COVID-19 in Amazonas, Brazil, was driven by the persistence of endemic lineages and P.1 emergence Research Published on 2021-05-012022-10-05 Journal: Nature Medicine [Category] SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome affected B.1.1.28 Brazil clade Combination complex COVID-19 COVID-19 epidemic dissemination driven by Endemic Epidemiology exponential growth phase Genome genomic Lineage Local mechanism P.1 parental persistence Region replaced risk SARS-CoV-2 second wave Social distancing measure Support variant virus VoC [DOI] 10.1038/s41591-021-01378-7 [Article Type] Research
Assessment and management of asymptomatic COVID-19 infection: A systematic review무증상 COVID-19 감염 평가 및 관리: 체계적인 검토Article Published on 2021-05-012022-09-11 Journal: Travel medicine and infectious disease [Category] SARS, 치료제, [키워드] age assessment Asymptomatic Asymptomatic COVID-19 asymptomatic individual Asymptomatic individuals asymptomatic infection Azithromycin calculate can not case sery Cohort COVID-19 cross-sectional Cross-sectional studies database diagnosis of COVID-19 discharge discharged dissemination FIVE Hospitalization Hydroxychloroquine individual individuals interferon Lopinavir Lopinavir/ritonavir male management Negative PCR nine Patient patients Prevalence proportion random-effects model remained Retrospective study ribavirin Ritonavir SARS-CoV-2 searched shown standard treatment symptomatic systematic review Treatment was used [DOI] 10.1016/j.tmaid.2021.102058 PMC 바로가기 [Article Type] Article
Next-Generation Scholarship: Rebranding Hematopathology Using Twitter: The MD Anderson Experience차세대 장학금: Twitter를 사용한 혈액 병리학 브랜드 변경: MD Anderson 경험Editorial Published on 2021-05-012022-09-11 Journal: Modern pathology : an official journal of the Unit [Category] 진단, 치료기술, [키워드] activity amplify Anderson approach boost Community COVID-19 pandemic disease dissemination editorial expand experience facilitate genomic increasingly instantaneous Interaction knowledge medium molecular Patient care platform Precision promote social media social media platforms [DOI] 10.1038/s41379-020-00715-4 PMC 바로가기 [Article Type] Editorial
Characterization and Comparison of the Utilization of Facebook Groups Between Public Medical Professionals and Technical Communities to Facilitate Idea Sharing and Crowdsourcing During the COVID-19 Pandemic: Cross-sectional Observational StudyOriginal Paper Published on 2021-04-302022-10-30 Journal: JMIR Formative Research [Category] COVID-19, [키워드] Algorithm Characteristics characterization characterized cognitive intelligence communication COVID-19 COVID-19 pandemic Crowdsourcing dissemination Evidence-based Facebook Facebook groups facilitate greater greatest number group groups highest highlight idea information Internet layperson less mechanism media Medical crisis Multiple no significant difference objective professional professionals Public reaction resource Result significantly significantly more Social distancing measure social media Stata Stata Corp statistical analysis utilization virtual communities was selected was used were recorded [DOI] 10.2196/22983 PMC 바로가기 [Article Type] Original Paper
The impact of theory-based messages on COVID-19 vaccination intentions: a structured summary of a study protocol for a randomised controlled trial이론 기반 메시지가 COVID-19 백신 접종 의도에 미치는 영향: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-04-292022-09-10 Journal: Trials [Category] MERS, 임상, [키워드] 1:1 allocation approach automatically blinded Blinding comparator Contact contact with COVID-19 COVID-19 illness COVID-19 vaccination COVID-19 vaccine creating dissemination element ethnic group exposure to Follow-up Gender hypothesised illness beliefs Image individual individually randomised information initiate Intention Intervention investigator investigators messaging minute Necessity-Concerns Framework number objective online survey software outcome oversampling pandemic participant Participants performed post-intervention proportion Prospective protocol randomised randomised controlled trial receive reported Sample size secondary Secondary outcomes Side effect Side effects status Study protocol supplementary material treatment beliefs Trial Trial registration two group two groups Two-arm uptake vaccination vaccination against COVID-19 vaccination intention Vaccine vaccine for COVID-19 Vaccine hesitancy variable website [DOI] 10.1186/s13063-021-05277-7 PMC 바로가기 [Article Type] Letter
The Impact of Health Information Exposure and Source Credibility on COVID-19 Vaccination Intention in GermanyArticle Published on 2021-04-282022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] addition Adults age contribute coronavirus disease COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines credibility diminishe dissemination effective exposure exposure to health information sources Germany health authorities health information health information sources healthcare Impact information Intention Local media medical countermeasure Multiple linear regression outbreak positive reduction Research Result Source source credibility statistical analysis transmission rate vaccination vaccination intention Vaccine hesitancy [DOI] 10.3390/ijerph18094678 PMC 바로가기 [Article Type] Article
