High Resolution CT Imaging Dynamic Follow-Up Study of Novel Coronavirus PneumoniaMedicine Published on 2020-05-042022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] analyzed change Characteristics Clinical characteristics Clinical features common COVID-19 COVID-19 pneumonia patient Critical CT imaging disease severity dynamic epidemiological Evolution females Follow-up high resolution CT HRCT imaging in some involved Laboratory lesion lung Lung injury male manifestation median age novel coronavirus pneumonia nucleic acid test Patient Pneumonia positive Resolution statistically significant tomography Treatment X-ray computed [DOI] 10.3389/fmed.2020.00168 PMC 바로가기 [Article Type] Medicine
Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencingArticle Published on 2020-05-042022-10-31 Journal: Cell Discovery [Category] COVID-19, [키워드] affected Analysis antibody B cells BCR caused CD14 CD4 CD8 Cell change classical Course COVID-19 COVID-19 patient COVID-19 patients early recovery Evidence expressed frequencies Gene Expression greater hospital discharge identification IGHV3-15 IGHV3-23 IGHV3-30 IGHV3-7 IGKV3-11 IL-18 IL-1β IL-2 IL-4 IL1β Immune cell immune signature immunology indicated Inflammatory inflammatory gene inflammatory storm isotype M-CSF Mechanisms of disease monoclonal monocyte mononuclear cell naïve B cell Patient Peripheral blood Plasma cell predicted provide reported SARS-CoV-2 Sequencing Signaling significantly single-cell Single-cell RNA sequencing specificity subset T cell target gene TNFSF13 transcriptional change Treatment Vaccine Vaccine development virus [DOI] 10.1038/s41421-020-0168-9 PMC 바로가기 [Article Type] Article
Efficacy and safety of lower dose tenofovir disoproxil fumarate and efavirenz versus standard dose in HIV-infected, antiretroviral-naive adults: a multicentre, randomized, noninferiority trialHIV 감염, 항레트로바이러스 경험이 없는 성인에서 표준 용량 대비 저용량 테노포비르 디소프록실 푸마르산염 및 에파비렌즈의 효능 및 안전성: 다기관, 무작위, 비열등성 시험Article Published on 2020-05-042022-09-06 Journal: Emerging Microbes & Infections [Category] Communicable Disease, [키워드] 95% CI adverse event adverse events antiretroviral ARV assigned change comparable dose drug efavirenz Efficacy evaluate filtration rate fumarate glomerular filtration rate HIV HIV-1 HIV-1 infection infected patients initial intention-to-treat analysis lamivudine low dose lower dose lower toxicity multicentre non-inferiority non-inferiority margin non-inferiority trial occurred Open-label participant primary endpoint proportion Randomized Randomly receive receiving reduced regimen safety profile Standard dose Support tenofovir tenofovir disoproxil tenofovir disoproxil fumarate therapy Toxicity Treatment treatment difference Trial two groups [DOI] 10.1080/22221751.2020.1752609 PMC 바로가기 [Article Type] Article
Psychological and Behavioral Response to the Coronavirus (COVID-19) PandemicPsychology Published on 2020-05-022022-10-31 Journal: Cureus [Category] COVID-19, [키워드] addition Administered age alleviate analyzed Anxiety Avoidance behavior behavioral impact change changes changes in chi-square test conducted Corona virus correlation COVID-19 distress elevated Gender global pandemic Health healthcare facility help Hopefully IBM identify individual infection control Karachi majority measure media outbreak Pakistan pandemic participant physical contact Psychological psychological Impact Psychological well-being questionnaire reduced Research response Result risk factor Science Spread SPSS statistical Statistical Package subsequent the disease their family member virus washing hand Wuhan, China [DOI] 10.7759/cureus.7923 PMC 바로가기 [Article Type] Psychology
Imaging manifestations and diagnostic value of chest CT of coronavirus disease 2019 (COVID-19) in the Xiaogan areaResearch article Published on 2020-05-012022-10-05 Journal: Clinical radiology [Category] SARS, 진단, [키워드] Accuracy analysed Blood oxygen saturation change characteristics of patient Chest Chest computed tomography Chest CT chest infection China Complete consolidation coronavirus disease correlation COVID-19 COVID-19 patient demonstrated diagnostic diagnostic value distribution early diagnosis epidemiological fused ground-glass opacity imaging involved lesion lung lymphocyte manifestation morphology negative correlation Nucleic acid detection patchy Patient patients progression radiological sensitivity severity treated with COVID-19 zone [DOI] 10.1016/j.crad.2020.03.004 [Article Type] Research article
