Estimating global and regional disruptions to routine childhood vaccine coverage during the COVID-19 pandemic in 2020: a modelling study2020년 코로나19 팬데믹 기간 동안 정기적인 아동 백신 접종에 대한 전 세계 및 지역적 혼란 추정: 모델링 연구Articles Published on 2021-08-072022-10-30 Journal: Lancet (London, England) [Category] COVID-19, Fulltext, MERS, 백일해, 파상풍, [키워드] absence accelerate affected Analysis approach Asia burden childhood children Combination Coverage COVID-19 COVID-19 pandemic disease dose doses effort eligible estimate expected finding foundation funding Health Service Hierarchical highest Impact Latin America lowest Melinda Gate Middle East Oceania Outbreaks pandemic random reduce reduction reductions in regions Release remained representing resource risk routine SARS-CoV-2 transmission sub-Saharan Africa trajectory vaccination Vaccine vaccine dose widespread [DOI] 10.1016/S0140-6736(21)01337-4 PMC 바로가기 [Article Type] Articles
Hope level and associated factors among parents of retinoblastoma patients during COVID-19 pandemic: a cross-sectional studyResearch Article Published on 2021-08-062022-10-27 Journal: BMC Psychiatry [Category] COVID-19, [키워드] 2019 coronavirus disease Anxiety Cancer Characteristics children conducted COVID-19 COVID-19 pandemic cross-sectional cross-sectional survey demographic demographic data Depression Diagnosis disease Effect emotional Factor GAD-7 Generalized global public health Health status highest Hope Hope level IMPROVE incidence rate independent index Intervention investigated Linear regression analysis lowest measure Medicine medium mental health Monoculus Multiple Ninth ocular pandemic parent parental Patient Pediatric oncology Pneumonia positive Result retinoblastoma Risk factors School Shandong University Shanghai statistically significant Treatment university Variation [DOI] 10.1186/s12888-021-03401-0 PMC 바로가기 [Article Type] Research Article
Hope level and associated factors among parents of retinoblastoma patients during COVID-19 pandemic: a cross-sectional studyResearch Article Published on 2021-08-062022-10-27 Journal: BMC Psychiatry [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] 2019 coronavirus disease Anxiety Cancer Characteristics children conducted COVID-19 COVID-19 pandemic cross-sectional cross-sectional survey demographic demographic data Depression Diagnosis disease Effect emotional Factor GAD-7 Generalized global public health Health status highest Hope Hope level IMPROVE incidence rate independent index Intervention investigated Linear regression analysis lowest measure Medicine medium mental health Monoculus Multiple Ninth ocular pandemic parent parental Patient Pediatric oncology Pneumonia positive Result retinoblastoma Risk factors School Shandong University Shanghai statistically significant Treatment university Variation [DOI] 10.1186/s12888-021-03401-0 PMC 바로가기 [Article Type] Research Article
Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patientsNetosis 마커 및 습기의 진화는 중환자가 아픈 Covid-19 환자에서 예후 가치가 있습니다.Article Published on 2021-08-032022-08-31 Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 진단, 치료기술, [키워드] (cfDNA) Acute inflammation Cell cfDNA Clinical parameters controls coronavirus coronavirus disease coronavirus disease 19 correlated COVID-19 COVID-19 patient COVID-19 patients Critically ill damage DAMP decrease disease severities disease severity Disease-free survival DNA event Evolution Extracellular GAS6 ICU ICU admission immune Infection intensive care intensive care unit lead lowering lowest marker measure molecular pattern molecular patterns Mortality multi-organ dysfunction NETosis neutrophil neutrophil counts Neutrophil elastase Neutrophils Occurrence parameter parameters Patient patient survival plasma Prognostic value Respiratory failure Respiratory tract diseases scoring system Sepsis severe COVID-19 survival the patient tissue damage Ventilator-free days viral infection weakness [DOI] 10.1038/s41598-021-95209-x PMC 바로가기 [Article Type] Article
Von Willebrand factor and ADAMTS13 activity as clinical severity markers in patients with COVID-19COVID-19 환자의 임상 중증도 마커로서의 폰 빌레브란트 인자 및 ADAMTS13 활성Article Published on 2021-08-012022-09-11 Journal: Journal of Thrombosis and Thrombolysis [Category] MERS, SARS, 바이오마커, [키워드] ADAMTS13 age and gender Antigen clinical outcomes Clinical severity coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 outpatient COVID-19 outpatients COVID-19 patient COVID-19 patients D-dimer diagnosed disease severity Endothelial dysfunction endothelial injury enrolled evaluate fibrinogen healthy individual highest hypercoagulability ICU patient ICU Patients Imbalance increase increase in Inpatient Inpatients intensive care intensive care unit lead lowest marker mechanism Medical conditions Non-COVID-19 Patient patients with COVID-19 plasma predict Prospective Study prothrombotic state recruited reduction reduction in thrombotic thrombotic risk von Willebrand factor vWF were measured with COVID-19 [DOI] 10.1007/s11239-021-02457-9 PMC 바로가기 [Article Type] Article
