Wild Ducks as Long-Distance Vectors of Highly Pathogenic Avian Influenza Virus (H5N1)Research Published on 2008-04-012023-05-31 Journal: Emerging Infectious Diseases [Category] Fulltext, 조류인플루엔자, [키워드] disease vectors Ducks Epidemiology H5N1 subtype immunohistochemistry influenza A virus influenza in birds pathology Research Reverse transcriptase polymerase chain reaction Virology [DOI] 10.3201/eid1404.071016 PMC 바로가기 [Article Type] Research
Hemagglutinating Encephalomyelitis Coronavirus Infection in Pigs, ArgentinaDispatch Published on 2008-03-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] caused coronavirus dispatch Encephalomyelitis Epidemiology Factors genomic sequence genomic sequencing immunohistochemistry Infection outbreak pathologic features pathology porcine hemagglutinating encephalomyelitis coronavirus RT-PCR South America syndrome vomiting [DOI] 10.3201/eid1403.070825 PMC 바로가기 [Article Type] Dispatch
Functional Genomics Highlights Differential Induction of Antiviral Pathways in the Lungs of SARS-CoV–Infected MacaquesResearch Article Published on 2007-08-102022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] activate activated acute phase acute respiratory distress acute respiratory syndrome Admission Adult against SARS-CoV analyzed Antiviral antiviral signaling Atypical Author cause Cell cells characterized chemokine genes chemokines circumvent Complication coronavirus Critical cynomolgus macaque cytokine demonstrated early IFN signaling Effect event examined functional gene expression profile gene signature Genomics highlight Host host response IFNs IL-8 immune response immunohistochemistry in vitro experiments individuals induction Infection innate immune response Innate immunity intensive care involved IP-10 lung Lung pathology macaque macaques nuclear translocation Pathogenesis pathogenic pathway phosphorylated Pneumonia protective immune response regulated required SARS patient SARS-CoV SARS-CoV infection SARS-CoV–infected cells severe shown Stat1 subset syndrome Transcription transcription factor type I interferon viral infection virus virus replication [DOI] 10.1371/journal.ppat.0030112 PMC 바로가기 [Article Type] Research Article
Time Course and Cellular Localization of SARS-CoV Nucleoprotein and RNA in Lungs from Fatal Cases of SARSResearch Article Published on 2006-02-032022-10-29 Journal: PLoS Medicine [Category] Coronavirus, MERS, [키워드] 2003 acute respiratory syndrome alveolar alveolar epithelium antiviral therapy appear assay association Autopsy Canada case cellular China Clinical course clinical disease collected compared coronavirus detected died disease etiological Evidence finding Hong Kong humans illness onset immunohistochemistry In situ Infected involved knowledge less Localization lung lung tissue Lungs Macrophage macrophages monoclonal antibody nucleoprotein outbreak Pathogenesis Patient patients with SARS pneumocyte Pulmonary pathology Region Replication RNA SARS Coronavirus SARS-CoV Seven symptom onset target the disease time Toronto Treatment viral infection virus widespread [DOI] 10.1371/journal.pmed.0030027 PMC 바로가기 [Article Type] Research Article
Generation of human antibody fragments recognizing distinct epitopes of the nucleocapsid (N) SARS-CoV protein using a phage display approachResearch Article Published on 2005-09-192022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, [키워드] acute respiratory syndrome antibody antibody fragment Antiviral compound approach cause characterized coated with antigen described detect diagnostic test disease domain ELISA epitope Generation high mortality rate Human immunocytochemistry immunohistochemistry in vitro Infected Isolation MONITOR N protein neutralizing antibody nucleocapsid Particle Prevent Protein reagent recognize recognizing Result SARS epidemic SARS virus SARS-CoV SARS-CoV N protein scFv selected severe Spread target cells treat Vaccine Vero cells virus was used [DOI] 10.1186/1471-2334-5-73 PMC 바로가기 [Article Type] Research Article
Monkeypox Transmission and Pathogenesis in Prairie DogsResearch Published on 2004-03-012023-06-09 Journal: Emerging Infectious Diseases [Category] Fulltext, 원숭이두창, [키워드] electron microscopy immunohistochemistry Monkeypox virus pathology PCR prairie dog Transmission [DOI] 10.3201/eid1003.030878 PMC 바로가기 [Article Type] Research