Pre-Vaccine Positivity of SARS-CoV-2 Antibodies in Alberta, Canada during the First Two Waves of the COVID-19 PandemicCOVID-19 팬데믹의 첫 두 물결 동안 캐나다 앨버타주에서 SARS-CoV-2 항체의 백신 사전 양성Research Article Published on 2021-08-182022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] 95% CI 95% confidence interval antibodies antibody best blood sample Canada clinical laboratories Cohort collected Concordance correlated correlation COVID-19 COVID-19 pandemic demographics detectable Epidemiology evaluated facilitate female followed by geographical areas group help highest highlight immunology in some individual Infection information Laboratory Local lowest male minority groups molecular molecular test NAAT no significant difference nucleic acid test nucleocapsid protein Patient population prevalence positive positive COVID-19 proportion provide public health residual SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 nucleocapsid SARS-CoV-2 virus second wave secondary school seeking serology serology testing seronegative seropositive seropositive individual seropositive individuals Seropositivity Seroprevalence Sociodemographic Spike protein Support tested the SARS-CoV-2 virus vaccination Wave [DOI] 10.1128/Spectrum.00291-21 PMC 바로가기 [Article Type] Research Article
Digital Orientation of Health Systems in the Post–COVID-19 “New Normal” in the United States: Cross-sectional SurveyOriginal Paper Published on 2021-08-162022-10-30 Journal: Journal of Medical Internet Research [Category] Coronavirus, MERS, SARS, [키워드] absence Analysis assessment Care Characteristics collected compendium Consensus country COVID-19 COVID-19 pandemic cross-sectional dataset difference Digital Digital health digital orientation digital transformation dimension discharge rate effort EHR Electronic health record estimate examined executive facilitator Factor growth Health health system health systems hospital Impact imperative insight lack less Logistic lowest medium notable objective Orientation Other Periodic Post–COVID-19 provided Quality raising reported Result robust secondary survey System telehealth Telemedicine the United State The United States United States Virtual care were assessed [DOI] 10.2196/30453 PMC 바로가기 [Article Type] Original Paper
Analysing the reported incidence of COVID-19 and factors associated in the World Health Organization African region as of 31 December 2020Original Paper Published on 2021-08-162022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, MERS, SARS, [키워드] adjust adjusted African African region analysed Analysing binomial regression models Cape confirmed case country COVID-19 cumulative epidemiological Factor Health health systems highest highlight incidence incidence of COVID-19 Increasing lowest member Niger performed populations proportion recorded reported SARS-CoV-2 test South Africa state the WHO World Health Organization [DOI] 10.1017/S095026882100193X PMC 바로가기 [Article Type] Original Paper
Molecular docking and dynamic simulation of conserved B cell epitope of SARS-CoV-2 glycoprotein Indonesian isolates: an immunoinformatic approachResearch Article Published on 2021-08-162022-10-31 Journal: F1000Research [Category] COVID-19, MERS, SARS, [키워드] Activation acute respiratory syndrome addition Antigen antigenic approach B cell B cell epitope BCR binding Brazil calculated Candidates carried CD4+ cell China complex conserved conserved region. coronavirus country COVID-19 differentiation docking epitope gene sequence GISAID histocompatibility complex HLA Immunoinformatic India Indonesia Infectious disease investigated isolate isolates leukocyte lowest memory response MHC-II molecular NCBI non-toxic peptide predicted produced receptor Region SARS-CoV-2 SARS-CoV-2 glycoprotein SARS-CoV-2 isolate SARS-CoV-2 spike glycoprotein sequence South Africa spike glycoprotein T cell The United States the vaccine Toxicity United Kingdom Vaccine vaccine candidate Virus neutralization Wuhan [DOI] 10.12688/f1000research.54258.1 PMC 바로가기 [Article Type] Research Article
Phase I dose-escalation single centre clinical trial to evaluate the safety of infusion of memory T cells as adoptive therapy in COVID-19 (RELEASE)Research article Published on 2021-08-132022-10-05 Journal: EClinicalMedicine [Category] 임상, [키워드] Antigen can be used Cell clinical Clinical research clinical status clinical trial conducted convalescent COVID-19 COVID-19 patient development Donor dose dose-escalation European evaluate Evidence feasibility feasible finding foundation funding highest dose HLA Hospitalization Immunotherapy infused intermediate dose leukocyte lowest lymphocyte lymphopenia memory memory T cell memory T cells Mortality network parameter participant patients phase Pneumonia provide reduce Regional reported Safe SARS-CoV-2 score Serious Adverse Event severity of symptoms Spanish subject supported Symptom T cell T-lymphocyte therapy Treatment [DOI] 10.1016/j.eclinm.2021.101086 [Article Type] Research article
