General practitioner visits after SARS-CoV-2 omicron compared with the delta variant in children in Norway: a prospective nationwide registry studyArticle Published on 2022-08-012022-11-16 Journal: BMJ Paediatrics Open [Category] SARS, 변종, [키워드] appear Care children Contact COVID-19 Effect fixed general practitioner healthcare increase in Infection Interaction less logistic regressions Norway Omicron variant outcome positive Positive test primary care returned SARS-CoV-2 SARS-COV-2 infection Sociodemographic factor Study design study population tested variant virus virus variant [DOI] 10.1136/bmjpo-2022-001502 PMC 바로가기
T-cell responses to SARS-CoV-2 Omicron spike epitopes with mutations after the third booster dose of an inactivated vaccine비활성화 백신의 세 번째 추가 접종 후 돌연변이가 있는 SARS-CoV-2 오미크론 스파이크 에피토프에 대한 T 세포 반응Article Published on 2022-08-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration Antibody Response Antibody responses booster dose booster vaccination conserved CoronaVac coronavirus dose elicited enhancement Epitopes escape estimate evaluated Impact Inactivated vaccine individual individuals Infection mononuclear cell mononuclear cells Mutation mutations omicron Omicron variant participant Participants PBMCs peptide peptides Peripheral blood Peripheral blood mononuclear cells Protective respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus significantly spike epitope Spike protein Spike proteins stimulate T-cell T-cell activation T-cell Response T-cell responses the SARS-CoV-2 the spike protein Vaccine Vaccines variant virus volunteers weakened were used [DOI] 10.1002/jmv.27814 PMC 바로가기 [Article Type] Article
Association of Receiving a Fourth Dose of the BNT162b Vaccine With SARS-CoV-2 Infection Among Health Care Workers in Israel이스라엘 의료 종사자들 사이에서 SARS-CoV-2 감염 BNT162b 백신 4차 접종 협회Multicenter Study Published on 2022-08-012022-09-11 Journal: JAMA Network Open [Category] SARS, 변종, [키워드] 95% CI adjusted hazard ratio age Analysis benefit BNT162b BNT162b2 BNT162b2 vaccine both groups Breakthrough infection Chain Reaction cohort study COVID-19 COVID-19 infection COVID-19 infections Cox proportional hazard Critical death dose evaluate female hazard ratio HCW HCWs Health care Health care worker health care workers hospital Hospital staff infection rate medical staff Ministry of Health mitigate multicenter cohort study occurred omicron Omicron variant outcome polymerase chain polymerase chain reaction Polymerase chain reaction test positive receiving recipient reduced reduction Regression model Relative risk risk SARS-CoV-2 severe disease Symptom test result tested vaccination vaccination rate Vaccine vaccine dose variant was performed worker [DOI] 10.1001/jamanetworkopen.2022.24657 PMC 바로가기 [Article Type] Multicenter Study
Diminished T-cell immune responses to SARS-CoV-2 omicron variant after BNT162b2 vaccinationBNT162b2 백신 접종 후 SARS-CoV-2 오미크론 변이체에 대한 T 세포 면역 반응 감소Article Published on 2022-08-012022-09-11 Journal: Immunology letters [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] BNT162b2 diminished Omicron variant SARS-CoV-2 T-cell immune response vaccination [DOI] 10.1016/j.imlet.2022.07.004 PMC 바로가기 [Article Type] Article
Effectiveness Associated With BNT162b2 Vaccine Against Emergency Department and Urgent Care Encounters for Delta and Omicron SARS-CoV-2 Infection Among Adolescents Aged 12 to 17 Years12~17세 청소년의 Delta 및 Omicron SARS-CoV-2 감염에 대한 응급실 및 긴급 치료에 대한 BNT162b2 백신과 관련된 효과Article Published on 2022-08-012022-09-11 Journal: JAMA Network Open [Category] SARS, 변종, 진단, 치료법, [키워드] 95% CI Acute respiratory infection adjusted analyses Adolescent Against age BNT162b2 booster Care case-control study Chain Reaction children conducted COVID-19 vaccine Delta delta variant Department dose doses Effectiveness Electronic health record Electronic health records Emergency emergency department encounter evaluate Health Health care Health care system help highest IQR median of BNT162b2 omicron Omicron variant Omicron variants outcome outcomes participant Polymerase chain reaction test recommendation registry data respiratory infection SARS-CoV-2 SARS-COV-2 infection tested vaccination Vaccination Status Vaccine variant variants variants of SARS-CoV-2 waned Year [DOI] 10.1001/jamanetworkopen.2022.25162 PMC 바로가기 [Article Type] Article
