Head and neck cancer presentations in the emergency department during the COVID-19 pandemic Research Published on 2022-08-052022-10-05 Journal: British dental journal [Category] 치료법, [키워드] analysed Cancer cancers Clinicians Cohort collected COVID-19 pandemic database diagnose Diagnosis disease head lesion management nine Patient presenting Result significantly subsequent suffered the disease Treatment variable [DOI] 10.1038/s41415-022-4505-2 [Article Type] Research
Exploring the Impact of ACE Inhibition in Immunity and Disease면역 및 질병에 대한 ACE 억제의 영향 탐색Review Published on 2022-08-042022-09-11 Journal: Journal of the Renin-Angiotensin-Aldosterone Syste [Category] SARS, 치료기술, [키워드] ACE ACE inhibitor ACE inhibitors aldosterone Alter angiotensin Angiotensin II angiotensin receptor blocker Angiotensin receptor blockers Angiotensin-converting enzyme Antibiotic resistance Antigen presentation ARBs Arthritis Autoimmune autoimmune conditions Autoimmune disease Autoimmune diseases benefit Cancer Complication contribute coronavirus Diseases elevated enzyme highlight human neutrophil human neutrophils Immune cell immune cell populations immune cells immune regulation Immunocompromise Impact implicated independent independent of Infection Inflammation inflammatory immune cell inflammatory immune cells inhibition inhibitor Lupus Macrophage macrophages malignancy neurodegenerative Neutrophils no effect outcome overactive overexpression pandemic Patient phagocytosis RAAS Renin renin-angiotensin-aldosterone system Research responses rheumatoid arthritis risk ROS SARS-CoV2 therapeutic interventions understanding wake Zinc [DOI] 10.1155/2022/9028969 PMC 바로가기 [Article Type] Review
Factors that predict severity of infection and seroconversion in immunocompromised children and adolescents with COVID-19 infectionCOVID-19 감염으로 면역저하된 소아 및 청소년에서 감염 및 혈청전환의 중증도를 예측하는 요인Observational Study Published on 2022-08-032022-09-12 Journal: Frontiers in Immunology [Category] SARS, 임상, 진단, [키워드] Absolute lymphocyte count absolute neutrophil count Analysis ANC anti-SARS-CoV-2 anti-SARS-CoV-2 antibody antibody Antibody Response blood sample body mass index Cancer Cell Chemotherapy children Clinical severity comorbid condition COVID COVID 19 COVID-19 infection Critical Cutoff defined determine died Factor FIVE Hematologic malignancy Hematological malignancy high-risk population Hospitalized ICU Immunocompromised Immunocompromised patient immunosuppressive Infection Laboratory less Level lowest median moderate multivariable model observation outcome outcomes Patient patients PCR Pediatric patient predict Predictive receiving required Respiratory Support SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection Seroconversion seroconversion rate severity Severity of infection stem cell transplant steroid the patient therapy treated univariable vaccination variable was used with COVID-19 [DOI] 10.3389/fimmu.2022.919762 PMC 바로가기 [Article Type] Observational Study
Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics Reviews Published on 2022-08-022022-10-05 Journal: Signal Transduction and Targeted Therapy [Category] 치료제, [키워드] atherosclerotic atherosclerotic lesion benefit Cancer cancers cardiovascular disease cardiovascular diseases cardiovascular event cardiovascular system Cell cholesterol cholesterol homeostasis cholesteryl esters clinics Critical CVD diabetes disease Diseases Disturbed endothelial events Health inhibiting Intervention Lipid Low-Density Lipoprotein cholesterol maintaining mechanism molecular neurodegenerative nonalcoholic fatty liver obesity Osteoporosis pathway preclinical study Prevent PROTECT Regulation regulatory pathways Research shown target Transport Treatment virus infection [DOI] 10.1038/s41392-022-01125-5 [Article Type] Reviews
Effects of lower screening activity during the COVID-19 pandemic on breast cancer patient pathways: Evidence from the age cut-off of organized screening유방암 환자 경로에 대한 COVID-19 범유행 기간 동안 낮은 검진 활동의 영향: 조직 검진의 연령 제한에서 증거Article Published on 2022-08-012022-09-11 Journal: Health policy (Amsterdam, Netherlands) [Category] 치료제, [키워드] age Breast Breast cancer Breast cancer incidence Breast cancer screening Cancer Cancer screening catch caused Combination COVID-19 COVID-19 pandemic cut-off diagnose Diagnosis dropped early diagnosis Effect examined Factors Hungary information mastectomy no significant difference offset old age organized pandemic Partial Partial mastectomy Patient reduction Regression Regression discontinuity. screenings seasonality significant difference Suspension target population Treatment was reduced [DOI] 10.1016/j.healthpol.2022.05.013 PMC 바로가기 [Article Type] Article