Entropy and Fractal Dimension Study of the TDP-43 Protein Low Complexity Domain Sequence in ALS Disease Severity and SARS-CoV-2 Gene Sequences in Virulence VariabilityArticle Published on 2021-08-122022-10-31 Journal: Information Sciences [Category] COVID-19, [키워드] ALS Amino acid Analysis Cell codon usage complexity computational analysis computational method conducted correlation coefficient cryo-EM defined described dimension domain Entropy extreme Fractal Fractal dimension gene sequence Genes HAR1 highest information low complexity domain sequence lowest nucleotide produced Protein protein sequence reported SARS-CoV-2 sequence TDP-43 Vaccine design viability virulence virulent Znf521 [DOI] 10.3390/e23081038 PMC 바로가기 [Article Type] Article
Psychosocial distress amongst Canadian intensive care unit healthcare workers during the acceleration phase of the COVID-19 pandemicResearch Article Published on 2021-08-122022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] Anxiety asked Canada Care cohort study conducted COVID-19 COVID-19 pandemic COVID-19 patient cross-sectional Depression distress emerging disease examined Factor female First wave France Frequency GHQ-12 HCW Healthcare system healthcare worker highest hospital ICU infected with COVID-19 intensive care lowest majority male mental health mental health issue multivariable number numbers of patient Outbreaks pandemic participant Personal protective equipment physician positive PPE Psychosocial questionnaire registered nurse regression analysis reported required response risk scored Strategy Stress Support Symptom with COVID-19 [DOI] 10.1371/journal.pone.0254708 PMC 바로가기 [Article Type] Research Article
Transmission dynamics of SARS-CoV-2 in a mid-size city of ChinaResearch Article Published on 2021-08-102022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome addition affected Asymptomatic carrier asymptomatic patient asymptomatic patients basic reproductive number case sery characteristic Characteristics China Chinese Clinical characteristics Contact coronavirus cough country COVID-19 described effective epidemiological evaluated example female global pandemic had no help individual Intervention lowest median age outbreak pandemic Patient Pneumonia Prevention and control measures Public health intervention R0 Rt reached Reproduction number Result SARS-CoV-2 SARS-CoV-2 transmission spread to supplementary material Symptom Symptoms the epidemic the patient Transmission Transmission dynamics Wuhan [DOI] 10.1186/s12879-021-06522-9 PMC 바로가기 [Article Type] Research Article
Virtual screening of plant-derived compounds against SARS-CoV-2 viral proteins using computational tools컴퓨터 도구를 사용한 SARS-CoV-2 바이러스 단백질에 대한 식물 유래 화합물의 가상 스크리닝Article Published on 2021-08-102022-09-11 Journal: The Science of the total environment [Category] SARS, 치료제, [키워드] 3-chymotrypsin-like protease addition amyrin antiviral activity Atazanavir AutoDock binding Chloroquine chymotrypsin Chymotrypsin-like protease Compound computational tool Control COVID-19 COVID-19 pandemic delphinidin dicumarol docking Docking studies drug evaluate evaluated explain glycoprotein Glycyrrhetinic acid glycyrrhizin highest affinity host cell host cells hydrogen Hydrogen bond hydrophobic hydrophobic interaction hydrophobic interactions Hydroxychloroquine identify in viral inhibitor Interaction involved lowest M pro molecular molecular docking molecular target nelfinavir new SARS-CoV-2 plants protease Protein Proteins public health Recognition Replication responsible S protein SARS-CoV-2 SARS-CoV-2 viral SARS-CoV2 spike spike glycoprotein taraxasterol target umifenovir Viral protein Viral proteins viral replication viral spike virus was performed were used [DOI] 10.1016/j.scitotenv.2021.146400 PMC 바로가기 [Article Type] Article
The Environmental and Social Determinants of Health Matter in a Pandemic: Predictors of COVID-19 Case and Death Rates in New York CityArticle Published on 2021-08-092022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] Analysis analyzed boroughs case rates Characteristics Community coronavirus coronavirus disease COVID-19 COVID-19 case death rate death rates determinant determine Environment Factor Government Health highest highlight Impact include Inequities Intervention lowest Manhattan matter New York City ozone level pandemic Predictive predictor proportion Rate reduce reported Research Result Significant social determinant social determinants of health unique white [DOI] 10.3390/ijerph18168416 PMC 바로가기 [Article Type] Article