Thyroid Hormone Profile and Its Prognostic Impact on the Coronavirus Disease 2019 in Korean Patients2019년 한국인 환자의 갑상선 호르몬 프로필과 코로나바이러스 질병에 대한 예후적 영향Observational Study Published on 2021-08-012022-09-11 Journal: Endocrinology and metabolism (Seoul, Korea) [Category] MERS, 바이오마커, 임상, [키워드] 95% confidence interval Admission analyzed association change clinical Clinical data clinical outcomes coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Critical disease death Decreased disease disease severity dysfunction euthyroid Euthyroid sick syndromes evaluate evaluated followed by hazard ratio highest hormone Hormones Impact intensive care intensive care unit admission Korean lowest marker mechanical ventilation middle Mortality outcome Patient patients patients with COVID-19 profile Prognosis prognostic reported serum sick significantly lower South Korea suppression suppression of thyroid function syndrome Thyroid thyroid dysfunction thyroid function thyroid hormone Thyroid hormones thyroid stimulating hormone thyrotoxicosis triiodothyronine Triiodothyronine. TSH [DOI] 10.3803/EnM.2021.1109 PMC 바로가기 [Article Type] Observational Study
Intravenous methylprednisolone with or without tocilizumab in patients with severe COVID-19 pneumonia requiring oxygen support: A prospective comparison산소 공급이 필요한 중증 COVID-19 폐렴 환자에서 토실리주맙을 포함하거나 포함하지 않는 정맥 내 메틸프레드니솔론: 전향적 비교Randomized Controlled Trial Published on 2021-08-012022-09-12 Journal: Journal of infection and public health [Category] SARS, 임상, 진단, [키워드] 1:1 Adding addition Administered administration Admission all-cause mortality Arm control arm control group controls coronavirus disease Course COVID-19 determine died disease severity Dubai electronic medical records exclusion criteria FIVE group highest Hospital stay ICU ICU admission IMPROVE Inclusion intensive care intravenous intravenous tocilizumab Invasive mechanical ventilation lowest marker Methylprednisolone Methylprednisolone therapy morbidity and mortality Mortality one patient outcome oxygen oxygen support Oxygen therapy Patient patients hospitalized patients treated Pneumonia Primary outcome randomization Randomized randomized controlled study rates of admission receive recruited reduce reduced retrospective SARS-CoV-2 severe COVID-19 Severe COVID-19 pneumonia severity significantly significantly lower single dose survival time Tocilizumab treated Treatment usual care Ventilation ventilator while [DOI] 10.1016/j.jiph.2021.06.003 PMC 바로가기 [Article Type] Randomized Controlled Trial
Association of Simulated COVID-19 Policy Responses for Social Restrictions and Lockdowns With Health-Adjusted Life-Years and Costs in Victoria, AustraliaResearch Published on 2021-07-302022-10-30 Journal: JAMA Health Forum [Category] COVID-19, SARS, [키워드] addition Aggressive approach benefit Brazil collected data conducted consequence COVID-19 COVID-19 pandemic death determine epidemiological epidemiological data Estimated Europe finding GDP Health health system highest hospitalizations Importance India infection rate interval lockdown lockdowns lowest measure median Model moderate New NMB objective occurred Older outcome overlap participant per day Perspective Point Policy Relevance response responses restriction Result SARS-COV-2 infection SARS-CoV-2 infections scaled up setting South Stage Taiwan United States Victoria was used Weighing while with COVID-19 [DOI] 10.1001/jamahealthforum.2021.1749 PMC 바로가기 [Article Type] Research
Combination Treatment With Remdesivir and Ivermectin Exerts Highly Synergistic and Potent Antiviral Activity Against Murine Coronavirus Infection렘데시비르와 이버멕틴의 병용 치료는 쥐 코로나바이러스 감염에 대해 높은 시너지 효과와 강력한 항바이러스 활성을 나타냅니다.Cellular and Infection Microbiology Published on 2021-07-302022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 치료제, [키워드] activity Against antiviral drug antiviral therapy Betacoronavirus Betacoronavirus genus both viruses Cell Chloroquine clinical clinical trial clinical trials Combination combination therapy combination treatment coronavirus COVID-19 COVID-19 pandemic cytokine level develop doxycycline drug drug therapy effective Efficacy evaluated exhibited Hepatitis highest IC50 IL-6 in vitro model in vivo experiment indicated infect Infection inhibitory investigated Ivermectin ivermectin treatment leukemia Live virus lowest Macrophage macrophages mechanism MHV mice monotherapy murine hepatitis virus potent RAW264.7 macrophage cells reduction Remdesivir Replication Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections selectivity index sequence identity significant reductions synergism synergistic tested the Betacoronavirus the disease therapy TNF-α Treatment Trial urgency viability Viral Viral RNA virus viruses [DOI] 10.3389/fcimb.2021.700502 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Analysis of the specificity of a COVID-19 antigen test in the Slovak mass testing program슬로바키아 대량 검사 프로그램에서 코로나19 항원 검사의 특이성 분석Research Article Published on 2021-07-292022-09-12 Journal: PLoS ONE [Category] MERS, 진단, [키워드] adjusted Antigen assumption calculate COVID-19 expected False positives knowledge lowest mass multiplicity PCR tests positive positive test result Prevalence Region Result SARS-CoV-2 SD Biosensor Slovakia specificity Standard Q tested [DOI] 10.1371/journal.pone.0255267 PMC 바로가기 [Article Type] Research Article