COVID-19 diagnosis by SARS-CoV-2 Spike protein detection in saliva using an ultrasensitive magneto-assay based on disposable electrochemical sensorResearch article Published on 2022-02-012022-10-05 Journal: Sensors and Actuators B: Chemical [Category] 유전자 메커니즘, 치료기술, [키워드] ACE2 Analysis applied caused coronavirus 2 COVID-19 COVID-19 diagnosis COVID-19 pandemic develop diagnosing diagnostic test disease early diagnosis Efficiency eight Electrochemical Device exhibited Gold nanoparticle healthy human Angiotensin-converting enzyme human saliva involved less limit of detection limitation magnetic bead outbreak peptide point-of-care Protein reduction respiratory RT-PCR Saliva SARS-CoV-2 SARS-CoV-2-infected individuals sensitivity similarity specificity spike Spike protein the disease Viral transmission was tested [DOI] 10.1016/j.snb.2021.131128 [Article Type] Research article
CPC-containing oral rinses inactivate SARS-CoV-2 variants and are active in the presence of human salivaArticle Published on 2022-02-012023-07-08 Journal: Journal of Medical Microbiology [Category] COVID19(2023년), [키워드] COVID-19 Mouthwash Oral hygiene Saliva SARS-CoV-2 [DOI] 10.1099/jmm.0.001508 PMC 바로가기
Alternative SARS-CoV-2 detection protocol from self-collected saliva for mass diagnosis and epidemiological studies in low-incoming regions유입량이 적은 지역의 대량 진단 및 역학 연구를 위한 자가 수집 타액의 대체 SARS-CoV-2 검출 프로토콜Article Published on 2022-02-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95 % CI ABC acute respiratory syndrome adopted Betacoronavirus Chain Reaction circulation cotton develop diagnosed Diagnosis diagnostic Diagnostic Criteria Diagnostic method diagnostic protocol Endpoint epidemiological studies Epidemiological study evaluated foci healthcare facility hydrophilic initial Laboratory Local mass vaccination material medical school Molecular diagnosis nasopharynx pandemic Patient polymerase chain polymerase chain reaction positive protocol qRT-PCR Quantitative Region regions RT-endpoint-PCR Saliva saliva samples sample collection SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 qRT-PCR School Severe acute respiratory syndrome social distancing Support the SARS-CoV-2 Transmission vaccination Viral RNA viral RNA detection virus [DOI] 10.1016/j.jviromet.2021.114382 PMC 바로가기 [Article Type] Article
Rapid detection of novel coronavirus SARS-CoV-2 by RT-LAMP coupled solid-state nanoporesRT-LAMP 결합 고체 나노 기공에 의한 신종 코로나바이러스 SARS-CoV-2의 신속한 검출Article Published on 2022-02-012022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 adopted Amplicon amplification capture caused clinical copy number Coronavirus-2 COVID-19 disease spread Early detection event rate Genes gold gold standard intrinsic Nanopore Nasopharyngeal swab novel coronavirus SARS-CoV-2 nucleocapsid pandemic of COVID-19 platform point-of-care positive public health raised Rapid respiratory RT-LAMP RT-PCR assay Saliva saliva samples SARS-CoV-2 SARS-CoV-2 detection sensitivity Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Solid-state nanopore. Spread the disease threshold [DOI] 10.1016/j.bios.2021.113759 PMC 바로가기 [Article Type] Article
Optimal Decision Theory for Diagnostic Testing: Minimizing Indeterminate Classes with Applications to Saliva-Based SARS-CoV-2 Antibody AssaysArticle Published on 2022-01-312022-10-28 Journal: ArXiv [Category] COVID-19, [키워드] Accuracy Analysis antibody application approach approaches average Bathtub Principle classification decision diagnostic effective expressed identify Inconclusive indeterminate labeling less Local lowest multiplex Probability reduction in Saliva SARS-CoV-2 SARS-CoV-2 antibody theory threshold PMC 바로가기 [Article Type] Article
Population wide testing pooling strategy for SARS-CoV-2 detection using salivaResearch Article Published on 2022-01-282022-10-28 Journal: PLoS ONE [Category] COVID-19, SARS, [키워드] analyzed applied average COVID-19 cycle cycle threshold detect diagnosis of COVID-19 diagnostic effective envelope Genes Healthcare professional identify individuals investigated Median viral load nasopharyngeal sample no significant difference Outbreaks Pain patients Population populations positive predicted reaction reading RT-PCR Saliva saliva sample SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV-2 pandemic sensitivity significant difference specificity suggested symptomatic and asymptomatic [DOI] 10.1371/journal.pone.0263033 PMC 바로가기 [Article Type] Research Article
