Rationale for the Use of Radiation-Activated Mesenchymal Stromal/Stem Cells in Acute Respiratory Distress Syndrome급성 호흡곤란 증후군에서 방사선 활성화 중간엽 간질/줄기세포 사용의 근거Review Published on 2020-09-022022-09-11 Journal: Cells [Category] SARS, 비임상, [키워드] activated acute respiratory-distress syndrome alleviate Analysis Annexin annexin A1 ARDS breath caused Cell Cell therapy cells characteristic Combination conditions COVID-19 dramatic increase Exosome Exosomes experimental radiotherapy greater Hypothesis hypothetical hypoxia IMPROVE Inflammation intensive care intensive care unit life-threatening load mesenchymal cells Mesenchymal stem cells Metastasis mice microvesicle Microvesicles MSC MSCs Patient Pneumonia Protein Proteins proteomic Proteomic analysis Radiation radiobiology Radiotherapy rationale reduce released respiratory respiratory capacity SARS-CoV-2 secreted shown significant difference significantly stimulated Symptom the cells therapeutic strategy therapy transplantation Tumor [DOI] 10.3390/cells9092015 PMC 바로가기 [Article Type] Review
Cytokine Storm in COVID-19: “When You Come Out of the Storm, You Won’t Be the Same Person Who Walked in”Immunology Published on 2020-09-022022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress Asymptomatic cause concerning coronavirus courses COVID-19 Cytokine storm Cytokines forms host immune system induce Inflammation manifestation Novel coronavirus pandemic Pathogenesis Person Potential treatment proinflammatory responsible SARS-CoV-2 SARS-CoV2 severe respiratory infection severity storm syndrome translation [DOI] 10.3389/fimmu.2020.02132 PMC 바로가기 [Article Type] Immunology
Evidence for possible association of vitamin D status with cytokine storm and unregulated inflammation in COVID-19 patientsOriginal Article Published on 2020-09-022022-10-28 Journal: Aging Clinical and Experimental Research [Category] COVID-19, MERS, SARS, [키워드] 25-hydroxyvitamin D 95% CI 95% confidence interval a metric adaptive association average C-reactive protein C-reactive protein (CRP calculated Case mortality ratio Complication Concentration confirmed case country COVID-19 COVID-19 mortality COVID-19 patient COVID-19 patients CRP cytokine production Cytokine storm Deceased deficiency determine Evidence healthy subject individual Inflammation investigated Mortality objective Odds ratio Patient prevalence of COVID-19 reducing Result SARS-CoV-2 screening strategy severe COVID-19 severe COVID-19 patient severe COVID-19 patients the mean Vitamin D Vitamin D status was used [DOI] 10.1007/s40520-020-01677-y PMC 바로가기 [Article Type] Original Article
COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City Research Published on 2020-09-022022-10-05 Journal: Modern pathology : an official journal of the Unit [Category] SARS, 진단, [키워드] acute respiratory distress airway epithelium airways alveolar alveolar damage Autopsy Cohort conditions contribute correlated COVID-19 Culture cytoplasmic DAD determine Diagnosis diffuse disease endothelial evaluated feature Features female global pandemic heterogeneous histologic hyaline membranes IHC immunohistochemistry independent Infection Inflammation initial Injury intubation involved Italy less lung lung damage male median age membrane Microscopy microthrombi Mortality New York City Patient Platelet Pneumocytes Pneumonia positive RNA SARS-CoV-2 SARS-CoV-2 viral small vessel Spike protein subset syndrome three centers Tracheobronchitis USA vacuolization Vascular injury vasculature vessel viral culture virus was performed [DOI] 10.1038/s41379-020-00661-1 [Article Type] Research
Neutrophil-to-Lymphocyte Ratios Are Closely Associated With the Severity and Course of Non-mild COVID-19Immunology Published on 2020-09-022022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Admission analyzed association cardiovascular disease CD3 CD8 Clinical characteristics Clinical data conducted coronavirus coronavirus disease Course COVID-19 Cytokines discharge disease course evaluated Factor first test identify IL-10 IL-6 Illness severity immune damage in-depth analysis Infection Inflammation Inflammatory cytokines information Logistic regression Male sex marker measure Neutrophil-to-lymphocyte ratio Neutrophil-to-lymphocyte ratios objective pathological mechanism Patient positively correlated predict pulse Ratio recruited Result risk factor SARS-CoV-2 severity severity and course of non-mild COVID-19 significantly subset T lymphocyte the disease underlying disease was collected Wuhan [DOI] 10.3389/fimmu.2020.02160 PMC 바로가기 [Article Type] Immunology
Thrombin Inhibition by Argatroban: Potential Therapeutic Benefits in COVID-19Review Published on 2020-09-012023-06-16 Journal: Cardiovascular Drugs and Therapy [Category] MERS, SARS, [키워드] argatroban Coagulopathy COVID-19 Inflammation SARS-CoV-2 [DOI] 10.1007/s10557-020-07066-x PMC 바로가기 [Article Type] Review
Lung involvement in macrophage activation syndrome and severe COVID-19: results from a cross-sectional study to assess clinical, laboratory and artificial intelligence-radiological differencesComparative Study Published on 2020-09-012023-06-19 Journal: Annals of the rheumatic diseases [Category] Fulltext, SARS, [키워드] arthritis, juvenile Inflammation still's disease, adult-onset. [DOI] 10.1136/annrheumdis-2020-218048 PMC 바로가기 [Article Type] Comparative Study
COVID-19 is, in the end, an endothelial diseaseReview Published on 2020-09-012023-06-19 Journal: European heart journal [Category] Fulltext, SARS, [키워드] cytokine Endothelium Inflammation microvasculature thrombosis [DOI] 10.1093/eurheartj/ehaa623 PMC 바로가기 [Article Type] Review
Nicotine and the nicotinic cholinergic system in COVID-19COVID-19의 니코틴과 니코틴 콜린성 시스템Review Published on 2020-09-012022-09-12 Journal: The Febs Journal [Category] MERS, SARS, 진단, [키워드] ACE2 agonists allosteric modulators Anti-inflammatory caused Comorbidities COVID-19 COVID-19 pathology COVID-19 progression disease Diseases drug Effect effective effort exacerbate hypothese Inflammation Interaction nAChR neurodegenerative Neuropsychiatric Nicotine offered pandemic Patient positive receptor reduction Regulation Replication SARS-CoV-2 SARS-CoV-2 entry smoking Support therapeutic Treatment variety virus with COVID-19 [DOI] 10.1111/febs.15521 PMC 바로가기 [Article Type] Review
Parotitis-Like Symptoms Associated with COVID-19, France, March–April 2020Research Letter Published on 2020-09-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, SARS, [키워드] clinical feature clinical picture coronavirus disease COVID-19 France Inflammation magnetic resonance imaging Neck node Occurrence parotid parotitis Patient respiratory infections Result salivary glands SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Support viruses with COVID-19 zoonoses [DOI] 10.3201/eid2609.202059 PMC 바로가기 [Article Type] Research Letter