Artificial Intelligence Predicts Severity of COVID-19 Based on Correlation of Exaggerated Monocyte Activation, Excessive Organ Damage and Hyperinflammatory Syndrome: A Prospective Clinical Study인공 지능, 과장된 단핵구 활성화, 과도한 장기 손상 및 과염증 증후군의 상관 관계를 기반으로 COVID-19의 심각도 예측: 전향적 임상 연구Immunology Published on 2021-08-272022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커, 진단, [키워드] Accuracy Admission Alanine alanine aminotransferase Algorithms ALT Analysis analyzed applied artificial artificial intelligence aspartate Aspartate aminotransferase AST biochemical analyses Biomarker C-reactive protein C-reactive protein (CRP chemokine chemokines clinical COVID-19 COVID-19 patient COVID-19 patients creatinine CT scan CT scans cytokine Cytokines D-dimer damage develop eight fibrinogen forest gamma interferon Glucose healthy control HMGB1 hospitalized COVID-19 patient identify IL-6 intelligence interferon Laboratory Lactate lactate dehydrogenase LDH Logistic regression Lungs Macrophage macrophage derived cytokine management mDC methodology MIG moderate moderate disease monocyte monokine objective on admission parameter predict prediction prediction models predictor Prognostic factor Prognostic factors Prognostic value Prospective provide Random forest reduce mortality Result severe disease severely ill patient severely ill patients severity severity of COVID-19 significantly higher support vector machine the disease the patient [DOI] 10.3389/fimmu.2021.715072 PMC 바로가기 [Article Type] Immunology
Feasibility and acceptability of SARS-CoV-2 testing and surveillance in primary school children in England: Prospective, cross-sectional studyResearch Article Published on 2021-08-272022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Antibody testing asked Blood blood sample blood test children Complete COVID-19 pandemic cross-sectional England feasibility flexible Frequency Infection initiated nasal swab National nose swab nose swabs Older parent PHE primary school Prospective Public Health England questionnaire raised recruitment reported Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RT-PCR SARS-CoV-2 testing School Schools selected staff student Surveillance Swab throat swab transmission of SARS-CoV-2 widespread [DOI] 10.1371/journal.pone.0255517 PMC 바로가기 [Article Type] Research Article
A Prospective Study of Specialized Coagulation Parameters in Admitted COVID-19 Patients and Their Correlation With Acute Respiratory Distress Syndrome and OutcomePathology Published on 2021-08-262022-10-31 Journal: Cureus [Category] COVID-19, [키워드] abnormality absence activated addressed Admission Affect age antagonist Anticoagulant Anticoagulants Antithrombin aPTT ARDS ARDS patient association AUC automated benefit category Chrom chronic obstructive Coagulation coagulation abnormalities coagulation parameter coagulation test Coagulopathy Comorbidity complication of COVID-19 Contact COPD COVID patient COVID-19 COVID-19 case COVID-19 patient criteria cut-off Cytokine storm D-dimer D-dimer level dead Diabetes Mellitus diagnosis of COVID-19 dimer discharge distress elevated ELISA females fibrinogen fibrinolytic France Free history hospital hypertension ICU identify in-patient incidence INR International liquid male median age Mortality non-survivor normalized objective outcome outcomes Patient patients performed plasma predict Pregnancy presenting prognostic biomarker Prospective Prospective Study Protein protein C Prothrombin time protocol pulmonary disease recruited respiratory Result routine significantly significantly higher SOFA score STAR study inclusion Symptom syndrome therapy tissue plasminogen activator [DOI] 10.7759/cureus.17463 PMC 바로가기 [Article Type] Pathology
Effectiveness of a Three-Week Inpatient Pulmonary Rehabilitation Program for Patients after COVID-19: A Prospective Observational StudyCOVID-19 이후 환자를 위한 3주 입원환자 폐재활 프로그램의 효과: 전향적 관찰 연구Observational Study Published on 2021-08-262022-09-10 Journal: International Journal of Environmental Research an [Category] MERS, SARS, 임상, 치료기술, [키워드] acute COVID-19 acute phase age analyzed Anxiety asked assigned changed course of recovery COVID-19 COVID-19 patient Depression disease severity Dyspnea effect size effect sizes effective Effectiveness Efficacy evaluated exertional dyspnea fatigue female Health status improvement Improvements initial Inpatient inpatient rehabilitation investigated life Lung function medium Mild observational study Other outcome parameter Patient physical capacity Primary outcome Program Prospective prospective observational study pulmonary pulmonary rehabilitation Quality of life Referral rehabilitation respiratory Respiratory disease secondary Secondary outcomes severity symptomatic Symptoms three group three groups [DOI] 10.3390/ijerph18179001 PMC 바로가기 [Article Type] Observational Study
