RCT – Page 32 – Communicable Diseases Research

Interventions to reduce social isolation and loneliness during COVID-19 physical distancing measures: A rapid systematic review

Research Article

Published on 2021-02-172022-10-28
Journal: PLoS ONE [Category] Coronavirus, MERS,

Prospective meta-analysis protocol on randomised trials of renin-angiotensin system inhibitors in patients with COVID-19: an initiative of the International Society of Hypertension

COVID-19 환자를 대상으로 한 레닌-안지오텐신계 억제제의 무작위 시험에 대한 전향적 메타분석 프로토콜: 국제고혈압 학회(International Society of Hypertension)의 주도

Article

Published on 2021-02-162022-08-31
Journal: BMJ Open [Category] meta-analysis, 임상,

[키워드] ACE inhibitor ACE inhibitors ACEi ACEi/ARB Admission all-cause mortality Analysis Angiotensin II approval ARB ARBs Cardiology cardiovascular event Cardiovascular events clinical decision Comorbidities contribute Controlled controlled trials country COVID-19 Decision making drug Efficacy eligible Ethics Ethnicity Follow-up followed by Formal Guidance Health policy hypertension identify include inclusion criteria infected with SARS-CoV-2 Informed consent inhibitor initiated intensive care mechanical ventilation Meta-analysis occur outcome Patient patients with COVID-19 peer-reviewed performed Primary outcome Prospective protocol public health randomised randomised controlled trial Randomised controlled trials Randomised trial RCT RCTs receptor receptor blocker recruitment renin-angiotensin system responsibility secondary Secondary outcomes smoking smoking status Society study duration therapy Trial widespread
[DOI] 10.1136/bmjopen-2020-043625 PMC 바로가기 [Article Type] Article

Convalescent plasma is a clutch at straws in COVID-19 management! A systematic review and meta-analysis

회복기 혈장은 COVID-19 관리에서 빨대에 클러치입니다! 체계적인 검토 및 메타 분석

Meta-Analysis

Published on 2021-02-012022-09-11
Journal: Journal of medical virology [Category] Fulltext, MERS, 임상,

[키워드] 95% CI absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Case series case sery clinical condition clinical conditions Clinical improvement clinically Cohort studies conducted control group Controlled trial convalescent plasma Convalescent plasma therapy coronavirus coronavirus disease Coronavirus-2 COVID-19 COVID-19 patient COVID-19 patients Critical database dosage Effectiveness evaluate Evidence FIVE IMPROVE increase meta-analyses Meta-analysis Mortality patients patients with COVID-19 plasma randomized control trial Randomized controlled trials RCT RCTs reduce reducing mortality reduction reported required respiratory retrieved robust safety margin Seven severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 systematic review therapeutic option therapy titre Viral viral clearance viral shedding
[DOI] 10.1002/jmv.26408 PMC 바로가기 [Article Type] Meta-Analysis

Corticosteroids for Patients With Coronavirus Disease 2019 (COVID-19) With Different Disease Severity: A Meta-Analysis of Randomized Clinical Trials

질병 중증도가 다른 코로나바이러스 질병 2019(COVID-19) 환자를 위한 코르티코스테로이드: 무작위 임상 시험의 메타 분석

Meta-Analysis

Published on 2021-02-012022-09-11
Journal: Journal of cardiothoracic and vascular anesthesia [Category] 임상,

[키워드] 2019-nCoV 2019-nCoV infection Adult patients clinical confidence interval Control coronavirus coronavirus disease Corticosteroid Corticosteroids corticosteroids therapy COVID-19 Critically ill Critically ill patient critically ill patients disease severity evaluate the effect hospital hypoxemic increased mortality Infection intensive care units Large randomized clinical trials measurement mechanical ventilation mechanically ventilated meta-analyses Meta-analysis Mortality mortality rate nCoV Novel coronavirus overall mortality oxygen Oxygen therapy Patient patients treated primary endpoint randomized clinical trial RCT RCTs Relative risk risk significantly lower statistically significant subgroup subgroup of patient survival Test treat treated Treatment Trial use of corticosteroids was performed with COVID-19
[DOI] 10.1053/j.jvca.2020.11.057 PMC 바로가기 [Article Type] Meta-Analysis

Research response to coronavirus disease 2019 needed better coordination and collaboration: a living mapping of registered trials

2019년 코로나바이러스 질병에 대한 연구 대응은 더 나은 조정과 협력이 필요했습니다: 등록된 시험의 살아있는 매핑

Article

Published on 2021-02-012022-09-11
Journal: Journal of clinical epidemiology [Category] 임상,

[키워드] activity Analysis clinical clinical trial coronavirus disease Coronavirus disease 2019 country Course COVID-19 COVID-19 epidemic evaluated expected first RCT highest Hydroxychloroquine Intervention Italy Living mapping Meta-analysis MOST pandemic patients performed Planning platform prevention preventive intervention preventive interventions Randomized controlled trial Randomized controlled trials RCT RCTs recorded regimen Registered registry Research Research question Sample size small sample size systematic review the epidemic the median The United States the WHO therapeutic intervention Treatment treatments for COVID-19 Trial United States WHO International Clinical Trials Registry Platform
[DOI] 10.1016/j.jclinepi.2020.10.010 PMC 바로가기 [Article Type] Article

