Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
Article
[키워드] administration
Antiviral
antiviral therapy
bat-CoV
bat-CoVs
Cell culture
circulating
clinical development
Clinical sign
CoV
CoV infection
CoVs
disease
Ebola virus disease
effective
Endemic
Epidemic
epithelial
Evidence
functions
globe
GS-5734
heterogeneous
Host
hosts
Human
human CoV
human lung cells
human population
immunologically
in vitro
infections
inhibit
inhibiting
lung viral load
medical need
MERS-CoV
Middle East
naïve
nucleotide prodrug
Pathogenesis
primary human airway
Prophylactic
reduced
Replication
Respiratory disease
SARS-CoV
severe disease
significantly
Spread
therapeutic
therapy
Treatment
Vaccines
viral infection
zoonotic
Zoonotic coronavirus
[DOI] 10.1126/scitranslmed.aal3653 PMC 바로가기 [Article Type] Article
[DOI] 10.1126/scitranslmed.aal3653 PMC 바로가기 [Article Type] Article