A fourth dose of Omicron RBD vaccine enhances broad neutralization against SARS-CoV-2 variants including BA.1 and BA.2 in vaccinated miceOmicron RBD 백신의 네 번째 용량은 백신 접종된 마우스에서 BA.1 및 BA.2를 포함한 SARS-CoV-2 변이체에 대한 광범위한 중화를 향상시킵니다.Article Published on 2022-08-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Antibody Response booster build COVID-19 pandemic cross-reactive demonstrated dose elicited ENhance escaped evaluated immunization induce mice NAb NAbs neutralization Neutralizing activity Neutralizing antibodies neutralizing antibody omicron Omicron variant RBD RBD vaccine SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 vaccines SARS-CoV-2 variant SARS-CoV-2 variants sequential immunization. strain triggered Vaccine Vaccines variant was used [DOI] 10.1002/jmv.27811 PMC 바로가기 [Article Type] Article
Insights into the structural peculiarities of the N-terminal and receptor binding domains of the spike protein from the SARS-CoV-2 Omicron variantSARS-CoV-2 Omicron 변이체의 스파이크 단백질 N-말단 및 수용체 결합 도메인의 구조적 특성에 대한 통찰력Article Published on 2022-08-012022-09-11 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 변종, [키워드] Accessibility ACE2 addition Analysis antibody B.1.1.529 BA.1) binding binding domain binding efficiency changes in computational analysis COVID-19 COVID-19 vaccines Effect Epitopes evaluated free energy glycan glycans higher infectivity insight Interaction mAb molecular dynamics molecular dynamics simulations Mutation N-terminal N-terminal domain N-terminal domain (NTD) Neutralizing NTD NTDs omicron Omicron (B.1.1.529 Omicron variant performed Protein provide raised RBD RBD domain RBDs Receptor binding domain receptor binding domain (RBD) reduce reducing residue SARS-CoV-2 specific antibodies Spike protein stability the RBD the SARS-CoV-2 the spike protein variant variant of SARS-CoV-2 Wuhan [DOI] 10.1016/j.compbiomed.2022.105735 PMC 바로가기 [Article Type] Article
Rapid syndromic testing for respiratory viral infections in children attending the emergency department during COVID-19 pandemic in Lille, France, 2021-20222021-2022년 프랑스 릴에서 COVID-19 전염병 동안 응급실에 다니는 어린이의 호흡기 바이러스 감염에 대한 신속한 증후군 검사Article Published on 2022-08-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Alpha variant both groups children circulation collected COVID-19 pandemic Delta disease Emergency emergency department enterovirus France Genome sequencing hospital Human Human rhinovirus in both groups Infection intensive care intensive care unit majority median median age molecular MOST multiplex Mutation nasopharyngeal swabs non-specific omicron Omicron variant Omicron variants Other Other respiratory viruses outpatients Panel Patient PCR-based assay pediatric positive Prevalence prevalent ranged Rapid respiratory respiratory infection respiratory infections respiratory syncytial virus respiratory viral infection respiratory virus respiratory viruses rhinovirus Sample SARS-CoV-2 SARS-CoV-2 infected patient SARS-CoV-2 infected patients SARS-COV-2 infection SARS-CoV-2 positivity SARS-CoV-2 variant screened severe disease significant increase Symptoms syndromic testing treated variant variants viral infections viral respiratory infections was performed [DOI] 10.1016/j.jcv.2022.105221 PMC 바로가기 [Article Type] Article
The influence of new SARS-CoV-2 variant Omicron (B.1.1.529) on vaccine efficacy, its correlation to Delta variants: A computational approach새로운 SARS-CoV-2 변이체 Omicron(B.1.1.529)이 백신 효능에 미치는 영향, Delta 변이체와의 상관관계: 전산적 접근Article Published on 2022-08-012022-09-11 Journal: Microbial pathogenesis [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] addition Analysis antibody approach AY.1 B.1.1.529 binding affinity caused computational analysis correlation COVID CR3022 Delta Delta variants docking docking analysis domain Effect Efficacy Host hosts human ACE2 receptor human monoclonal antibodies Human monoclonal antibody immune evasion in silico Approach In-silico analysis Interaction lead MD simulation Modification Mutation neutralizing antibody new SARS-CoV-2 omicron Omicron variant pathogenicity promote Proteins RBD RBD variant Reinfection SARS-CoV-2 variant Spike proteins Strains Structure the binding affinity the WHO Vaccine variant [DOI] 10.1016/j.micpath.2022.105619 PMC 바로가기 [Article Type] Article
Therapeutics to tackle Omicron outbreak오미크론 발병에 대처하는 치료제Article Published on 2022-08-012022-09-11 Journal: Immunotherapy [Category] COVID19(2023년), SARS, 변종, [키워드] Abstract convalescent convalescent plasma COVID-19 monoclonal monoclonal antibody Mutation omicron Omicron variant outbreak SARS-CoV-2 Therapeutics variant [DOI] 10.2217/imt-2022-0064 PMC 바로가기 [Article Type] Article