Assessment of a Smartphone-Based Loop-Mediated Isothermal Amplification Assay for Detection of SARS-CoV-2 and Influenza VirusesSARS-CoV-2 및 인플루엔자 바이러스 검출을 위한 스마트폰 기반 루프 매개 등온 증폭 분석 평가Research Published on 2022-01-282022-09-10 Journal: JAMA Network Open [Category] SARS, 변종, 진단, 치료기술, [키워드] Admission age Analysis assessment asymptomatic patient blinded Can CDC center Chain Reaction circulating variants clinically cohort study Community Concordance Control Cottage Cottage hospital country COVID-19 criterion Critical detect detection diagnostic disease control eligible participant enrolled equipment exhibited exposure finding hospitalized patient hospitalized patients human saliva Importance Influenza influenza A influenza infection Influenza virus influenza viruses isothermal amplification LAMP Loop-mediated isothermal amplification measure men methodology objective offer pandemic participant pathogen Pathogens Patient patients platform Point polymerase chain polymerase chain reaction positive prevention Quantitative reagents recruited Relevance resources Result reverse transcriptase robust RT-qPCR Saliva saliva samples SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 virus screening test screening tests sensitivity setting side SmaRT Smartphone statistical analysis subgroup symptomatic symptomatic and asymptomatic tested Testing variant Viral Viral load virus viruses was performed were used [DOI] 10.1001/jamanetworkopen.2021.45669 PMC 바로가기 [Article Type] Research
Open-source real-time quantitative RT-PCR-based on a RNA standard for the assessment of SARS-CoV-2 viral loadSARS-CoV-2 바이러스 부하 평가를 위한 RNA 표준 기반 오픈 소스 실시간 정량 RT-PCRResearch Article Published on 2022-01-282022-09-10 Journal: Memórias do Instituto Oswaldo Cruz [Category] SARS, 진단, 치료기술, 치료제, [키워드] (RdRp 2019-nCoV assay acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 approach clinical samples Combination Concentration concentrations coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 testing demonstrated detection diagnostics Efficiency evaluated highest identify IMPROVE individual Infection molecular nasopharynx oropharynx plasma samples primer primer pair Quantitative RdRP reaction real-time polymerase chain reaction respiratory reverse primer Reverse transcriptase polymerase chain reaction RNA RNA-dependent RNA polymerase RT-PCR RT-qPCR Saliva SARS-CoV-2 SARS-CoV-2 viral load selected sensitivity Sensitivity and specificity severe acute respiratory syndrome Coronavirus specificity target gene Target genes tested Viral Viral load was performed [DOI] 10.1590/0074-02760210237 PMC 바로가기 [Article Type] Research Article
Oral Pathology in COVID-19 and SARS-CoV-2 Infection—Molecular AspectsCOVID-19 및 SARS-CoV-2 감염의 구강 병리 - 분자 측면Review Published on 2022-01-272022-09-12 Journal: International Journal of Molecular Sciences [Category] 진단, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aerosol Aerosols angiotensin angiotensin converting enzyme article aspect Cell cellular cellular damage Clinical sign Clinical signs contribute coronavirus COVID-19 COVID-19 transmission crevicular fluid data extraction database dental pulp Diagnosis enzyme epithelia evaluate Evidence Express Factor Factors Final Fractions furin Gingiva Health Organization infected patients Infection information Local molecular mucosa oral oral cavity oral mucosa performed periodontium produced Replication respiratory droplet Respiratory droplets Saliva salivary salivary gland SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection SARS-CoV-2 virus Serine severe acute respiratory syndrome Coronavirus Signs and symptoms Spread structures Symptom systemic infection the disease TMPRSS2 tongue transmembrane serine protease transmembrane serine protease 2 Transmission Treatment Type Vaccine virus virus infection virus particle virus particles were used World Health Organization [DOI] 10.3390/ijms23031431 PMC 바로가기 [Article Type] Review
Multiplex Antibody Analysis of IgM, IgA and IgG to SARS-CoV-2 in Saliva and Serum From Infected Children and Their Close Contacts감염된 소아 및 밀접 접촉자의 타액 및 혈청 내 SARS-CoV-2에 대한 IgM, IgA 및 IgG의 다중 항체 분석Immunology Published on 2022-01-272022-09-11 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술, 치료법, [키워드] Adults Affect anti-S IgG antibodies antibody antibody - antigen complex Antigen Barcelona Blood children Clustering analysis complementary Contact correlated correlation COVID-19 determine diagnosed diagnostic evaluate evaluated females field FIVE IgA IgG IgG antibodies IgG antibody IgM Immunity individual infected children infected individual longitudinal study Luminex assay male Non-invasive nucleocapsid Patent pediatric plasma Population positive individual Prevalence Protective Public health interventions RBD response RT-PCR Saliva SARS-CoV-2 SARS-CoV-2 RT-PCR SARS-CoV-2 spike serum serum/plasma significantly higher Spain suggested summer Surveillance symptomatic individuals tested Transmission utility vaccination [DOI] 10.3389/fimmu.2022.751705 PMC 바로가기 [Article Type] Immunology