Intranasal vaccination with γ-irradiated Streptococcus pneumoniae whole-cell vaccine provides serotype-independent protection mediated by B-cells and innate IL-17 responses감마 방사선 처리된 폐렴구균 전체 세포 백신을 이용한 비강 내 백신 접종은 B 세포와 선천적 IL-17 반응에 의해 매개되는 혈청형 독립적인 보호를 제공합니다.journal-article Published on 2016-05-012024-08-23 Journal: Clinical Science [Category] 폐렴구균 감염증, [키워드] protective immunity serotype independent Streptococcus pneumoniae Vaccine [DOI] 10.1042/CS20150699 [Article Type] journal-article
Potential protective immunogenicity of tetanus toxoid, diphtheria toxoid and Cross Reacting Material 197 (CRM197) when used as carrier proteins in glycoconjugates당접합체에서 담체 단백질로 사용되는 경우 파상풍 톡소이드, 디프테리아 톡소이드 및 교차 반응 물질 197(CRM197)의 잠재적인 보호 면역원성journal-article Published on 2016-03-032024-07-30 Journal: Human vaccines & immunotherapeutics [Category] 파상풍, [키워드] carrier proteins Combination vaccines Cross Reacting Material 197 diphtheria toxoid Glycoconjugates protective immunity tetanus toxoid [DOI] 10.1080/21645515.2015.1086048 [Article Type] journal-article
A synthetic consensus anti–spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primatesArticle Published on 2015-09-042022-11-01 Journal: Science Translational Medicine [Category] Coronavirus, [키워드] acute respiratory syndrome antigen-specific neutralizing antibody antiviral therapy approved Arabian Peninsula cause caused cellular immunity characteristic Consensus coronavirus deaths disease DNA vaccine Europe exhibited increase in induce Infection lack Lineage macaque macaques MERS MERS coronavirus MERS spike protein MERS-CoV mice Middle East morbidity Mortality nosocomial pathogen Pneumonia Prevent protective immunity protective response Protein Radiographic respiratory syndrome coronavirus rhesus macaque route of infection SARS-CoV seroconverted syndrome The United States Transmission treat Vaccine viral challenge virus-neutralizing [DOI] 10.1126/scitranslmed.aac7462 PMC 바로가기 [Article Type] Article
Broadly protective immunity against divergent influenza viruses by oral co-administration of Lactococcus lactis expressing nucleoprotein adjuvanted with cholera toxin B subunit in miceResearch Published on 2015-08-052023-06-08 Journal: Microbial Cell Factories [Category] 신종인플루엔자, [키워드] L cross influenza A viruses lactis/pNZ8008 NP adjuvanted with CTB protective immunity [DOI] 10.1186/s12934-015-0287-4 PMC 바로가기 [Article Type] Research
Development of an indirect ELISA, blocking ELISA, fluorescent microsphere immunoassay and fluorescent focus neutralization assay for serologic evaluation of exposure to North American strains of Porcine Epidemic Diarrhea VirusMethodology Article Published on 2015-08-012022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] addition Analysis antibody Asia asked assays biotinylated calculated colostrum Coronaviruses correlation country cross-reactivity demonstrated described develop development diagnostic test Disadvantages ELISA epidemic diarrhea expressed fluorescent Fluorescent Focus Neutralization (FFN) Fluorescent microsphere immunoassay (FMIA) functional gastroenteritis highlight IFA Immune status immunoassay immunohistochemistry Interpretation kappa value Laboratory mAb mAbs magnetic bead measurement microsphere MONITOR monoclonal monoclonal antibody multiple antigen naïve Neutralization assay Neutralizing antibodies neutralizing antibody Neutralizing antibody response North North America outbreak pathogen PEDV porcine epidemic diarrhea virus (PEDV) protective immunity quantitation question receiver operating characteristic recent Respiratory Coronavirus Result ROC ROC analysis Sensitivity and specificity Seroconversion Serological assay serology serum serum sample significant level Spread staining strain TGEV vaccine candidate virus virus neutralizing antibodies was performed were used [DOI] 10.1186/s12917-015-0500-z PMC 바로가기 [Article Type] Methodology Article
Evaluation of porcine epidemic diarrhea virus transmission and the immune response in growing pigsResearch Article Published on 2015-05-062022-10-28 Journal: Veterinary Research [Category] Coronavirus, MERS, [키워드] antibody clinical Contact Day demonstrated disease effective Endemic epidemic diarrhea evaluate homologous immune response Infection Infectious virus information initial naïve PCR PCR-negative PCR-positive PEDV pig positive Primary infection protective immunity Re-infection repeated RNA S1 and S2 selected seroconverted Transmission Vaccine virus virus transmission was determined [DOI] 10.1186/s13567-015-0180-5 PMC 바로가기 [Article Type] Research Article
Protective immunity against influenza H5N1 virus challenge in chickens by oral administration of recombinant Lactococcus lactis expressing neuraminidaseResearch Article Published on 2015-04-022023-05-24 Journal: BMC veterinary research [Category] Fulltext, 조류인플루엔자, [키워드] L.lactis/pNZ2103-NA H5N1 virus protective immunity [DOI] 10.1186/s12917-015-0399-4 PMC 바로가기 [Article Type] Research Article
Oral administration of a Spirulina extract enriched for Braun-type lipoproteins protects mice against influenza A (H1N1) virus infectionArticle Published on 2015-02-152023-06-25 Journal: Phytomedicine : international journal of phytother [Category] 신종인플루엔자, [키워드] Arthrospira platensis (Phormidiaceae) Braun-type lipoproteins Immulina(®) influenza A (H1N1) virus protective immunity Toll-like receptor [DOI] 10.1016/j.phymed.2014.12.006
Compound 48/80 acts as a potent mucosal adjuvant for vaccination against Streptococcus pneumoniae infection in young mice화합물 48/80은 어린 생쥐에서 폐렴구균 감염에 대한 백신 접종을 위한 강력한 점막 보조제 역할을 한다.journal-article Published on 2015-02-012024-08-04 Journal: Vaccine [Category] 폐렴구균 감염증, [키워드] mucosal adjuvant nasal colonization protective immunity Streptococcus pneumoniae [DOI] 10.1016/j.vaccine.2015.01.013 [Article Type] journal-article
Maximal immune response and cross protection by influenza virus nucleoprotein derived from E. coli using an optimized formulationArticle Published on 2014-11-012023-06-24 Journal: Virology [Category] 신종인플루엔자, [키워드] Al(OH)(3) CpG influenza A virus nucleoprotein protective immunity Protein subunit vaccines. [DOI] 10.1016/j.virol.2014.08.008