Current Status of Multiple Drug Molecules, and Vaccines: An Update in SARS-CoV-2 TherapeuticsReview Published on 2020-07-152023-06-15 Journal: Molecular neurobiology [Category] MERS, SARS, [키워드] HCQ Protease inhibitor Remdesivir SARS-CoV-2 Vaccines [DOI] 10.1007/s12035-020-02022-0 PMC 바로가기 [Article Type] Review
Rapid Quantification of SARS-CoV-2-Neutralizing Antibodies Using Propagation-Defective Vesicular Stomatitis Virus PseudotypesArticle Published on 2020-07-152022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome analyzed antibodies antiviral therapy approved biosafety Biosafety Level 3 can be used caused classical coefficient convalescent COVID-19 patient convalescent COVID-19 patients coronavirus correlated detect determine displaying genus Betacoronavirus homologous Immune status morbidities MOST neutralization titer neutralized Neutralizing antibodies neutralizing antibody Neutralizing antibody titer pandemic virus passive immunization patient cohort Pearson correlation performed pseudotype virus pseudovirus quantification Rapid robust SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 neutralization SARS-CoV-2-neutralizing antibodies SARS-CoV-2-neutralizing antibody sera serum Spike protein the SARS-CoV-2 therapeutic vaccinated individuals Vaccine Vaccines vesicular vesicular stomatitis virus VSV [DOI] 10.3390/vaccines8030386 PMC 바로가기 [Article Type] Article
COVID-19 vaccine development and a potential nanomaterial path forward Reviews Published on 2020-07-152022-10-05 Journal: Nature nanotechnology [Category] SARS, 임상, [키워드] adjuvants Antigen approach benefit clinical trial coronavirus COVID-19 pandemic COVID-19 vaccine development distribution genome sequence highlight inactivated Incubation period lack Lipid nanoparticles mitigate mRNA vaccine Nanotechnology nCoV Pandemics Prevalence Prophylaxis Protein SARS-CoV-2 structures Subunit vaccine Treatment Vaccine vaccine candidate Vaccine design vaccine platform Vaccines viral strains [DOI] 10.1038/s41565-020-0737-y [Article Type] Reviews
Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development530 Published on 2020-07-142022-10-29 Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, SARS, [키워드] acute respiratory syndrome addition animal model antiviral drugs Characteristics China consequence consolidation convalescent serum coronavirus coronavirus disease countermeasure COVID-19 patient disease feature Ground glass opacity hamster hamsters Health human lung immunotherapies Infection inhibited intranasal isolate lesion lung lung lesion Lungs mounted naïve Neutralizing antibody response Novel coronavirus pathogenesis of SARS-CoV-2 Pneumonia Postinfection Region replicate replicated Replication replicative reported SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 isolate SARS-CoV-2 pathogenesis serum severe lung injury Significance Spread subsequent suppressed Syrian hamsters transfer Vaccine Vaccines virus virus replication Wuhan, China [DOI] 10.1073/pnas.2009799117 PMC 바로가기 [Article Type] 530
Impact of Vaccines; Health, Economic and Social PerspectivesReview Published on 2020-07-142024-09-02 Journal: Frontiers in Microbiology [Category] 대상포진, [키워드] children health economics immunization Infection Infectious diseases Vaccines [DOI] 10.3389/fmicb.2020.01526 PMC 바로가기 [Article Type] Review
Human monkeypox – After 40 years, an unintended consequence of smallpox eradicationArticle Published on 2020-07-142023-06-09 Journal: Vaccine [Category] Fulltext, 원숭이두창, [키워드] Epidemiology eradication Monkeypox Orthopox risk smallpox Vaccines [DOI] 10.1016/j.vaccine.2020.04.062 PMC 바로가기
Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19Review Published on 2020-07-132022-11-01 Journal: Critical Care [Category] COVID-19, [키워드] Abstract ACE2 ACE2 receptor ACE2-expressing cell acute respiratory syndrome addition angiotensin-converting enzyme 2 antibodies attenuate bind caused contribute coronavirus coronavirus disease counteract COVID-19 downregulation drugs Effect expressed global pandemic help host cell immune factor infect Infection Inflammatory Injury Local lung lung cell Multi-organ injury organ organ injury organs other organ outbreak Pathogenesis pathophysiological physiological Pneumonia RAS receptor renin-angiotensin system Restoring role SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike glycoprotein spread to Vaccines virus WHO with COVID-19 World Health Organization Wuhan, China [DOI] 10.1186/s13054-020-03120-0 PMC 바로가기 [Article Type] Review
Recent Advancements in the Diagnosis, Prevention, and Prospective Drug Therapy of COVID-19Review Published on 2020-07-102022-10-04 Journal: Frontiers in Public Health [Category] MERS, 신약개발, [키워드] 2019-nCoV acute respiratory syndrome advancement approved approved drugs carried cause China clinical condition clinical trial clinical trials common cold confirmed case coronavirus CoV COVID-19 CoVs death Diagnosis diagnostic tests drug Drug repurposing Efficacy and safety Evidence global pandemic illness imperative in vitro International lack outbreak Outbreaks prevention Prospective public health emergency recent reduction in Respiratory illness SARS-CoV-2 severity Treatment treatment approach Vaccines virus WHO World Health Organization [DOI] 10.3389/fpubh.2020.00384 PMC 바로가기 [Article Type] Review
A replication-competent late liver stage-attenuated human malaria parasiteArticle Published on 2020-07-092024-08-28 Journal: JCI Insight [Category] 말라리아, [키워드] Infectious disease malaria Parasitology Vaccines
Viral Evasion of the Complement System and Its Importance for Vaccines and TherapeuticsImmunology Published on 2020-07-092022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] adaptive Adaptive immune response Antiviral effect antivirals chemotaxis complement complement system COVID-19 pandemic dengue virus disease disease symptoms dysregulation Effective vaccines Effects ENhance evade exacerbate Extracellular Factor functions Genetic host response Immunity immunology Importance induce Inflammatory responses Innate immunity Interaction mechanism microorganisms neutralization Nipah virus occur outcome Pathogenesis Pathogens pathway PROTECT Regulation Research respond Stage System Therapeutics this system Vaccines viral infection viral infections viral infectivity Virology virus viruses West Nile Virus [DOI] 10.3389/fimmu.2020.01450 PMC 바로가기 [Article Type] Immunology