Lateral flow–based nucleic acid detection of SARS-CoV-2 using enzymatic incorporation of biotin-labeled dUTP for POCT usePOCT 사용을위한 비오틴-표지 된 DUTP의 효소 혼입을 사용하여 SARS-COV-2의 측면 유동 기반 핵산 검출Communication Published on 2022-01-192022-09-01 Journal: Analytical and bioanalytical chemistry [Category] COVID19(2023년), Fulltext, SARS, 진단, 치료기술, [키워드] Abstract Accuracy Biotin cDNA Combination COVID-19 COVID-19 pandemic Data analysis detrimental effect detrimental effects develop diagnostic effort FITC immunochromatographic incorporation indicate isothermal isothermal amplification LAMP Lateral lateral flow Lateral flow assay (LFA) Loop-mediated isothermal amplification N-gene nucleic acid nucleic acid amplification Nucleic acid detection overcome Pandemics Pathogens POCT point of care Point of care testing (POCT) positive primer Rapid reduced Research research and development reverse transcriptase Reverse transcription loop-mediated isothermal amplification (RT-LAMP) RNA sample RNA samples RT-LAMP SARS-CoV-2 SARS-CoV-2 viral RNA SARS-CoV-2 N-gene semi-quantitative sensitive sensitivity Specific specificity supplementary material tested Viral Viral RNA [DOI] 10.1007/s00216-022-03880-4 PMC 바로가기 [Article Type] Communication
Single-dose SARS-CoV-2 vaccinations with either BNT162b2 or AZD1222 induce disparate Th1 responses and IgA productionBNT162B2 또는 AZD1222를 사용한 단일 용량 SARS-COV-2 백신 접종Research Article Published on 2022-01-192022-09-01 Journal: BMC Medicine [Category] SARS, 진단, [키워드] A significant reduction acute respiratory syndrome adaptive analyzed Anti-inflammatory antibody Antigen AZD1222 BNT162b2 change COVID-19 Cytotoxic T cells disparate dominant early immune response early immune responses Effectiveness effector T cell effector T cells elicited IgA IgG IgM and IgG Immune cell immune priming immune responses Impact induce isotype leukopenia priming respiratory Result SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 vaccination seronegative participant severe acute respiratory syndrome virus single dose Single-dose Spike protein Stimulation subpopulations supplementary material T cell T cell response T cells Th1 response type 1 helper Type 1 helper T cells vaccination Vaccine vaccinees virus while [DOI] 10.1186/s12916-022-02240-4 PMC 바로가기 [Article Type] Research Article
COVID-19 myth-busting: an experimental studyRandomized Controlled Trial Published on 2022-01-192022-10-04 Journal: BMC Public Health [Category] SARS, 임상, [키워드] age and gender assigned attrition baseline correction COVID-19 effective Effectiveness Effects Health identify infodemic Intervention misinformation myth Myth busting Myth correction participant post-intervention public health random Randomly reduce Replication Result shown significantly lower supplementary material tested website [DOI] 10.1186/s12889-021-12464-3 PMC 바로가기 [Article Type] Randomized Controlled Trial
Association between COVID-19 vaccine hesitancy and generalized trust, depression, generalized anxiety, and fear of COVID-19Research Published on 2022-01-182022-10-28 Journal: BMC Public Health [Category] COVID-19, SARS, [키워드] analyses Analysis Anxiety asked association conducted covariates COVID-19 COVID-19 vaccination COVID-19 vaccine Depression Fear of COVID-19 Generalized Generalized anxiety Generalized trust Japan less mental health condition moderate multinomial logistic regression outcome participant predictor response Result severe depression Sociodemographic supplementary material vaccinated against COVID-19 Vaccine hesitancy variable variables were used [DOI] 10.1186/s12889-021-12479-w PMC 바로가기 [Article Type] Research
COVID-19 vaccine literacy in patients with systemic autoimmune diseasesArticle Published on 2022-01-182022-10-31 Journal: Current Psychology (New Brunswick, N.j.) [Category] COVID-19, [키워드] age Area association Attitudes Autoimmune disease Autoimmune diseases beliefs benefit Characteristics conducted contribute country COVID-19 COVID-19 vaccination COVID-19 vaccine cross-sectional determinant evaluate evaluated Factor female functional Gender highest infodemic insight Italian literacy male medium Patient required risk Significant Sociodemographic characteristics supplementary material systemic autoimmune disease Systemic autoimmune diseases vaccination Vaccine vaccine literacy [DOI] 10.1007/s12144-022-02713-y PMC 바로가기 [Article Type] Article
