dose expressing full-length SARS-CoV-2 initiated mice neutralising non-human primate Protein responses SARS-CoV-2 significant increase single dose T cells responses titres vaccination Vaccines Virology
[DOI] 10.1038/s41541-020-00221-3 PMC 바로가기 [Article Type] Brief Communication

Structure-based design of prefusion-stabilized SARS-CoV-2 spikes

Report

Published on 2020-07-232022-10-28
Journal: Science (New York, N.y.) [Category] COVID-19, Fulltext, SARS,

Emerging manufacturers engagements in the COVID −19 vaccine research, development and supply

Article

Published on 2020-07-222022-10-29
Journal: Vaccine [Category] COVID-19,

Sequence analysis and pathogenicity of Avian Orthoavulavirus 1 strains isolated from poultry flocks during 2015–2019

Research Article

Published on 2020-07-222022-10-28
Journal: BMC veterinary research [Category] Coronavirus,

[키워드] Amino acid residue substitution Analysis Avian Orthoavulavirus 1 cause Co-infection decrease Delta disease examined F protein fusion protein gene sequence genetic analysis Genotype glycosylation high mortality highly pathogenic IBV indicated Infectious Bronchitis Virus Influenza Intensive Intracerebral isolate isolates Isolation molecular motif neutralizing epitopes newcastle disease virus pathogenic pathogenicity positive Prevalence primer qRT-PCR ranged RBCs reduce residue respiratory viral disease Result selected sequenced Sequencing Seven Spread strain submitted suffered tested vaccination Vaccines
[DOI] 10.1186/s12917-020-02470-9 PMC 바로가기 [Article Type] Research Article

COVID-19: Mechanisms of Vaccination and Immunity

Review

Published on 2020-07-222022-10-28
Journal: Vaccines [Category] COVID-19,

Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2

Research Article

Published on 2020-07-212022-10-29
Journal: mBio [Category] COVID-19, SARS,

[키워드] acute respiratory syndrome addition Antibody Response assist characterization circulating coronavirus country COVID-19 Deletion deletion variant deletions described eliminating epidemiological Evidence Frame genetic change Genome Host hosts Human humans Hypothesis immune evasion immune response in vitro lack natural selection no difference ORF7b ORF8 Patient Phylogeny predominant reduced replicative fitness retained robust SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain screened significantly higher Singapore Spain sustained Taiwan the SARS epidemic the SARS-CoV-2 Transcription transcription regulatory sequence transmission of SARS-CoV-2 TRS Vaccination strategies Vaccines Viral load virus virus attenuation wild type
[DOI] 10.1128/mBio.01610-20 PMC 바로가기 [Article Type] Research Article

A rational roadmap for SARS‐CoV‐2/COVID‐19 pharmacotherapeutic research and development: IUPHAR Review 29

Review Article

Published on 2020-07-192022-10-28
Journal: British Journal of Pharmacology [Category] COVID-19, SARS,

[키워드] approach article clinical trials COVID‐19 drug Drug discovery drug resistance evade global pandemic Host identify mitigate Pharmacology Research review second target therapeutic strategy Threats translation Treatment Vaccines
[DOI] 10.1111/bph.15094 PMC 바로가기 [Article Type] Review Article

Advances in the possible treatment of COVID-19: A review.

Article

Published on 2020-07-172023-07-01
Journal: European journal of pharmacology [Category] SARS,

[키워드] antivirals COVID-19 Epidemiology Therapeutics treatments Vaccines
[DOI] 10.1016/j.ejphar.2020.173372 PMC 바로가기 [Article Type] Article

An updated insight into the molecular pathogenesis, secondary complications and potential therapeutics of COVID-19 pandemic

Article

Published on 2020-07-172023-07-01
Journal: Life sciences [Category] SARS,