Saliva specimens for detection of severe acute respiratory syndrome coronavirus 2 in Kuwait: A cross-sectional studyArticle Published on 2020-10-012022-10-04 Journal: Journal of Clinical Virology [Category] SARS, 진단, 치료기술, [키워드] 95 % CI acute respiratory syndrome affecting agreement Analysis analyzed can be used caused claimed collected confirmed case coronavirus Coronavirus disease 2019 COVID-19 cross-sectional demonstrated detection rate diagnosis of COVID-19 diagnostic diagnostic test global pandemic Infection investigated Kuwait multiplex Nasopharyngeal swab noninvasive NPs Patient patients PCR PCR test positive real-time reverse transcriptase RT-PCR Saliva saliva specimen saliva specimens SARS-CoV-2 screened Sensitivity and specificity specimen suspected patient [DOI] 10.1016/j.jcv.2020.104652 PMC 바로가기 [Article Type] Article
Comparison of the diagnostic efficacy between two PCR test kits for SARS‐CoV‐2 nucleic acid detectionResearch Article Published on 2020-09-252022-10-30 Journal: Journal of Clinical Laboratory Analysis [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome analyzed Biotechnology China clinically collected coronavirus coronavirus disease COVID‐19 diagnosed diagnostic diagnostic efficacy Efficacy hospitalized patient N gene Negative predictive value NPV nucleic acid Nucleic acid detection ORF1ab PCR PCR kit PCR test performed polymerase chain positive Positive predictive value PPV Result reverse transcription RT‐PCR RT‐PCR test SARS‐CoV‐2 SARS‐CoV‐2 sensitivity Shanghai specificity swab sample Throat throat swab Variation [DOI] 10.1002/jcla.23554 PMC 바로가기 [Article Type] Research Article
A quadruple blind, randomised controlled trial of gargling agents in reducing intraoral viral load among hospitalised COVID-19 patients: A structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-09-142022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] administration age antiviral therapy approved asked assumption blind blinded carried Chemical Chemotherapy clinical clinical trial COVID COVID-19 COVID-19 patient COVID-19 positive patients Cytokine analysis cytokine profile determine dissemination edentulous Effectiveness element eligibility assessment excluded expected explained female FIVE Flow gargles Glasgow coma score group hospitalised hydrogen hypertonic identify IFN-γ IL-10 IL-2 IL-4 IL-6 Immunological test Inc. inclusion criteria Intervention Intubated Karachi Laboratory laboratory-confirmed lesion male Mild moderate disease mucosal nasal Nasal lavage number objective outcome parallel group participant Patient PCR test positive controls Primary outcome product protocol provided Purposive sampling quantitative PCR Radiotherapy randomised randomised controlled trial real time reducing reduction in Registered reported Research Research question salivary Sample size sealed Standard status study group Study protocol subject Symptoms the patient TNF-α treated Trial unit university university hospital Viral load website [DOI] 10.1186/s13063-020-04634-2 PMC 바로가기 [Article Type] Letter
Testing for COVID-19 at travel clinics in JapanArticle Published on 2020-08-202023-06-20 Journal: Journal of Travel Medicine [Category] Fulltext, MERS, [키워드] Nasopharyngeal swab PCR test SARS-CoV-2 Travel certificate travel limitations travel requirements Travel restrictions [DOI] 10.1093/jtm/taaa107 PMC 바로가기
Serological differentiation between COVID-19 and SARS infectionsCOVID-19와 SARS 감염의 혈청학적 구별Research Article Published on 2020-07-072022-08-13 Journal: Emerging Microbes & Infections [Category] MERS, SARS, 임상, [키워드] acute disease anti-N antibodies Anti-RBD antibodies antibody antibody tests asymptomatic infection rate asymptomatic infection rates best Betacoronavirus Blood capture caused choice Contact tracing Coronaviridae coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 antibody test COVID-19 antibody tests cross-reactivity diagnostic diagnostic test diagnostic tests Disease diagnosis ELISA family Coronaviridae genus genus Betacoronavirus herd immunity humans Immunity infect Infection N protein offer other coronavirus outbreak PCR PCR test PCR tests performed protective immunity Protein RBD region required SARS SARS infection SARS patient SARS-CoV SARS-CoV-2 sequence identity sera serological test Serological tests serology significant level species specificity survivor virus waned while [DOI] 10.1080/22221751.2020.1780951 PMC 바로가기 [Article Type] Research Article
Redesigning Portable Health Clinic Platform as a Remote Healthcare System to Tackle COVID-19 Pandemic Situation in Unreached CommunitiesArticle Published on 2020-06-302022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] affected Algorithm boost chronic cardiovascular clinic Community contribute COVID-19 developing countries digestive disease Endocrine healthcare healthcare worker help individual initial knowledge Measures medical services Nurses pandemic patients PCR test platform Population portable health clinic Public health response remote remote healthcare system renal Research risk risk of infection SARS-CoV-2 transmission Science Self-efficacy situation spread of COVID-19 symptoms of COVID-19 System the patient the WHO unreached communities [DOI] 10.3390/ijerph17134709 PMC 바로가기 [Article Type] Article
