Copan eNAT Transport System To Address Challenges in COVID-19 Diagnostics in Regions with Limited Testing AccessCopan eNAT Transport System, 테스트 접근이 제한된 지역의 COVID-19 진단 문제 해결Virology Published on 2021-02-122022-09-12 Journal: Journal of Clinical Microbiology [Category] MERS, 진단, [키워드] absence access Accuracy address biosafety Brescia can not Care Cell culture Cepheid Cepheid Xpert Xpress SARS-CoV-2 challenge clinics cold chain compatibility condition coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 testing cycle threshold demonstrated diagnostic Diagnostic accuracy diagnostics eNAT evaluated expand handling Health Health care hospital implementation Italy Limited limited testing access low-resource settings lysate medium molecular nasopharyngeal PBS phosphate phosphate-buffered saline point of care reduced Region regions respiratory respiratory virus rural areas rural healthcare Saline SARS-CoV-2 SARS-CoV-2 inactivation SARS-CoV-2 specimen stability sensitivity specimen specimen stability stability Support syndrome System temperature Testing Transport Transport media transport medium Viral viral inactivation Viral transport medium VTM [DOI] 10.1128/JCM.00110-21 PMC 바로가기 [Article Type] Virology
Experimental data using candesartan and captopril indicate no double-edged sword effect in COVID-19칸데사르탄과 캡토프릴을 사용한 실험 데이터는 COVID-19에서 양날의 검 효과가 없음을 나타냅니다Article Published on 2021-02-122022-09-11 Journal: Clinical Science (London, England : 1979) [Category] 유전자 메커니즘, [키워드] ACE ACE2 ACE2 expression ACEi ACEIs ADAM17 angiotensin angiotensin-converting enzyme 2 Anti-inflammatory anti-inflammatory response antihypertensives. ARB ARBs AT1 AT2 blood pressure candesartan Captopril Cell cells change COVID-19 Culture culture medium cultures Cytokines decrease drug drugs entry receptor expression full-length healthy hyperglycemia increase increase in inhibited lung mechanisms medium metabolic syndrome obesity Patient pneumocyte Proinflammatory cytokine proinflammatory cytokines promote RAS RAS activity RATs receptor receptor blocker receptors regulate Renin renin-angiotensin system severe COVID-19 soluble ACE2 spike Spike protein syndrome tissue transmembrane up-regulated up-regulation Viral viral entry viral spike protein virus [DOI] 10.1042/CS20201511 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Subgenomic N ( sgN ) Transcripts in Oro-Nasopharyngeal Swabs Correlate with the Highest Viral Load, as Evaluated by Five Different Molecular MethodsArticle Published on 2021-02-122022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] amplification applied assays Biomarker CE-IVD COVID-19 pandemic detect diagnostic diagnostics digital PCR Dilution Effects evaluated FIVE genomic IMPROVE information Laboratory load marker medium molecular test PBS question ranged RdRP replicate representing respond Result RNA RNA transcript RT-qPCR SARS-CoV-2 SARS-CoV-2 subgenomic regions SARS-CoV-2 viral Severe infection Spread subgenomic transcript swabs target target gene TMB transcript Viral load [DOI] 10.3390/diagnostics11020288 PMC 바로가기 [Article Type] Article
COVID-19 Vaccination Acceptance and Its Associated Factors Among a Middle Eastern PopulationPublic Health Published on 2021-02-102022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, [키워드] acceptance anticipated applied asked association Attitude category CDC center Characteristics Control Coronavirus disease 2019 COVID-19 COVID-19 complications COVID-19 symptoms COVID-19 virus cross-sectional effective effort enrolled evaluate evaluated Factor groups high risk identify Intention KAP knowladge knowledge knowledge score lack Measures median medium middle multinomial logistic regression overcome pandemic participant Population Practice predictor prevention Protective public health refusal regressions reported risk Sample sample characteristics the vaccine Transmission vaccination Vaccine web-based study were assessed were infected [DOI] 10.3389/fpubh.2021.632914 PMC 바로가기 [Article Type] Public Health
A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and bloodResearch Article Published on 2021-02-032022-10-04 Journal: Science Advances [Category] MERS, 유전자 메커니즘, [키워드] Accuracy acute respiratory syndrome Bacterial sepsis Biomarker Blood can be used cause Classifier clinically Complete controls coronavirus Coronavirus disease-19 COVID-19 COVID-19 diagnosis COVID-19 disease diagnose diagnostic Differentially expressed genes down-regulation elicit exhibited Genes global pandemic hospitalized patient Host host response immune response independent Infection Inflammatory response Influenza medium nasal swab nasopharyngeal NP swab Outpatient paradoxical Pathways Patient patients with COVID-19 RNA RNA sequencing robust SARS-CoV-2 SARS-COV-2 infection seasonal coronaviruses Swab [DOI] 10.1126/sciadv.abe5984 PMC 바로가기 [Article Type] Research Article
