Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma
Research
[키워드] ACE2
angiotensin
Asthma
biopsies
biopsy
Blood
body mass index
clinical parameter
Clusters
Cohort
Corticosteroid
COVID-19 disease
enzyme
European
examined
expressed
expression
expression level
functions
furin
FURIN gene
Gender
Gene Expression
greater
host cells
inflammasome activation
Inflammation
inflammatory cells
Invasion
Level
lung
male
Microarray
molecular
molecular phenotype
morbidity and mortality
mRNA expression
multivariate analyses
neutrophil
neutrophilic
Neutrophils
outcome
oxidative phosphorylation
Phenotypes
protease
Proteases
Result
risk
SARS-COV-2 infection
serine 2
Severe asthma
severity
significantly
significantly higher
significantly increased
sputum
TMPRSS2
TMPRSS2 level
transmembrane
Type
[DOI] 10.1186/s12931-020-01605-8 PMC 바로가기 [Article Type] Research
[DOI] 10.1186/s12931-020-01605-8 PMC 바로가기 [Article Type] Research