Outcomes Evaluated in Controlled Clinical Trials on the Management of COVID-19: A Methodological Systematic ReviewArticle Published on 2020-12-152022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] adverse event clinical Clinical practice Clinicians Community comparability Controlled coronavirus disease Coronavirus disease 2019 COVID-19 Critical endpoints evaluate evaluated facilitate greater heterogeneity heterogeneous Hospital admission Hospitalized intensive care less management methodological Mortality outcome outcomes Patient Randomized controlled trial Randomized controlled trials RCT RCTs Registered reported review selected Significant systematic review systematic reviews Treatment trial methods trials [DOI] 10.3390/life10120350 PMC 바로가기 [Article Type] Article
Corticosteroid use in COVID-19 patients: a systematic review and meta-analysis on clinical outcomesResearch Published on 2020-12-142022-11-01 Journal: Critical Care [Category] COVID-19, MERS, [키워드] 28-day mortality 95%CI antibiotic use benefit Clinical outcome coronavirus Corticosteroid Corticosteroids COVID-19 Dexamethasone Effectiveness evaluate Hospital stay increase in Infection mechanical ventilation Meta-analysis Mortality objective observational study outcome Oxygen therapy Patient patients positive quantified ranged RCT RCTs RECOVERY trial reduced reduction in reported respiratory specimens Result RT-PCR SARS-CoV-2 SARS-CoV-2 pandemic secondary secondary infections shown Standard of care systematic literature search systematic review use of corticosteroid viral clearance was performed Web of Science [DOI] 10.1186/s13054-020-03400-9 PMC 바로가기 [Article Type] Research
Efficacy and harms of remdesivir for the treatment of COVID-19: A systematic review and meta-analysis코로나19 치료를 위한 렘데시비르의 효능과 유해성: 체계적인 검토 및 메타분석Meta-Analysis Published on 2020-12-102022-09-10 Journal: PLoS ONE [Category] SARS, 임상, 치료제, [키워드] 95%CI all-cause mortality analyzed can not case sery clinical Clinical improvement COVID-19 decrease disease Effect Efficacy and safety Evidence heterogeneity high risk hospitalized COVID-19 hospitalized COVID-19 patients Intravenous remdesivir invasive ventilation inverse meta-analyses Meta-analysis nine no differences outcome performed Placebo Primary outcomes random effect Randomized controlled trial RCT RCTs regimen Remdesivir reported Result SAE SAEs searched Serious Adverse Event Serious Adverse Events severity Standard of care systematic review therapy time treating COVID-19 Treatment treatment of COVID-19 [DOI] 10.1371/journal.pone.0243705 PMC 바로가기 [Article Type] Meta-Analysis
Community use of face masks and similar barriers to prevent respiratory illness such as COVID-19: a rapid scoping reviewReview Published on 2020-12-102022-10-31 Journal: Eurosurveillance [Category] COVID-19, MERS, SARS, [키워드] assessment attack rate Cohort Community Control coronavirus cross-sectional study described development Effect Effectiveness Effects Evidence Face mask Hajj improvement incidence influenza-like-illness lowest Mask Meta-analysis narrative observational study Odds ratio outcome performed poor compliance Prevent Primary infection PROTECT random-effect randomised RCT RCTs reduce reduced required Respiratory disease Respiratory illness respiratory infection Result risk searched secondary attack rate suggested Trial wearing wearing face mask wearing masks while [DOI] 10.2807/1560-7917.ES.2020.25.49.2000725 PMC 바로가기 [Article Type] Review
Convalescent plasma may be a possible treatment for COVID-19: A systematic reviewReview Published on 2020-12-052022-10-04 Journal: International immunopharmacology [Category] MERS, SARS, 치료법, 치료제, [키워드] 95% CI 95%CI adverse events analyzed anti-inflammatory compounds antivirals article articles assessment Blood Care children China clinical Clinical symptoms Cochrane Library conducted control group convalescent Convalescent plasma therapy Convalescent plasma(CP) coronavirus disease Coronavirus disease 2019(COVID-19) COVID-19 criteria determine effective Efficacy evaluate Evidence exclusion Final help identify immune Immunocompromised patients immunoglobulins Immunotherapy IMPROVE incidence Inclusion involved lack MERS-CoV Meta-analysis moderate Novel coronavirus Other pandemic Patient patients with COVID-19 performed plasma pregnant protocol RCT reduce mortality reducing reported resource Result risk of bia SARS-CoV SARS-CoV-2 second serious AEs serum significantly Spread statistically significant difference suggested systematic review the disease the epidemic therapy therapy for COVID-19 Treatment Vaccine viral infection virus was performed were used [DOI] 10.1016/j.intimp.2020.107262 PMC 바로가기 [Article Type] Review