African and Asian Medicinal Plants as a Repository for Prospective Antiviral Metabolites Against HIV-1 and SARS CoV-2: A Mini ReviewPharmacology Published on 2021-08-252022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] African Against antimalarial Antiviral antiviral activity antiviral agent antiviral drugs Artemisinin Asia Asian Clinical management clinical settings clinical study Compound conducted COVID-19 database drug candidate Drug discovery Efficacy excluded Google Scholar HIV-1 HIV/AIDS immune system in silico in vitro in vivo Infectious diseases medicinal plants MINI natural natural antiviral Novel coronavirus pandemic plant Prospective Research review SARS-CoV-2 scientist searched Toxicity triggered viral infection Web of Science [DOI] 10.3389/fphar.2021.703837 PMC 바로가기 [Article Type] Pharmacology
Efficacy of Remdesivir-Containing Therapy in Hospitalized COVID-19 Patients: A Prospective Clinical ExperienceArticle Published on 2021-08-242022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 30-Day mortality Analysis analyzed approved clinical conducted COVID-19 Cox regression analysis enrolled experience HFNC high-flow oxygen therapy Hospitalization hospitalized patient in vitro in vivo Kaplan–Meier mechanical ventilation Mortality NIV no difference non-invasive ventilation Patient patients hospitalized patients treated patients with COVID-19 patients with SARS-CoV-2 Pneumonia primary endpoint propensity score matching Prospective prospective observational study reduced Remdesivir SARS-CoV-2 secondary endpoint significant increases in statistically study groups survival Therapies therapy treated Treatment with COVID-19 [DOI] 10.3390/jcm10173784 PMC 바로가기 [Article Type] Article
Incidence, Risk Factors and Impact on Clinical Outcomes of Bloodstream Infections in Patients Hospitalised with COVID-19: A Prospective Cohort StudyArticle Published on 2021-08-242022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] 95% CI Affect Analysis Antimicrobial stewardship bacterial super-infections bloodstream infection Bloodstream infections BSI clinical consecutive patient corticosteroid therapy corticosteroid treatment COVID-19 development Epidemiology Factor group Hospital stay hospitalised Impact IMV in-hospital mortality incidence increased risk independent IQR Italy Mortality Observational cohort study Patient Prospective risk risk factor significantly treated was performed with COVID-19 [DOI] 10.3390/antibiotics10091031 PMC 바로가기 [Article Type] Article
Combined Percutaneous Tracheostomy and Endoscopic Gastrostomy Tubes in COVID-19: A Prospective Series of Patient OutcomesOriginal Research Published on 2021-08-232022-10-29 Journal: Journal of Intensive Care Medicine [Category] COVID-19, MERS, SARS, [키워드] addition approach clinically collected Combined COVID-19 COVID-19 patient COVID-19 patients Critically ill decannulated Descriptive statistics discharge discharged Effectiveness Efficacy endpoints evaluate gastrostomy healthcare personnel Healthcare provider hospital ICU intensive care mechanical ventilation median Mortality Patient patients patients with COVID-19 Percutaneous Prospective prospective cohort study question required Respiratory failure risk Sery severe respiratory failure survival the median the timing tracheostomy tracheostomy tube transfer tube undergo virus transmission [DOI] 10.1177/08850666211038875 PMC 바로가기 [Article Type] Original Research
Lessons Learned From COVID-19 Contact Tracing During a Public Health Emergency: A Prospective Implementation StudyPublic Health Published on 2021-08-202022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] 95% CI adjusted relative risk aRR Better carried CDC coefficient Community Complete Connecticut Contact Contact tracing COVID-19 Critical declined Epidemics group health equity ICC implementation Implementation science Implementation study IMPROVE Infectious disease infectious disease outbreak influence information investigator lesson median median time multivariable regression models New Nurses Pandemics positive predictor Prospective Public public health Racial reached repeated reported required tracing [DOI] 10.3389/fpubh.2021.721952 PMC 바로가기 [Article Type] Public Health
The effects of hyperbaric oxygen therapy (HBOT) on coronavirus disease-2019 (COVID-19): a systematic review코로나바이러스 질병-2019(COVID-19)에 대한 고압산소 요법(HBOT)의 효과: 체계적인 검토Review Published on 2021-08-192022-09-11 Journal: European Journal of Medical Research [Category] MERS, SARS, 임상, [키워드] adverse event adverse events article assessment tool Blood oxygen saturation clinical trial clinical trials cornerstone coronavirus country COVID-19 COVID-19 treatment database demonstrated Effect effective Efficacy eligible Evidence fair quality Health hyperbaric oxygen Hyperbaric oxygen therapy Hyperbaric oxygenation knowledge less mechanism MOST NIH oxygen Oxygen therapy Oxygenation patients with COVID-19 Prospective PROSPERO receiving Registered reported Result retrieved review Safe SARS-CoV-2 screening process searched systematic review systematic reviews the patient Treatment was used Web of Science [DOI] 10.1186/s40001-021-00570-2 PMC 바로가기 [Article Type] Review