Global Comparison of Changes in the Number of Test-Positive Cases and Deaths by Coronavirus Infection (COVID-19) in the WorldArticle Published on 2020-06-182022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] affected Analysis analyzed Asia BPI cause change changes in coronavirus country COVID-19 death distribution Factor Genetic highest include increase in Infection infection management Infectious disease kinetic analysis Latin America less machine Middle East Mortality National number PCR test positive rate positive rates proportion Region Spread subsequent suggested trajectory [DOI] 10.3390/jcm9061904 PMC 바로가기 [Article Type] Article
Clinical Factors, Preventive Behaviours and Temporal Outcomes Associated with COVID-19 Infection in Health Professionals at a Spanish HospitalArticle Published on 2020-06-162022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] affected analysed analyses Analysis clinical conducted Contagion cough COVID COVID-19 determine estimate Face mask Factor fatigue Fever first positive Follow-up Gastrointestinal symptom healthcare healthcare professionals indicate Infection men negativization novel coronavirus disease Older outbreak outcome pandemic patients PCR PCR test PCR testing Prevalence preventive measure professional professionals reported required risk SARS-CoV-2 Spain Spanish Spread survival Symptoms Temporal the median These data variables with COVID-19 women [DOI] 10.3390/ijerph17124305 PMC 바로가기 [Article Type] Article
Evaluating the efficacy and safety of human anti-SARS-CoV-2 convalescent plasma in severely ill adults with COVID-19: A structured summary of a study protocol for a randomized controlled trialLetter Published on 2020-06-082022-10-29 Journal: Trials [Category] COVID-19, SARS, [키워드] activity adverse event allergic reaction anti-SARS-CoV-2 anti-SARS-CoV-2 antibody Anti-SARS-CoV-2 plasma Anti-viral blinded Blood blood product center Chest radiography Clinical improvement Clinical outcome clinical status clinical trial clinician collected Columbia University control arm convalescent plasma coronavirus COVID-19 COVID-19 symptom criteria cumulative Date defined Dilution discharge dissemination Donor ECMO Efficacy Efficacy and safety element evaluate Evaluating Evidence extracorporeal membrane oxygenation hazard hazard ratio HBV HCV HIV hospital Hospitalized hospitalized patient IgA deficiency immune incidence include Infection Influenza Invasive mechanical ventilation mechanical ventilation multi-organ failure nasopharyngeal Nasopharyngeal swab New York Non-invasive number objective occur oropharyngeal swab outcome oxygen saturation participant Participants patients hospitalized PCR test PCR-negative per-protocol analysis peripheral capillary plasma platform post-hoc analysis Pregnancy primary endpoint protocol randomization Randomized Randomized controlled trial randomized, controlled trial randomly permuted block receive Registered Remdesivir requiring high-flow oxygen requiring supplemental oxygen Research Respiratory failure retrospective Ritonavir safety endpoint Sample size SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection screened Serious Adverse Event seven-point ordinal scale severe COVID-19 severe SARS-CoV-2 severely ill adult single-center spike trimer SpO2 status study participant study period Study protocol supplemental oxygen tested therapy transfused Treatment treatment for COVID-19 Trial undergo USA Version Volunteer Wald test website with COVID-19 World Health Organization ZIKV [DOI] 10.1186/s13063-020-04422-y PMC 바로가기 [Article Type] Letter
Treatment with Hydroxychloroquine vs Hydroxychloroquine + Nitazoxanide in COVID-19 patients with risk factors for poor prognosis: A structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-06-082022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] 1:1 6 hour activity Analysis Antiviral effect blinded Chloroquine Complication contraindication Control control group COVID-19 COVID-19 patient COVID-19 PCR test COVID-19 positive patient Date death determine Diabetes Mellitus dissemination dose Dual therapy Efficacy element Elimination expected Follow-up greater Hospital admission hospital discharge Hydroxychloroquine hypertension inherent Intervention Intubated invasive mechanical management Mechanical mechanical ventilation medication MERS monotherapy nitazoxanide number obesity objective Older outcome parallel group participant Patient patients with COVID-19 PCR test percentage Placebo positive patients Presence protocol QT interval QTc randomised randomised controlled trial Randomized Randomly reached receive recruited recruitment reducing required risk factor Sample size SARS-CoV-2 sealed Seven state status Study protocol therapy Toluca treat treated Treatment treatment regimen Trial Ventilation ventilatory support virus website [DOI] 10.1186/s13063-020-04448-2 PMC 바로가기 [Article Type] Letter