accelerate – Page 32 – Communicable Diseases Research

An Update on Advances in COVID-19 Laboratory Diagnosis and Testing Guidelines in India

인도의 COVID-19 실험실 진단 및 테스트 지침의 발전에 대한 업데이트

Review

Published on 2021-03-042022-09-11
Journal: Frontiers in Public Health [Category] MERS, 변종, 진단,

miRCOVID-19: Potential Targets of Human miRNAs in SARS-CoV-2 for RNA-Based Drug Discovery

Article

Published on 2021-03-022022-10-30
Journal: Non-Coding RNA [Category] COVID-19,

[키워드] accelerate acute respiratory syndrome antagomir Anti-HCV anti-miR bind binding site coronavirus coronavirus disease COVID-19 COVID-19 pathogenesis drug Drug discovery drugs epithelial experimental validation expressed expression facilitate functional Genome HCV hepatitis C virus high affinity highlight Host Human human cell human miRNA humans identify immune cell type Interaction investigated knowledge mature miRNA Meta-analysis microRNA MicroRNAs miR-122 Miravirsen miRNA mRNA Pathogenesis Perspective Potential predicted Regulation reported RNA RNA genome RNA genomes RNA therapeutics RNA virus SARS-CoV-2 SARS-CoV-2 replication shown symptomatic target targets the SARS-CoV-2 the SARS-CoV-2 genome tissue Transcriptome treat Viral diseases viral RNAs viruses
[DOI] 10.3390/ncrna7010018 PMC 바로가기 [Article Type] Article

Impact of COVID-19 on Health Economics and Technology of Diabetes Care: Use Cases of Real-Time Continuous Glucose Monitoring to Transform Health Care During a Global Pandemic

COVID-19가 건강 경제학 및 당뇨병 관리 기술에 미치는 영향: 글로벌 팬데믹 기간 동안 건강 관리를 혁신하기 위한 실시간 연속 혈당 모니터링 사용 사례

Real-World Evidence of Real-Time CGM (rtCGM) Use and Healthcare Cost Implications

Published on 2021-03-012022-09-12
Journal: Diabetes technology & therapeutics [Category] Coronavirus, SARS, 진단,

[키워드] accelerate accelerated added addition Analysis Care change Community Continuous Continuous glucose monitoring coronavirus disease Course COVID-19 Critical database diabete diabetes Digital health economics Evidence example Glucose Government Health health economics Health technology highlight hospital Impact management monitoring pandemic Perspective public health remote monitoring representing Support technology telehealth The United States wrought
[DOI] 10.1089/dia.2020.0656 PMC 바로가기 [Article Type] Real-World Evidence of Real-Time CGM (rtCGM) Use and Healthcare Cost Implications

Phytochemicals against SARS-CoV as potential drug leads

잠재적 약물 리드로서 SARS-CoV에 대한 파이토케미컬

Article

Published on 2021-03-012022-09-11
Journal: Biomedical journal [Category] SARS, 신약개발,

[키워드] accelerate against SARS-CoV Analysis analyzed antiinflammatory antimalarial drug Antimalarial drugs Antiviral antiviral drug antiviral drugs assays cellular Cluster cluster analysis coronavirus CoV cysteine derivatives develop Developing drug Drug development drugs followed by health emergency Herbal herbal medicine in vitro information Lopinavir LOPINAVIR AND RITONAVIR MERS molecular docking natural natural products Pandemics pharmaceutical industry phytochemical protease reported researcher Ritonavir Safe SARS-CoV-2 SARS-CoV-2 strain Scientific community selected strain systematic review target
[DOI] 10.1016/j.bj.2020.12.002 PMC 바로가기 [Article Type] Article

A Proteome-Wide Immunoinformatics Tool to Accelerate T-Cell Epitope Discovery and Vaccine Design in the Context of Emerging Infectious Diseases: An Ethnicity-Oriented Approach

신종 전염병의 맥락에서 T-세포 에피토프 발견 및 백신 설계를 가속화하기 위한 프로테옴 전체 면역정보학 도구: 민족 중심 접근

Immunology

Published on 2021-02-262022-09-11
Journal: Frontiers in Immunology [Category] MERS, 유전자 메커니즘,

[키워드] accelerate Accuracy Analysis AUC build caused CD4+ T-cell CD8+ ChAdOx1 ChAdOx1 vaccine clinical trials comparable complicate Context contribute coronavirus country Coverage COVID-19 pandemic criteria disease distribution effective Emerging infectious disease Emerging infectious diseases emerging-infectious disease Epidemics epitope epitope clusters epitope density epitope discovery epitope mapping Epitope-based vaccine Epitopes Ethnic groups Ethnicity frequencies Frequency genetic polymorphisms geographic distributions glycoprotein HLA HLA allele HLA allele frequencies HLA allele frequency HLA alleles human leukocyte antigen immune response immune responses immune responsiveness immune system immunodominant immunoinformatics in silico Infectious diseases investigated Japanese leukocyte Mortality NetMHCpan optimization Pathogens peptide Phase III clinical trials polymorphism Population predicted protein antigen protein antigens proteome Region retrieved SARS-CoV-2 SARS-CoV-2 spike glycoprotein SARS-like coronavirus spike glycoprotein T-cell T-cell epitope T-cell epitopes the SARS-CoV-2 utility vaccination Vaccination strategy Vaccinations Vaccine vaccine candidates Vaccine design vaccine-induced immune response vaccine-induced immune responses Variability Variation virus
[DOI] 10.3389/fimmu.2021.598778 PMC 바로가기 [Article Type] Immunology

COVID-19 CG enables SARS-CoV-2 mutation and lineage tracking by locations and dates of interest

COVID-19 CG는 SARS-CoV-2 돌연변이 및 관심 위치 및 날짜별 혈통 추적을 가능하게 합니다.

