single-center – Page 33 – Communicable Diseases Research

Severe COVID-19 in the intensive care unit: a case series

Case Reports

Published on 2021-05-032022-10-04
Journal: Journal of Medical Case Reports [Category] 임상,

Clinical characteristics and outcomes of hospitalized COVID-19 patients in a MERS-CoV referral hospital during the peak of the pandemic

대유행이 정점에 달했을 때 MERS-CoV 위탁 병원에 입원한 COVID-19 환자의 임상적 특성 및 결과

Article

Published on 2021-05-012022-09-11
Journal: International Journal of Infectious Diseases [Category] 치료기술,

[키워드] 95%CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission age AST biochemical marker Care case sery Characteristics city clinical Clinical characteristics Co-infection Comorbidity coronavirus coronavirus disease Coronavirus disease 2019 cough COVID-19 creatinine CRP D-dimer death diabete diabetes Dyspnea elevated end-organ damage Fever hospital Hospitalized hospitalized COVID-19 patient hypertension ICU IL-6 individual Infection intensive care intensive care unit King KSUMC less lymphocyte Lymphocyte count lymphopenia male median age MERS MERS-CoV Middle East respiratory syndrome Middle East respiratory syndrome Coronavirus Mortality Most patient Most patients Older Older age outcome pandemic Patient patients required hospitalization polymerase positive real time respiratory syndrome coronavirus reverse transcriptase risk factor Risk factors RT-PCR SARS-CoV-2 Saudi Arabia Seven severe acute respiratory syndrome Coronavirus Severe case severe cases significant increase single-center Symptom symptom duration tested transcriptase troponin Troponin-I university ventilatory support
[DOI] 10.1016/j.ijid.2021.03.058 PMC 바로가기 [Article Type] Article

Effect and safety of Chinese herbal medicine granules in patients with severe coronavirus disease 2019 in Wuhan, China: a retrospective, single-center study with propensity score matching

2019년 중국 우한에서 발생한 중증 코로나바이러스 질환 환자에서 한약 과립의 효과 및 안전성: 성향 점수 매칭을 통한 후향적 단일 센터 연구

Article

Published on 2021-05-012022-08-31
Journal: Phytomedicine : international journal of phytother [Category] 치료제,

[키워드] 1:1 28-day mortality baseline category caused Chinese Chinese herbal medicine CHM Clinical improvement Computerized tomography coronavirus disease Coronavirus disease 2019 cough COVID-19 D-dimer level Day defined duration of fever Dyspnea Effect Fever fibrinolysis Granule granules Health herbal medicine high risk hospital lung lung lesion male no significant difference Ordinal Scale Patient patients treated Primary outcome propensity score matching PSM reduced retrospective Retrospective study severe coronavirus disease severe COVID-19 significant difference single-center single-center study the patient Treatment treatment effect usual care usual care alone was used Wuhan
[DOI] 10.1016/j.phymed.2020.153404 PMC 바로가기 [Article Type] Article

Identification of Distinct Immunophenotypes in Critically Ill Coronavirus Disease 2019 Patients

중환자 코로나바이러스 질환 2019 환자에서 뚜렷한 면역표현형 식별

Article

Published on 2021-05-012022-08-31
Journal: Chest [Category] MERS, SARS, 바이오마커,

[키워드] Activation Acute respiratory failure cause CD4+ CD8+ clinical trial Cluster Clustering complement Complement activation conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critical Critical care Critically ill critically ill COVID-19 patients cytokine cytokine level cytokine release elevated eligibility endothelial enrolled evaluated exaggerated inflammatory response exhibiting favor feature France group heterogeneous Hierarchical hierarchical clustering Hypogammaglobulinemia ICU ICU admission identification IL-1β IL-6 IL-8 Ill immunodeficiency immunologically immunology immunophenotype Infection Inflammation inflammatory reaction lung damage marker mediators moderate multi-organ dysfunction Necrosis outcomes Patient patient identification patients phenotype predominant principal components principal components analysis Profiling Prospective Study respiratory Respiratory failure response to therapies SARS-CoV-2 SARS-COV-2 infection SC5b-9 Severe acute respiratory syndrome severe acute respiratory syndrome-coronavirus-2 severe COVID-19 severity shown single-center targeted therapy therapeutic therapy Trajectories tumor necrosis tumor necrosis factor tumor necrosis factor-alpha Variability variable
[DOI] 10.1016/j.chest.2020.11.049 PMC 바로가기 [Article Type] Article

