Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway multiciliated cell differentiation말단 부속기 단백질 CEP164에 대한 조건부 녹아웃 마우스는 기도 다중섬모 세포 분화에서 필수적인 역할을 밝힙니다Research Article Published on 2017-12-152022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence addition affecting airway airways arising Arl13b Asthma basal body binding Brain Cby1 Cell cell differentiation cells CEP164 cerebrospinal fluid characterized chronic obstructive ciliary ciliary dyskinesia circulation clearance component Control COPD Critical cystic fibrosis develop differentiation disease disorder distal docking dysfunction dyskinesia Evidence female reproductive tract fiber fibrosis fluids Genetic genetic disease GTPase Health human biology hydrocephalus implicated Infection infertility knockout mice lack lining male male infertility membrane vesicle membrane vesicles mice modulate molecular mechanism molecular mechanisms Mucociliary clearance Mucus multicilia oviduct Patient Perturbation physiological primary ciliary dyskinesia primary culture Protein Proteins provide recruitment regulate Regulation respiratory respiratory diseases selective Structure Symptom Testis tissue tracheal Transport unique Vesicle while [DOI] 10.1371/journal.pgen.1007128 PMC 바로가기 [Article Type] Research Article
Neutralization of both IL-1α/IL-1β plays a major role in suppressing combined cigarette smoke/virus-induced pulmonary inflammation in miceArticle Published on 2017-06-012023-06-24 Journal: Pulmonary pharmacology & therapeutics [Category] 신종인플루엔자, [키워드] COPD Exacerbation IL-1 pathway pulmonary inflammation Treatment virus [DOI] 10.1016/j.pupt.2017.03.008
Human primary airway epithelial cells isolated from active smokers have epigenetically impaired antiviral responsesResearch Published on 2016-09-072023-06-07 Journal: Respiratory Research [Category] Fulltext, 신종인플루엔자, [키워드] COPD HBEC Human Influenza Innate immunity interferon lung RIG-I TLR3 [DOI] 10.1186/s12931-016-0428-2 PMC 바로가기 [Article Type] Research
The immunogenicity of the intradermal injection of seasonal trivalent influenza vaccine containing influenza A(H1N1)pdm09 in COPD patients soon after a pandemicResearch Paper Published on 2016-07-062023-06-23 Journal: Human vaccines & immunotherapeutics [Category] 신종인플루엔자, [키워드] acute respiratory illness COPD immunogenicity Influenza A(H1N1)pdm09 influenza vaccine Intradermal [DOI] 10.1080/21645515.2016.1149276 PMC 바로가기 [Article Type] Research Paper
Self-reported influenza vaccination and protective serum antibody titers in a cohort of COPD patientsArticle Published on 2016-06-012023-06-24 Journal: Respiratory medicine [Category] 신종인플루엔자, [키워드] COPD Influenza vaccination [DOI] 10.1016/j.rmed.2016.04.008
Cigarette smoke-promoted acquisition of bacterial pathogens in the upper respiratory tract leads to enhanced inflammation in mice담배 연기가 상기도에서 세균 병원체의 획득을 촉진하여 생쥐에서 염증을 증가시킨다.Research Published on 2015-03-202024-08-04 Journal: Respiratory Research [Category] 폐렴구균 감염증, [키워드] bacterial colonization cigarette smoke COPD Inflammation [DOI] 10.1186/s12931-015-0204-8 PMC 바로가기 [Article Type] Research
Clinical factors associated with the humoral immune response to influenza vaccination in chronic obstructive pulmonary diseaseOriginal Research Published on 2014-12-242023-06-09 Journal: International journal of chronic obstructive pulmo [Category] 신종인플루엔자, [키워드] COPD Human influenza Humoral immunity influenza vaccines vaccination [DOI] 10.2147/COPD.S53590 PMC 바로가기 [Article Type] Original Research
Inflammatory thresholds and the species-specific effects of colonising bacteria in stable chronic obstructive pulmonary disease안정적인 만성 폐쇄성 폐질환에서 염증 역치와 정착 세균의 종 특이적 효과Research Published on 2014-09-142024-08-04 Journal: Respiratory Research [Category] 폐렴구균 감염증, [키워드] Bacteria colonisation COPD Inflammation [DOI] 10.1186/s12931-014-0114-1 PMC 바로가기 [Article Type] Research
IgM levels in plasma predict outcome in severe pandemic influenzaArticle Published on 2013-11-012023-06-25 Journal: Journal of Clinical Virology [Category] 신종인플루엔자, [키워드] CAP chronic obstructive pulmonary disease community acquired pneumonia COPD Critical Cytokines HBP high blood pressure ICU immunoglobulins Influenza intensive care unit Prognosis [DOI] 10.1016/j.jcv.2013.09.006
Efficacy and effectiveness of seasonal and pandemic A (H1N1) 2009 influenza vaccines in low and middle income countries: a systematic review and meta-analysisReview Published on 2013-10-252023-06-24 Journal: Vaccine [Category] 신종인플루엔자, [키워드] chronic obstructive pulmonary disease COPD developing countries Effectiveness Efficacy HIC high income country ILI Influenza influenza-like illness LIC LMIC low and middle income country low income country MIC, middle income country Randomized controlled trial RCT Vaccine [DOI] 10.1016/j.vaccine.2013.08.056 [Article Type] Review