Evolutionary Analysis of Infectious Bronchitis Virus Reveals Marked Genetic Diversity and Recombination EventsArticle Published on 2020-05-292022-10-31 Journal: Genes [Category] Coronavirus, MERS, [키워드] affecting Analysis avian coronavirus bronchitis circulating Clustering collected disease Diversity domain Evolution functions Genetic Genotype genotypes globe help highlight IBV in viral Infectious Bronchitis Virus involved isolate Kingdom Lineage mechanism natural selection nine nucleocapsid outbreak PCR positive Protein real-time reverse transcriptase Recombination recombination event reported Result resulting Saudi Arabia selective pressure serotype Spread strain Strains vaccination Vaccine Vaccines virus viruses were used widespread [DOI] 10.3390/genes11060605 PMC 바로가기 [Article Type] Article
Broad-Spectrum Coronavirus Fusion Inhibitors to Combat COVID-19 and Other Emerging Coronavirus DiseasesReview Published on 2020-05-282022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome antibodies antibody antiviral drug approved caused characterized combat conserved coronavirus coronavirus disease COVID-19 Disadvantages Diseases drug drugs targeting Entry inhibitor fusion fusion inhibitor inhibitors MERS Middle East Novel coronavirus Other pathogen peptide Protease inhibitor protease inhibitors SARS Coronavirus SARS-CoV-2 syndrome Transmissibility Vaccine Vaccines [DOI] 10.3390/ijms21113843 PMC 바로가기 [Article Type] Review
Universal coronavirus vaccines: the time to start is nowComment Published on 2020-05-282022-10-30 Journal: NPJ Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome coronavirus coronavirus vaccine effort help Immunity Influenza Influenza virus International Novel coronavirus outbreak public health measure SARS-CoV-2 similarity Spread triggered Universal Vaccine Vaccine design Vaccine development Vaccines viral infection [DOI] 10.1038/s41541-020-0198-1 PMC 바로가기 [Article Type] Comment
Vaccines and Drug Therapeutics to Lock Down Novel Coronavirus Disease 2019 (COVID-19): A Systematic Review of Clinical TrialsInternal Medicine Published on 2020-05-282022-10-31 Journal: Cureus [Category] COVID-19, [키워드] 2019 novel coronavirus Antiviral approved BCG candidate cellular therapy Chinese Chloroquine clinical clinical trial Combination Compound conducted COVID 19 COVID-19 database deaths drug drug combination drug therapeutics effective healthcare ICTRP Infection information lock majority medication novel novel coronavirus disease observational study pandemic Phase I phase III trial registry responsible review sars-cov-2 (severe acute respiratory syndrome coronavirus -2) Stage tested therapeutic agent Therapeutics therapy Treatment treatment choices Trial Vaccine vaccine candidate Vaccines viral infection WHO [DOI] 10.7759/cureus.8342 PMC 바로가기 [Article Type] Internal Medicine
The non-specific and sex-differential effects of vaccinesArticle Published on 2020-05-272023-06-15 Journal: Nature reviews. Immunology [Category] MERS, SARS, [키워드] immunization Infectious diseases SARS-CoV-2 Vaccines [DOI] 10.1038/s41577-020-0338-x PMC 바로가기
Bioengineering tools to speed up the discovery and preclinical testing of vaccines for SARS-CoV-2 and therapeutic agents for COVID-19Review Published on 2020-05-272022-10-28 Journal: Theranostics [Category] COVID-19, MERS, SARS, [키워드] accelerate Antiviral antiviral drug bioengineering Cell Cell culture Community coronavirus COVID-19 Culture group identify International mechanism organoids Preclinical Testing provide Research SARS-CoV-2 SARS-COV-2 infection target therapeutic agent tissue Vaccine Vaccines [DOI] 10.7150/thno.47406 PMC 바로가기 [Article Type] Review
Challenges in Laboratory Diagnosis of the Novel Coronavirus SARS-CoV-2Review Published on 2020-05-262022-10-28 Journal: Viruses [Category] COVID-19, MERS, SARS, [키워드] Asymptomatic challenge Characteristics China Clinical treatment comprehensive strategy Coronavirus disease 2019 Coronavirus infection COVID-19 Critical Diagnosis diagnosis of COVID-19 diagnostic diagnostic challenges diagnostics gold standard highlight immunoassay Isolation Laboratory majority molecular testing novel outbreak Pandemics PCR performed POC point-of-care technology Research respiratory specimen rRT-PCR SARS-CoV-2 Sensitivity and specificity serology Spread Surveillance symptomatic patient Vaccines viral shedding virus viruses with COVID-19 Wuhan [DOI] 10.3390/v12060582 PMC 바로가기 [Article Type] Review
Certainty of success: three critical parameters in coronavirus vaccine developmentReview Article Published on 2020-05-252022-10-30 Journal: NPJ Vaccines [Category] COVID-19, [키워드] biological parameter certainty circulating coronavirus vaccine Coronavirus vaccines COVID-19 vaccine Critical death disease effective Efficacy force of infection humans Incubation period intensity pandemic parameter pathogen predicted Protective reduce SARS-CoV-2 SARS-COV-2 infection severity turn Vaccine Vaccine development Vaccines viral infection viral pathogen virus [DOI] 10.1038/s41541-020-0193-6 PMC 바로가기 [Article Type] Review Article
Why Challenge Trials of SARS‐CoV‐2 Vaccines Could Be Ethical Despite Risk of Severe Adverse EventsArticle Published on 2020-05-222023-06-18 Journal: Ethics & human research [Category] MERS, SARS, [키워드] coronavirus COVID‐19 Human challenge studies Randomized controlled trials Research Ethics Risk Taking Vaccines [DOI] 10.1002/eahr.500056 PMC 바로가기
Products in a Pandemic: Liability for Medical Products and the Fight against COVID-19Articles Published on 2020-05-202022-10-31 Journal: European Journal of Risk Regulation [Category] COVID-19, [키워드] arising Course COVID-19 effort equipment European examined Medicine pandemic Perspective produced product Protective rapid increase Regulatory response urgency Vaccines [DOI] 10.1017/err.2020.54 PMC 바로가기 [Article Type] Articles