Research Article

Published on 2021-02-232022-09-10
Journal: eLife [Category] MERS, 변종, 진단,

[키워드] accelerate adjust agency alarm Alter an area browser case studies cause change changes Characteristics clade clades collected coronavirus disease Coronavirus disease 2019 country CoV COVID-19 COVID-19 pandemic COVID-19 vaccine database develop diagnostic diagnostics dominant lineage effective effective vaccine Effective vaccines eLife Evolution faster feature genetic change genetic code genetic data genetic material geographical region GISAID database global effort global efforts help helping IMPROVE in viral information Intervention labor less Lineage lineages location Mutation mutation tracking mutations occur online tool open pandemic people with COVID-19 Primers provide public health public health agencies Public health interventions raised RBD RBD mutation Receptor binding domain reducing Research resource S477N SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 transmission scientist sensitivity single-nucleotide SNV SNVs Spread the SARS-CoV-2 therapeutic Therapeutics Treatment utility Vaccine Vaccines variant Variation Viral virus virus genome virus genomes virus mutation virus mutations
[DOI] 10.7554/eLife.63409 PMC 바로가기 [Article Type] Research Article

In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19

COVID-19의 혈청학적 진단을 위한 ELISA에서 SARS-CoV-2 특이적 B-세포 에피토프의 실리코 검출 및 검증

Article

Published on 2021-02-222022-09-10
Journal: Scientific Reports [Category] MERS, 진단, 치료기술,

[키워드] accelerate Antigen B-cell epitope Candidates Computational methods conducted COVID-19 database diagnosis of COVID-19 diagnostics disagreement ELISA ELISA plate Emerging infectious diseases Epidemiology epitope Epitopes FIVE fragment of help highest Inconclusive Infection Infectious disease Infectious diseases mixing N-terminal noise ratio nucleoprotein pathogen patients with SARS-CoV-2 plasma predict Protein Protein sequence analyses Rapid Receptor-binding domain Result RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 protein SARS-CoV-2 proteins sensitivity Sensitivity and specificity sequence sera serodiagnostic serological signal-to-noise ratio specificity Spike protein Spread structural biology the receptor-binding domain the spike protein viral infection
[DOI] 10.1038/s41598-021-83730-y PMC 바로가기 [Article Type] Article

The COVID-19 Pandemic: Disproportionate Thrombotic Tendency and Management Recommendations

Review

Published on 2021-02-182022-10-29
Journal: Tropical Medicine and Infectious Disease [Category] COVID-19,

[키워드] accelerate addition Anticoagulant Anticoagulants anticoagulation antiplatelet Antithrombotic antithrombotic therapy Biomarker caused Coagulopathies Coagulopathy complicate COVID-19 death develop direct-acting disease disproportionate Disseminated intravascular coagulation dose Endothelial dysfunction excessive inflammation incidence increased risk individual Infectious disease Inflammation Laboratory morbidity and mortality Patient platelet activation randomized clinical trials receive receiving resulting SARS-CoV-2 severe COVID-19 severity of COVID-19 spread of COVID-19 supportive care susceptible tendency therapeutic anticoagulation therapeutic intervention therapy Thromboembolic event thrombosis thrombotic Travel Treatment virus while with COVID-19
[DOI] 10.3390/tropicalmed6010026 PMC 바로가기 [Article Type] Review

COVID-19 trials: declarations of data sharing intentions at trial registration and at publication

COVID-19 시험: 시험 등록 및 출판 시 데이터 공유 의도 선언

Review

Published on 2021-02-182022-09-10
Journal: Trials [Category] MERS, 임상,

[키워드] accelerate Analysis analyzed caused COVID-19 effective eligible global pandemic greater help indicated Intention norm pandemic representing researcher response Result SARS-CoV-2 searched Seven Trial Trial registration trials unique
[DOI] 10.1186/s13063-021-05104-z PMC 바로가기 [Article Type] Review

Mapping major SARS-CoV-2 drug targets and assessment of druggability using computational fragment screening: Identification of an allosteric small-molecule binding site on the Nsp13 helicase

전산 단편 스크리닝을 사용한 주요 SARS-CoV-2 약물 표적 매핑 및 약물 가능성 평가: Nsp13 헬리카제의 알로스테릭 소분자 결합 부위 식별

Research Article

Published on 2021-02-172022-09-10
Journal: PLoS ONE [Category] MERS, 신약개발, 치료제,

[키워드] accelerate acting Antiviral benzene binding binding domain binding site calculated complex conformation conformational state conformational states drug target effective Efficiency effort FIVE free energy Free energy calculation Free energy calculations functional Helicase identification identify Impact information life Ligand ligand binding site mapping mechanism methyltransferase N-terminal Nsp12 nsp13 Protein protein-protein interaction recent replication-transcription complex RNA-dependent RNA polymerase S2 subunit SARS-CoV-2 SARS-CoV-2 drug small molecule Society solvent spike Spike protein Structural analysis target target protein the Spike was used Zinc
[DOI] 10.1371/journal.pone.0246181 PMC 바로가기 [Article Type] Research Article