Repurposing of anti-lung cancer drugs as multi-target inhibitors of SARS-CoV-2 proteins: An insight from molecular docking and MD-simulation studySARS-CoV-2 단백질의 다중 표적 억제제로서 항폐암 약물의 용도 변경: 분자 도킹 및 MD 시뮬레이션 연구로부터의 통찰력Article Published on 2022-08-012022-09-11 Journal: Microbial pathogenesis [Category] COVID19(2023년), SARS, 신약개발, [키워드] Analysis binding affinity binding energy Cancer Capmatinib conformational change COVID-19 drug Dynamics evaluate Glycoproteins highest binding affinity inhibitors of SARS-CoV-2 molecular docking molecular docking studies Molecular docking study molecular dynamics Molecular dynamics simulation MPro pharmacokinetic PLPro Protein repurposing Research RMSD RMSF SARS-CoV-2 selected spike spike glycoprotein spike glycoproteins Spike protein therapeutic therapeutic agent [DOI] 10.1016/j.micpath.2022.105615 PMC 바로가기 [Article Type] Article
Childhood, teenage and young adult cancer diagnosis during the first wave of the COVID-19 pandemic: a population-based observational cohort study in EnglandObservational Study Published on 2022-08-012022-10-04 Journal: Archives of Disease in Childhood [Category] 임상, [키워드] 95% CI adjusted Admission Admissions Cancer cancer diagnosis Central nervous system change childhood cohort study COVID-19 COVID-19 pandemic database decrease diagnose diagnosed diagnoses diagnostic England Epidemiology First wave Hospital admission identify incidence rate increase in initial intensive care lymphoma median Mortality Observational cohort study occurred outcome pandemic pathway primary care QResearch reduction in registry data setting significantly significantly more Specific time interval Treatment was used [DOI] 10.1136/archdischild-2021-322644 PMC 바로가기 [Article Type] Observational Study
Vaccination for herpes zoster in patients with solid tumors: a position paper on the behalf of the Associazione Italiana di Oncologia Medica (AIOM)고형 종양 환자의 대상포진 예방접종: 이탈리아 의학 종양학 협회(AIOM)를 대표한 입장문Review Published on 2022-08-012023-05-31 Journal: ESMO open [Category] Fulltext, 대상포진, 두창, 수두, 홍역, [키워드] Cancer herpes zoster Reactivation RZV Vaccine [DOI] 10.1016/j.esmoop.2022.100548 PMC 바로가기 [Article Type] Review
Humoral and cellular responses to mRNA-based COVID-19 booster vaccinations in patients with solid neoplasms under active treatmentArticle Published on 2022-08-012022-10-05 Journal: ESMO open [Category] 진단, 치료법, [키워드] acute respiratory syndrome anti-spike antibody antibodies baseline BNT162b2 booster booster dose booster vaccination breakthrough infections Cancer cancer patient Cancer patients Care cause CD19+ CD4+ cell counts Cellular immune response cellular immunity cellular response Chemotherapy coronavirus COVID-19 COVID-19 infection died disease dose Efficacy Endocrine evaluated excluded exclusion criteria Factor Factors high risk high-risk population hospital humoral Humoral immunity immune response Immunosuppression immunosuppressive Infection Messenger RNA Mild mRNA mRNA vaccine mRNA-1273 mRNA-based neoplasm neutralizing antibody older patients Other outcome overcome Patient positive reduced required Result severe coronavirus disease significant increase significantly increased significantly lower solid malignancy solid tumors T-cell Response treated Treatment vaccination Vaccine vaccine dose Vaccines were assessed [DOI] 10.1016/j.esmoop.2022.100587 [Article Type] Article
Conceptual Framework for Cancer Care During a Pandemic Incorporating Evidence From the COVID-19 PandemicArticle Published on 2022-08-012022-11-16 Journal: JCO Global Oncology [Category] SARS, 변종, [키워드] adverse impact Affect applicability applied Cancer cancer treatment Care changes in component consequence continuum COVID-19 COVID-19 pandemic Diagnosis effort framework Guidance Health Health Service health system health systems Impact increased risk Infection infection risk outcome pandemic Pandemics pathway Patients with cancer progression provide resource severity Spread Support variants [DOI] 10.1200/GO.22.00043 PMC 바로가기