ACE2 correlated with immune infiltration serves as a prognostic biomarker in endometrial carcinoma and renal papillary cell carcinoma: implication for COVID-19Research Paper Published on 2020-04-302022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, SARS, [키워드] ACE2 ACE2 expression addition Analysis analyzed B cell carcinoma Cell change correlated correlation COVID-19 COVID-19 patient database dendritic cell elevated Endometrial Carcinoma enzyme expression expression level Immune cell immune infiltration in vitro in vivo investigated Kaplan-Meier Macrophage macrophages marker Methylation neutrophil Neutrophils Papillary performed positively correlated Prognosis prognostic biomarker promoter reduced renal SARS-CoV infection SARS-CoV-2 SARS-COV-2 infection significantly subgroup survival susceptible tissue was tested [DOI] 10.18632/aging.103100 PMC 바로가기 [Article Type] Research Paper
Gilles de la Tourette Syndrome: advice in the times of COVID-19Opinion Article Published on 2020-04-282022-10-31 Journal: F1000Research [Category] COVID-19, MERS, SARS, [키워드] addition ADHD Anxiety change China clinical symptom co-morbidities confinement COVID-19 COVID-19 illness COVID-19 pandemic death disorder dry cough exacerbated Germane Gilles de la Tourette syndrome GTS Health include information national health system novel coronavirus disease OCD outbreak pandemic Patient press Prevalence Psychiatric reported Respiratory disease Spread Symptom tics [DOI] 10.12688/f1000research.23275.2 PMC 바로가기 [Article Type] Opinion Article
Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent PlasmaResearch Published on 2020-04-282022-11-01 Journal: JAMA [Category] COVID-19, SARS, [키워드] acute respiratory distress acute respiratory syndrome Administered administration Admission age Antiviral antiviral agent Antiviral treatment approach ARDS assessment binding blood biochemical body temperature case sery change China Chinese patient clinical Clinical outcome clinical status clinical trials conducted convalescent plasma coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical Critically ill patient determine Dilution discharged ECMO Effectiveness ELISA end point enzyme-linked immunosorbent exposure extracorporeal membrane oxygenation failure Final finding Follow-up greater hospital Human plasma IgG Ill Importance Infection Infectious disease laboratory-confirmed limited sample size measure mechanical ventilation Methylprednisolone Mortality neutralization titer neutralizing antibody Neutralizing antibody titer normalized objective observation outcome pandemic participant Patient patients plasma Plasma transfusion Point preliminary finding progression raise randomized clinical trials receiving recovered patients Relevance resolved Result SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2–specific antibody serum antibody setting severe pneumonia Shenzhen SOFA SOFA score Study design Support syndrome therapeutic agent treated Treatment ventilatory Viral load were given with COVID-19 women [DOI] 10.1001/jama.2020.4783 PMC 바로가기 [Article Type] Research
CT quantification of pneumonia lesions in early days predicts progression to severe illness in a cohort of COVID-19 patientsResearch Paper Published on 2020-04-272022-10-28 Journal: Theranostics [Category] COVID-19, MERS, SARS, [키워드] 95% CI 95% confidence interval adjusted age and gender Algorithms artificial intelligence automatically calculated change characteristic Chest CT Clinical management Cohort collected Computed tomography consolidation coronavirus disease COVID-19 COVID-19 patient COVID-19 patients develop elevated feature Features Follow-up ground-glass opacity hazard ratio Health Hospital admission Logistic regression Lungs Neutrophil-to-lymphocyte ratio NLR Occurrence Patient patients percentage performed pneumonia lesion predict Predictive prognostic indicator progression PSV quantification Quantitative rationale representing Respiratory failure Result retrospective cohort retrospective cohort study risk severe illness Volume [DOI] 10.7150/thno.45985 PMC 바로가기 [Article Type] Research Paper
Surveillance of COVID-19 in the General Population Using an Online Questionnaire: Report From 18,161 Respondents in ChinaOriginal Paper Published on 2020-04-272022-10-31 Journal: JMIR Public Health and Surveillance [Category] COVID-19, SARS, [키워드] 95% CI advanced age analyzed approach change Characteristics China city Contact coronavirus coronavirus disease COVID-19 COVID-19 infection distribution early phase Factor Factors Fever General population higher risk history information International Lung disease objective online questionnaire outbreak pandemic participatory surveillance peaked Population potential risk Prevalence questionnaire R 2 report respondent Result returned risk Sex significantly Surveillance Syndromic surveillance the disease Wuhan [DOI] 10.2196/18576 PMC 바로가기 [Article Type] Original Paper