A multicenter, randomized, open-label, controlled trial to evaluate the efficacy and tolerability of hydroxychloroquine and a retrospective study in adult patients with mild to moderate coronavirus disease 2019 (COVID-19)하이드록시클로로퀸의 효능과 내약성을 평가하기 위한 다기관, 무작위, 공개, 대조 시험 및 2019년 경증에서 중등도의 코로나바이러스 질환(COVID-19)을 앓고 있는 성인 환자를 대상으로 한 후향적 연구Randomized Controlled Trial Published on 2020-12-022022-08-13 Journal: PLoS ONE [Category] 임상, [키워드] 95% CI Administered collected control group Controlled trial coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis demonstrated Diagnosis Efficacy evaluate evaluated groups HCQ hospital Hydroxychloroquine medical record medical records Mild mild to moderate moderate Moderate COVID-19 multicenter objective Open-label Patient PCR pharyngeal proportion Public Hospital randomization Randomized Randomized controlled trial RCT real-time RT-PCR Result Retrospective study rRT-PCR SARS-CoV-2 sputum Standard of care stratified subject subjects Swab Taiwan the median Tolerability Viral viral shedding virus were assessed with COVID-19 [DOI] 10.1371/journal.pone.0242763 PMC 바로가기 [Article Type] Randomized Controlled Trial
A systematic review of corticosteroid treatment for noncritically ill patients with COVID-19Article Published on 2020-12-012022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 임상, 치료기술, 치료법, [키워드] Abstract association Corticosteroid corticosteroid treatment COVID-19 COVID-19 therapy Critical Critical case Diseases Evidence FIVE Guidance Hospitalization ill patient in-hospital mortality intubation Medical research Mild moderate Mortality observational studies observational study outcome outcomes oxygen Patient patients propensity score matching Randomized controlled trial RCT RCTs recommendation recovery RECOVERY trial reduced risk screened Seven statistical significance Support systematic review systemic corticosteroid the WHO Treatment Trial viral shedding WHO with COVID-19 World Health Organization [DOI] 10.1038/s41598-020-78054-2 PMC 바로가기 [Article Type] Article
Comparing the impact of Hydroxychloroquine based regimens and standard treatment on COVID-19 patient outcomes: A retrospective cohort studyResearch article Published on 2020-12-012022-10-05 Journal: Saudi Pharmaceutical Journal : SPJ [Category] 치료법, [키워드] Abdul adjusted Admission age age and gender anti-inflammatory drug Antiviral Aziz cohort study conducted coronavirus disease COVID-19 COVID-19 patient discharge Effectiveness Efficacy eligible evaluate generalized linear regression HCQ hospital Hospital stay Hospitalization Hospitalized Hydroxychloroquine ICU ICU admission inclusion criteria investigated knowledge laboratory-confirmed Length less Logistic regression Lopinavir/ritonavir mechanical ventilation Mild Ministry of Health moderate no significant difference observational study outcome outcomes Patient patients with COVID-19 previous study Prince protocols RCT regimen regression analysis Result retrospective cohort study Saudi Arabia standard care standard treatment treated Treatment treatment for COVID-19 two group variables [DOI] 10.1016/j.jsps.2020.09.019 [Article Type] Research article
Hydroxychloroquine for prophylaxis of COVID-19 physicians survey: Despite lack of evidence, many would take or give to dear ones, and despite the perceived necessity of an RCT, few would participate코로나19 예방을 위한 하이드록시클로로퀸 내과의사 설문조사: 근거 부족에도 불구하고 많은 사람이 소중한 사람에게 받거나 주고, RCT의 필요성 인식에도 불구하고 소수 참여Article Published on 2020-12-012022-09-11 Journal: Journal of Evaluation in Clinical Practice [Category] 치료제, [키워드] administer age asked belief Care collected concerning Controlled trial correlation COVID-19 COVID-19 patients Evidence Facebook family Hydroxychloroquine indicated information involved lack opinion patients performed physician Physicians prophylactically Prophylaxis questionnaire Randomized randomized clinical trial Randomized controlled trial RCT survey thought Treatment treatment for COVID-19 treatment regimen Trial use of hydroxychloroquine [DOI] 10.1111/jep.13484 PMC 바로가기 [Article Type] Article
The Role of Vitamin C as Adjuvant Therapy in COVID-19Internal Medicine Published on 2020-11-302022-10-31 Journal: Cureus [Category] COVID-19, [키워드] adjuvant affected age anti-inflammatory property biochemical Care clinical symptom clinician conducted coronavirus disease COVID-19 COVID-19 patient Gender had no hospital Hospital stay IMPROVE Intervention intravenous vitamin C Karachi mechanical ventilation Mortality no significant difference outcome Pakistan Patient questionnaire Randomized controlled trial RCT recorded required Result role shown significantly Standard therapy therapy Treatment two group two groups Ventilation vitals Vitamin Vitamin C [DOI] 10.7759/cureus.11779 PMC 바로가기 [Article Type] Internal Medicine