severe cases – Page 34 – Communicable Diseases Research

Within-Host Diversity of SARS-CoV-2 in COVID-19 Patients With Variable Disease Severities

Cellular and Infection Microbiology

Published on 2020-10-062022-10-31
Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS,

Association between ABO blood groups and COVID-19 infection, severity and demise: A systematic review and meta-analysis

Research article

Published on 2020-10-012022-10-05
Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 유전자 메커니즘,

Gut Microbiota Dysbiosis–Immune Hyperresponse–Inflammation Triad in Coronavirus Disease 2019 (COVID-19): Impact of Pharmacological and Nutraceutical Approaches

Review

Published on 2020-10-012022-10-29
Journal: Microorganisms [Category] COVID-19,

Mesenchymal Stem Cells and Their Extracellular Vesicles: A Potential Game Changer for the COVID-19 Crisis

Cell and Developmental Biology

Published on 2020-09-302022-10-31
Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19,

[키워드] “cytokine storm” acute respiratory distress ARDS Corona virus COVID-19 COVID-19 patient COVID-19 patients crisis Cytokine storm death dependent on disease Effects ENhance Exosomes Extracellular vesicles game global public health help immune response immune system immunomodulation immunomodulatory effect immunomodulatory property IMPROVE induce infected patients Inflammatory response intervene kill lack mechanism Mesenchymal stem cells MSC MSCs Multi-organ damage organ outbreak outcome Patient Potential preventive measure PROTECT provide regulate responsible resulting SARS-CoV-2 severe cases severity of COVID-19 STEM stem cell syndrome the disease therapeutic tissue-repair Treatment turn virus
[DOI] 10.3389/fcell.2020.587866 PMC 바로가기 [Article Type] Cell and Developmental Biology

The prediction for development of COVID-19 in global major epidemic areas through empirical trends in China by utilizing state transition matrix model

Research Article

Published on 2020-09-292022-10-28
Journal: BMC Infectious Diseases [Category] COVID-19, SARS,

Immune dysfunction following COVID-19, especially in severe patients

Article

Published on 2020-09-282022-10-04
Journal: Scientific Reports [Category] SARS, 치료제,

[키워드] Analysis B cell blood cell count CD4 CD8 cell count characteristic clinical feature coagulation function collected Complete coronavirus disease COVID-19 COVID-19 patient Critical CT scan D-dimer Disease progression disease severity Diseases dysfunction dysregulated immune response healthy identify immunology include Inflammatory cytokines Logistic regression analysis lymphocyte Medical research Microbiology mild patients multivariate neutrophil count Neutrophil-to-lymphocyte ratio NK cell NLR outcomes parameter participant patients Predictive progressed progression Pulmonary infection recruited risk factor Risk factors ROC SARS-CoV-2-infected patient severe cases severe group Severe patient shown Surveillance T cell T lymphocyte White blood cell
[DOI] 10.1038/s41598-020-72718-9 PMC 바로가기 [Article Type] Article

The Relationship of COVID-19 Severity with Cardiovascular Disease and Its Traditional Risk Factors: A Systematic Review and Meta-Analysis

Original Research

Published on 2020-09-222022-10-31
Journal: Global Heart [Category] COVID-19,

[키워드] acute respiratory distress adjusted Admission age age and sex analyses cardiovascular cardiovascular disease conducted COVID-19 COVID-19 patient CVD death defined diabete diabetes eight eligible English estimate Factor Factors hypertension inclusion criteria independent inhibitor intensive care Male sex mechanical ventilation Meta-analysis Meta-regression analyses meta-regression analysis multivariable analysis performed predict Random-effects models relationship renin-angiotensin system reported review risk risk factor Risk factors searched severe cases severe coronavirus disease severe COVID-19 suggested syndrome systematic review Traditional
[DOI] 10.5334/gh.814 PMC 바로가기 [Article Type] Original Research

The Prognostic Value of Thrombocytopenia in COVID-19 Patients; a Systematic Review and Meta-Analysis

Review Article

Published on 2020-09-192022-10-27
Journal: Archives of Academic Emergency Medicine [Category] COVID-19,

Effects of Antimalarial Drugs on Neuroinflammation-Potential Use for Treatment of COVID-19-Related Neurologic Complications

Article

Published on 2020-09-082022-10-30
Journal: Molecular neurobiology [Category] COVID-19, MERS, SARS,

[키워드] activated addition Affect affecting Aminoacridine anti-inflammatory agents Anti-inflammatory drugs antimalarial Antimalarials Aortic body arachidonic acid blood vessels Brain endothelial cells carotid body Cell culture Central nervous system Chloroquine clinical trial CNS combating Complication coronavirus coronavirus disease Coronavirus replication COVID COVID-19 COX cPLA₂ cross cytokine Cytokine storm cytosolic Cytosolic phospholipase A₂ Dementia disorder DMT1 drug Effect Eicosanoids ENhance expression free radical Free radical damage free radical formation generate Glossopharyngeal nerve hippocampus Hydroxychloroquine Hypoxemia impair induce Inflammation Inflammatory response inhibit inhibiting inhibition inhibitor iron accumulation Iron transport isoform isoforms lung lysosomal enzymes lysosome Lysosomes mice Microcirculation microglia Microvessels Neuroinflammation Neurovascular Nucleus of the tractus solitarius organ oxidative damage oxidative stress PLA2G2D pro-inflammatory produced quinacrine reducing Respiratory centre resulting SARS SARS-CoV SARS-CoV-2 SARS-CoV-2 virus Secretory phospholipase A₂ Seizures severe cases shown silent sPLA₂ IID statins stroke the SARS-CoV-2 virus tissue TNF-α Treatment unique vagus nerve Vascular vascular dementia viral replication
[DOI] 10.1007/s12035-020-02093-z PMC 바로가기 [Article Type] Article

Low high-density lipoprotein level is correlated with the severity of COVID-19 patients: an observational study

낮은 고밀도 지단백 수치는 COVID-19 환자의 중증도와 상관관계가 있습니다: 관찰 연구

Research

Published on 2020-09-072022-08-13
Journal: Lipids in Health and Disease [Category] Biochemistry, COVID-19, SARS,

[키워드] 95% CI Admission adopted age age and gender blood lipid blood lipid level blood lipid levels C-reactive protein C-reactive protein (CRP China cholesterol Clinical data coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 COVID-19 adult patients COVID-19 patient COVID-19 patients Cox regression analysis diagnosed elevated enrolled event events Gender HDL-C healthy high-density High-density lipoprotein High-density lipoprotein cholesterol higher risk infected with COVID-19 interquartile range Kaplan-Meier LDL-C lipoprotein cholesterol Lipoproteins Low-density lipoprotein Low-Density Lipoprotein cholesterol male Mann-Whitney test median non-severe patients participant Patient Prognosis proportion RANK Result Retrospective analysis Severe case severe cases severe COVID-19 patient severe COVID-19 patients severity of COVID-19 significantly lower Total cholesterol Triglyceride underlying diseases were used
[DOI] 10.1186/s12944-020-01382-9 PMC 바로가기 [Article Type] Research