RCT

[키워드] (neutrophil 24 hour 24 hours allergic allergic reaction Antibody titre Arm ARMS automated blinded Blinding body temperature BSMMU Care checked Clinical improvement collaboration collected comparator computer Controlled Controlled trial convalescent plasma COVID-19 creatinine criteria CRP CT scan deaths defined diastolic discharge dissemination Donor donors dose dose response effective effective dose Efficacy Efficacy and safety element ELISA end point enrolled Evidence evidence of excluded expected FiO2 generate Health Organization hospital Hospital stay ICU identify in-hospital mortality inclusion criteria initial intervention arms Laboratory laboratory parameter Laboratory parameters Laboratory tests lactating women lung lymphocyte multi-arm multicentre neutralizing antibody neutrophil normality number objective open outcome Oxford oxygen oxygen saturations PaO2 paO2/fiO2 participant Participants Patient PCR assay performed plasma Plasma transfusion positive pregnant Primary outcome proportion protocol random number table randomised Randomized controlled trial RCT receive recorded recording recruit recruited recruitment reduction in required respiratory respiratory distress respiratory rate respiratory symptoms room air RT-PCR RT-PCR assay Sample size sample size calculation SARS-CoV-2 secondary outcome serum creatinine Serum ferritin Seven Severe case severe cases severe COVID-19 severe COVID-19 patient severe COVID-19 patients Severe patient severe patients Severe respiratory distress Sex SGOT SGPT SpO2 sputum standard care status Study protocol Support systolic the patient therapy These data titre transfusion Treatment Trial university University of Oxford ventilator website World Health Organization X-ray
[DOI] 10.1186/s13063-020-04734-z PMC 바로가기 [Article Type] Letter