Coronavirus Disease 2019 in Kidney Transplant Recipients: Single-Center Experience and Case-Control Study

신장 이식 수혜자의 코로나바이러스 질병 2019: 단일 센터 경험 및 사례 통제 연구

Article

Published on 2021-05-012022-09-11
Journal: Transplantation proceedings [Category] SARS, 치료제,

[키워드] age and sex Bacterial infections calcineurin Case fatality rate Case series Clinical course Clinical outcome clinical outcomes comparable Control controls coronavirus disease Coronavirus disease 2019 COVID-19 diagnosed with COVID-19 died drug level exclusion experience fatality Hemodialysis Hospitalized Immunosuppression Infection inhibitor kidney transplant recipients mammalian morbidity morbidity and mortality mTOR no significant difference no significant differences non-transplant patient non-transplant patients outcome pandemic Rapamycin recipient Secondary infection secondary infections single-center Sirolimus tacrolimus Transplant with COVID-19
[DOI] 10.1016/j.transproceed.2021.01.002 PMC 바로가기 [Article Type] Article

Use of conventional synthetic and biologic disease-modifying anti-rheumatic drugs in patients with rheumatic diseases contracting COVID-19: a single-center experience

Case Reports

Published on 2021-05-012022-10-05
Journal: Rheumatology International [Category] SARS, 임상,

[키워드] adjusted affected ankylosing spondylitis Arthritis Autoimmune rheumatic disease biologic changed clinical manifestation clinical response Comorbidity COVID-19 COVID-19 disease course disease course disease-modifying anti-rheumatic drug drug Drug side effect expressed Follow-up General population hospital Inflammatory arthritis investigated Laboratory mild COVID-19 symptoms olfactory dysfunction outcome Patient Pneumonia prospective observational study psoriatic arthritis receiving recorded respiratory symptom rheumatic disease Rheumatoid rheumatoid arthritis SARS-COV-2 infection single-center sore throat spondylitis systemic manifestation treated Treatment
[DOI] 10.1007/s00296-021-04818-2 PMC 바로가기 [Article Type] Case Reports

Diagnostic Delay of Pulmonary Embolism in COVID-19 Patients

Medicine

Published on 2021-04-302022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

Statistical analysis plan for the Surgery for Cancer with Option of Palliative Care Expert (SCOPE) trial: a randomized controlled trial of a specialist palliative care intervention for patients undergoing surgery for cancer

Randomized Controlled Trial

Published on 2021-04-292022-10-04
Journal: Trials [Category] MERS, SARS, 임상,

Severe COVID-19 Associated With Liver Injury in Patients Without Preexisting Liver Disease

Family/General Practice

Published on 2021-04-262022-10-31
Journal: Cureus [Category] COVID-19,

Safety and immunogenicity of the SARS-CoV-2 BNT162b1 mRNA vaccine in younger and older Chinese adults: a randomized, placebo-controlled, double-blind phase 1 study

Research

Published on 2021-04-222022-10-05
Journal: Nature Medicine [Category] SARS, 임상, 진단,

[키워드] acute respiratory syndrome Adults adverse event Asian BNT162b1 China Chinese clinical investigation convalescent coronavirus COVID-19 domain dose double-blind effective ENCODE event geometric healthy human sera humoral immunogenicity data interferon-γ Jiangsu local reaction Mild moderate mRNA vaccine Neutralizing titer Older pandemic parallel-group participant Participants peptide pool phase 1 study phase 1 trial Placebo placebo-controlled polymerase chain positive prime and boost Randomized RBD reached receive response robust Safety safety profile SARS-CoV-2 single-center spike glycoprotein the RBD the SARS-CoV-2 the vaccine Tolerability treatment group vaccination Vaccine vaccine candidate
[DOI] 10.1038/s41591-021-01330-9 [Article Type] Research