Examining COVID-19 vaccine uptake and attitudes among 2SLGBTQ+ youth experiencing homelessnessResearch Published on 2022-01-182022-10-28 Journal: BMC Public Health [Category] COVID-19, SARS, [키워드] 2SLGBTQ+ youth approach COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines demographic characteristics Descriptive statistics exacerbated Examining facilitator Gender identity Greater Toronto Area Health Health Service Healthcare system highlight homelessness impacted information Interpretation iterative lack majority mental health Mixed-methods objective organization pandemic participated provided public health public health messaging qualitative data recruited Result sexual orientation Side effects solution statistical test supplementary material the vaccine Vaccine variable was used were used [DOI] 10.1186/s12889-022-12537-x PMC 바로가기 [Article Type] Research
The ongoing impact of Covid-19 pandemic on children with medical complexity: the experience of an Italian pediatric palliative care networkResearch Published on 2022-01-182022-10-29 Journal: Italian Journal of Pediatrics [Category] COVID-19, SARS, [키워드] addressed Administered caused children COVID-19 COVID-19 pandemic criteria eligible European country examined Frequency health facilities healthcare services Home assistance Impact impacted introduced investigated Italian Italian language Italy knowledge lockdown measure network outbreak Palliative care pandemic Patient pediatric Pediatric palliative care questionnaire reduced reduction in Result retrospective returned SARS-CoV-2 significantly supplementary material Support was reduced [DOI] 10.1186/s13052-022-01206-9 PMC 바로가기 [Article Type] Research
Airway management for one lung ventilation during COVID-19 pandemic: a survey within Italian anesthesiologistsOriginal Article Published on 2022-01-182022-10-30 Journal: Journal of Anesthesia, Analgesia and Critical Care [Category] COVID-19, [키워드] Aerosol generating procedures airway airway management anesthesiologist bronchial blocker Bronchial blockers changes in Clinical practice Complete complex COVID-19 COVID-19 pandemic diffusion group high risk hospital infection risk invasive Italian lung Lung separation management mandatory National outbreak over participant Personal protective equipment Protective questionnaire recognize Responder Result reveal risk SARS-CoV-2 SARS-COV-2 infection sequence submitted supplementary material Thoracic thoracic anesthesia Variability Ventilation virus [DOI] 10.1186/s44158-021-00029-0 PMC 바로가기 [Article Type] Original Article
Activation of TCA cycle restrains virus-metabolic hijacking and viral replication in mouse hepatitis virus-infected cellsResearch Published on 2022-01-182022-11-01 Journal: Cell & Bioscience [Category] COVID-19, [키워드] activate Activation acute respiratory syndrome caused Cell cellular coronavirus coronavirus disease COVID-19 Efficacy endogenous Fatty acid fatty acids Glutamine Glycolysis Host Infection inhibitor Intervention introduced investigated metabolism metabolite MHV Mitochondria mitochondrial metabolism mouse hepatitis mouse hepatitis virus NAD+ nicotinamide riboside NR pandemic pyruvate Replication reported Result SARS-CoV-2 significantly supplementary material suppress suppresse suppressed survival TCA cycle therapeutic Therapeutic molecule therapy for COVID-19 Transport viral replication virus virus-infected cell [DOI] 10.1186/s13578-021-00740-z PMC 바로가기 [Article Type] Research
Evaluation of early complications, outcome, and mortality in Coronavirus Disease 2019 (COVID-19) infection in patients who underwent orthopedic surgeryResearch Published on 2022-01-182022-10-27 Journal: BMC Musculoskeletal Disorders [Category] COVID-19, [키워드] average Complication complications confidence COVID-19 COVID-19 patient death Evidence Frequency high-risk patient Hospitalization ICU admission Infection less Level moderate morbidity morbidity and mortality Mortality mortality rate occurred Odds ratio orthopedic Orthopedic procedures outcome Patient patients with COVID-19 patients without COVID-19 postoperative prospective cohort study reduce reported Respiratory failure Result severe pulmonary involvement significantly higher Society suggested supplementary material surgical threshold Ventilation were excluded were recorded [DOI] 10.1186/s12891-022-05010-8 PMC 바로가기 [Article Type] Research