Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia
글리신과 엽산은 선천적 철모구성 빈혈의 모델을 개선합니다.
Research Article
[키워드] 5-Ala
5-aminolevulinic acid
addition
Anemia
anemic
autosomal recessive
biosynthetic pathway
Blood
blood cell
Blood Transfusion
Cell
congenital
congenital sideroblastic anemia
derivative
determine
downstream
effective
exogenous glycine
exogenously
family member
folate
glycine
glycine cleavage system
Hem25
heme
heme biosynthetic pathway
heme synthesis
hemoglobin
homolog
humans
identify
inherited anemia
inherited anemias
iron
iron chelation
knowledge
metabolite
Mitochondria
mitochondrial
mitochondrial glycine importer
mitochondrial glycine importers
mitochondrial glycine transporter
mitochondrial glycine transporters
Model
molecular
Mutation
Patient
precursors
Protein
red blood cell
red blood cells
required
restore hemoglobin level
restore hemoglobin levels
Safe
sideroblastic anemia
Sideroblastic anemias
SLC25
SLC25A38
synthesis
the disease
Tolerability
Treatment
Vitamin
while
yeast
yeast cell
yeast cells
Ymc1
zebrafish
[DOI] 10.1371/journal.pgen.1005783 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1005783 PMC 바로가기 [Article Type] Research Article