Expected Medium- and Long-Term Impact of the COVID-19 Outbreak in Oncology종양학에서 COVID-19 발생의 중장기적 영향 예상SPECIAL ARTICLES Published on 2021-02-022022-09-10 Journal: JCO Global Oncology [Category] MERS, 임상, [키워드] activities activity affected clinical activity clinical trial compensated country COVID-19 COVID-19 outbreak COVID-19 pandemic Europe expected geographical areas healthcare Healthcare system Healthcare systems Impact increasingly infected patients International introduced Latin America Local medium National nine oncologist oncology palliative treatment participant Participants participated Patient performed positive patients reduced reduction reorganization reported Research Significant surgery Telemedicine Treatment United State United States Well-being [DOI] 10.1200/GO.20.00589 PMC 바로가기 [Article Type] SPECIAL ARTICLES
Evaluating contaminated dental aerosol and splatter in an open plan clinic environment: Implications for the COVID-19 pandemic개방형 클리닉 환경에서 오염된 치과용 에어로졸 및 튀김 평가: COVID-19 전염병에 대한 시사점Article Published on 2021-02-012022-09-11 Journal: Journal of dentistry [Category] Coronavirus, 치료기술, [키워드] aerosol Aerosols appear benefit clinic clinical Clinical significance clinics conditions Contamination COVID-19 pandemic dental Dental equipment Dental fallow time Dental high-speed equipment Dental infection control dental procedures detectable distribution Effect Evaluating experimental design Filter Paper filter papers Fluorescein fluorescein dye head Infection majority mannequin medium MOST mouth open produced reduced retained risk SARS-CoV-2 suction Ventilation Volume was used water [DOI] 10.1016/j.jdent.2020.103565 PMC 바로가기 [Article Type] Article
Disease Severity, Fever, Age, and Sex Correlate With SARS-CoV-2 Neutralizing Antibody Responses질병 중증도, 발열, 연령 및 성별은 SARS-CoV-2 중화 항체 반응과 관련이 있습니다Immunology Published on 2021-01-292022-09-12 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, [키워드] affecting age analyzed Anosmia Antibody deficiency approach benefit Biosafety Level 3 clinical Clinical data convalescent plasma Coronavirus disease 2019 COVID-19 COVID-19 convalescent patients deficiency Donor donors Efficacy ELISA testing Evidence Factor Fever Hospitalization immunodeficiency Inconclusive increasingly Laboratory Logistic regression analysis logistic regression model medium Mortality Neutralizing antibodies neutralizing antibody Odds ratio P -value Patient plaque reduction neutralization Plaque reduction neutralization test plasma Predictive PRNT PRNT50 response SARS-CoV-2 SARS-CoV-2 neutralizing antibody secondary antibody Sex single center subgroup analysis symptom onset Trial true positive variable while [DOI] 10.3389/fimmu.2020.628971 PMC 바로가기 [Article Type] Immunology
Control and prevention of infectious diseases from a One Health perspectiveArticles Published on 2021-01-292022-10-31 Journal: Genetics and Molecular Biology [Category] COVID-19, [키워드] Community Contact Control COVID-19 pandemic Disease progression Diseases ecosystem effective environmental factor Epidemics global health highlight Human genetics hygiene Impact Infection Infectious disease medium one health outbreak Outbreaks Pandemics pathogen Perspective Prevent public health reduction reduction in Safe Sex suggested susceptibility the SARS-CoV-2 translational transmitted Treatment [DOI] 10.1590/1678-4685-GMB-2020-0256 PMC 바로가기 [Article Type] Articles
The use of the online Inverted Classroom Model for digital teaching with gamification in medical studiesArticle Published on 2021-01-282022-11-01 Journal: GMS Journal for Medical Education [Category] Coronavirus, [키워드] activated activating Care classroom Course COVID-19 pandemic Emergency game-based learning Gamification German health system Health health systems ICAP model implementation Inverted Kahoot! medical education medium Model online Inverted Classroom Model Passive Patient Perspective promote public health question remained remote resulting subject synchronous Teaching the patient [DOI] 10.3205/zma001399 PMC 바로가기 [Article Type] Article