Natural tannin extracts supplementation for COVID-19 patients (TanCOVID): a structured summary of a study protocol for a randomized controlled trialCOVID-19 환자를 위한 천연 탄닌 추출물 보충제(TanCOVID): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-04-282022-09-10 Journal: Trials [Category] MERS, SARS, 임상, [키워드] 1:1 24 hour 24 hours addition Administered administration affected age All trial participants all-cause mortality Alpha alpha error Antibiotic therapy antipyretics assigned assisted ventilation Azithromycin B12 blinded Blinding branch Buenos Aire Buenos Aires can not Chestnut tannins Clinical symptoms clinical trial closure cognitive computer-generated random numbering conditions Consent control group COVID-19 COVID-19 patient criteria cytokine Cytokines Day Decline decrease defined Definition Department described diagnosis of SARS-CoV-2 dietary supplement difference disease dissemination dose double-blind Efficacy element eligibility eligible enrolled Enrollment enrolment epidemiological evaluate excluded fecal Final first dose first visit Gender gut microbiota Hospital de Clínica Hospital de Clínicas Hospital de Clinicas Jose de San Martin hospital discharge Hydroxychloroquine hypersensitivity ICU impaired consciousness increase in indicated Infection Infectious disease Infectious diseases Inflammation inflammatory mediator Inflammatory mediators Informed consent intestinal intestinal permeability invasive ventilation lactating Level Lopinavir mean difference measure mechanical ventilation mediators microbiota modifications molecular natural non-invasive ventilation number objective Older outcome parallel-group parameter participant Participation Patient patients per day Placebo placebo-controlled platform Potential power power of 80% protocol Quebracho tannins randomization Randomized Randomized controlled trial Randomly Real-time PCR receive recruited recruitment Registered Research Ritonavir Sample size SARS-COV-2 infection SARS-CoV2 screened secondary secondary outcome measures severity Standard therapy standard treatment status study participant Study protocol study randomization submitted supplementary material supply tannin tannins therapy time Time frame took place Treatment treatment allocation Trial trial participant Trial registration undergo university Ventilation website [DOI] 10.1186/s13063-021-05281-x PMC 바로가기 [Article Type] Letter
Efficacy and safety of nelfinavir in asymptomatic and mild COVID-19 patients: a structured summary of a study protocol for a multicenter, randomized controlled trial무증상 및 경증 COVID-19 환자에 대한 nelfinavir의 효능 및 안전성: 다기관, 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-04-282022-09-10 Journal: Trials [Category] SARS, 임상, 치료기술, [키워드] 1:1 Administered administration adverse event adverse events age all-cause mortality ALT Analysis anticipated Antigen antiviral efficacy AST Asymptomatic asymptomatic patients blinded blinded outcome assessment Blinding blood glucose body temperature both group both groups capture caused childbearing potential clearance clinical Clinical efficacy clinical examinations Clinical symptoms clinical trial clinical trials comparator Patients condition Consent contraceptive method Controlled clinical trial cough COVID-19 creatinine creatinine clearance dataset Day defervescence diabete diabetes diarrhea discretion dissemination distribution drug element enrolled enrolment evaluate event exclusion criteria exploratory Factor female patient Fever Frequency Glucose group hazard ratio Hemophiliac Hemorrhagic history HIV infection hospital hypersensitivity incidence incidence rate Inclusion inclusion and exclusion criteria inclusion criteria Infection Informed consent initial investigator investigator-initiated investigators Japan Japanese LAMP limit log-rank test male Mild mild COVID-19 patient Mild disease mixed-effects model multicenter Nasopharyngeal swab Negative conversion Negative PCR nelfinavir null hypothesis number objective Open-label outcome oxygen Oxygen administration p value parallel group parameter participant Patient patients with asymptomatic PCR PCR test Pneumonia power Pregnancy primary endpoint Primary outcome principal investigator Probability probability distribution protocol random randomization Randomized Randomized controlled trial Registered registry reported required respiratory tract rifampicin room air safety endpoint Saliva saliva samples Sample size SARS-CoV-2 SARS-CoV-2 vaccination secondary efficacy endpoint serious complication serum creatinine severity specimen Standard status study period Study protocol supplementary material survival survival function Symptom symptomatic symptomatic COVID-19 Symptomatic treatment the log-rank test Three times daily Treatment treatment for HIV treatment period Trial Trial registration two-sided Unsuitable Viral viral dynamics Viral load virus was determined website Withdrawal withdrawal of consent [DOI] 10.1186/s13063-021-05282-w PMC 바로가기 [Article Type] Letter
The Significance of Phenotyping and Quantification of Plasma Extracellular Vesicles Levels Using High-Sensitivity Flow Cytometry during COVID-19 TreatmentCOVID-19 치료 중 고감도 유세포 분석을 사용한 혈장 세포외 소포 수준의 표현형 및 정량화의 중요성Brief Report Published on 2021-04-272022-09-01 Journal: Viruses [Category] MERS, SARS, 바이오마커, 진단, [키워드] CD14 CD14+ CD146 CD147 CD19 CD19+ CD4+ CD63 CD8+ cell type cell types centrifugation clinical manifestation Concentration Coronavirus infection COVID-19 demonstrated diagnostics differential centrifugation dissemination Effectiveness EVs Exosomes extracellular vesicle Extracellular vesicles Flow flow cytometry high-sensitivity flow cytometry immunostaining Infection Level marker mechanism New Pathogenesis patients with moderate Phenotyping phenotyping extracellular vesicles plasma plasma extracellular vesicles Plasma level Plasma levels progression Quantitative analysis SARS-CoV-2 Severe infection severity Significance significantly increased therapy transfer Vesicle vesicles [DOI] 10.3390/v13050767 PMC 바로가기 [Article Type] Brief Report
Review of the Microbiological Diagnostic Approaches of COVID-19Public Health Published on 2021-04-272022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Accuracy approaches circulation COVID-19 COVID-19 disease cross-reactivity diagnoses diagnostic diagnostic test diagnostic testing dissemination elapsed immunoassay Laboratory nucleic acid test optimizing diagnostics pandemic Prevent protocol provided review RT-PCR SARS-CoV-2 sensitivity Spread symptom onset Taking the WHO variable virus WHO World Health Organization [DOI] 10.3389/fpubh.2021.592500 PMC 바로가기 [Article Type] Public Health