Effectiveness of remdesivir for the treatment of hospitalized COVID-19 persons: A network meta-analysis

코로나19 입원환자 치료에 렘데시비르의 효과: 네트워크 메타분석

Meta-Analysis

Published on 2021-02-012022-08-31
Journal: Journal of medical virology [Category] meta-analysis, 치료제,

[키워드] 95% CI 95% confidence interval Abstract abstracts blinded clinical benefit clinical benefits Clinical improvement clinical recovery clinical trials conducted coronavirus coronavirus disease coronavirus disease-2019 COVID-19 database Effectiveness evaluated Evidence follow-up period higher odd higher odds hospitalized COVID-19 improvement inception investigated Meta-analysis Network meta-analysis NMA NMAs Odds ratio Open-label outcome outcomes Placebo Probability random effect randomization randomized clinical trial RCT RCTs recovery regimen Relative risk Remdesivir researcher risk screened Treatment
[DOI] 10.1002/jmv.26443 PMC 바로가기 [Article Type] Meta-Analysis

Serious Concerns About the RCT Study Quality of Traditional Chinese Medicine Injections for Treating Cardiovascular Diseases and COVID-19

심혈관 질환 및 COVID-19 치료를 위한 한약 주사제의 RCT 연구 품질에 대한 심각한 우려

Article

Published on 2021-02-012022-09-11
Journal: Cardiovascular Drugs and Therapy [Category] 임상,

[키워드] cardiovascular Chinese concern COVID-19 Medicine Quality RCT Traditional treating
[DOI] 10.1007/s10557-020-07053-2 PMC 바로가기 [Article Type] Article

Dental Anxiety, Fear, and Root Canal Treatment Monitoring of Heart Rate and Oxygen Saturation in Patients Treated during the Coronavirus Disease 2019 Pandemic: An Observational Clinical Study

Observational Study

Published on 2021-02-012022-10-05
Journal: Journal of endodontics [Category] SARS, 임상,

[키워드] acute respiratory syndrome Anxiety Blood Canal clinical confinement period coronavirus Coronavirus disease 2019 correlation demographic dental dental anxiety disease distribution elevated Endodontics evaluate evaluated fear Frequency group heart heart rate Interaction interquartile range IQR Kruskal-Wallis test Mann-Whitney Mann-Whitney test median MONITOR monitoring oximetry Oxygenation Patient patients patients treated performed postoperative Rate RCT Registered required root root canal saturation scale selected severe acute respiratory syndrome coronavirus 2 Spearman treated Treatment variable was increased were used
[DOI] 10.1016/j.joen.2020.10.024 PMC 바로가기 [Article Type] Observational Study

Remdesivir for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials

코로나19 치료를 위한 렘데시비르: 무작위 대조 시험의 체계적인 검토 및 메타 분석

Meta-Analysis

Published on 2021-02-012022-09-11
Journal: Contemporary clinical trials [Category] 임상, 치료법, 치료제,

[키워드] adverse event antiviral therapies antiviral therapy both groups certainty certainty of evidence Clinical improvement ClinicalTrials Cochrane Library control group COVID-19 database death discharged patient Efficacy and safety Evidence Follow-up hospital discharge independent investigator Meta-analysis moderate Mortality no significant difference nucleotide patients with COVID-19 performed Placebo randomization Randomized controlled trial Randomized controlled trials RCT RCTs recovered patient recovered patients reduction in Remdesivir risk risk difference SARS-CoV-2 searched Serious Adverse Event Serious Adverse Events significant decrease Standard of care standardized mean difference systematic review tested Treatment
[DOI] 10.1016/j.cct.2021.106272 PMC 바로가기 [Article Type] Meta-Analysis

High-dose corticosteroid pulse therapy increases the survival rate in COVID-19 patients at risk of hyper-inflammatory response

고용량 코르티코스테로이드 펄스 요법은 과염증 반응의 위험이 있는 COVID-19 환자의 생존율을 증가시킵니다

Research Article

Published on 2021-01-282022-08-13
Journal: PLoS ONE [Category] Biochemistry, COVID-19,

[키워드] Analysis C-reactive protein can be used carried co-morbidities co-morbidity Corticosteroid corticosteroid pulse Course COVID-19 COVID-19 patient D-dimer decrease decreased mortality determine Dexamethasone Diagnostic Criteria effective intervention Efficacy ferritin following Future HDCPT High dose high dose corticosteroid pulse therapy hyper-inflammatory response identify IL-6 inclusion criteria increase increased survival initial Laboratory Lactate lactate dehydrogenase marker Methylprednisolone morbidities Mortality multivariate Cox regression Non-survivors objective observational study parameter Patient patients pro-inflammatory pro-inflammatory markers prospective observational study randomized clinical trial RCT Result risk statistically significant Stratification survival rate survival rates survivor Test the patient Therapies therapy to define treated
[DOI] 10.1371/journal.pone.0243964 PMC 바로가기 [Article Type] Research Article