Self-care strategies in response to nurses’ moral injury during COVID-19 pandemicOriginal Manuscripts Published on 2020-10-302022-10-31 Journal: Nursing Ethics [Category] Coronavirus, MERS, SARS, [키워드] adverse effect Affect affected alleviate Care COVID-19 COVID-19 pandemic deaths emotional events healthcare Healthcare professional healthcare worker help infecting Injury instances institution lack Moral distress Moral injury MOST numbers of patient Nurse Nurses occur offer pandemic Patient patients professionals Protective protocol protocols Psychological well-being recommendation resource resources respond self-care shifting Support therapy trauma [DOI] 10.1177/0969733020961825 PMC 바로가기 [Article Type] Original Manuscripts
A platform incorporating trimeric antigens into self-assembling nanoparticles reveals SARS-CoV-2-spike nanoparticles to elicit substantially higher neutralizing responses than spike aloneArticle Published on 2020-10-232022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] added alleviate Antigen antigenicity Cryoelectron microscopy described elicit expressed expression ferritin fused glycoprotein Helicobacter pylori immunogen increasingly mammalian murine neutralizing response neutralizing responses parainfluenza platform prefusion prefusion conformation respiratory syncytial virus reveal SARS-CoV-2 stimulate strong immune response trimer trimeric vaccination Vaccines viral antigens viral infection [DOI] 10.1038/s41598-020-74949-2 PMC 바로가기 [Article Type] Article
COVID-19 Pandemic and Death Anxiety in Security Forces in SpainArticle Published on 2020-10-232022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] absence alleviate Anxiety Armed Forces Burnout caused consequence coronavirus COVID-19 COVID-19 disease death death anxiety determine develop Effect emotional evidenced force Health IMPROVE individual Intervention Jackson logistic regressions occupational health pandemic participated Perspective police Predictive professional protection Psychological psychological treatment Quantitative questionnaire risk security Spain stability state state security forces the SARS-CoV-2 variable virus [DOI] 10.3390/ijerph17217760 PMC 바로가기 [Article Type] Article
Covidom, a Telesurveillance Solution for Home Monitoring Patients With COVID-19Viewpoint Published on 2020-10-222022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, SARS, [키워드] alleviate app Care Cluster coronavirus disease COVID-19 Critical fill out global pandemic greater Health Health status home home monitoring infected patient Infectious disease MONITOR monitoring Paris Patient patients with COVID-19 professional questionnaire rapid response Registered responses solution telesurveillance triggered Wuhan, China [DOI] 10.2196/20748 PMC 바로가기 [Article Type] Viewpoint
Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 proteaseHIV-1 프로테아제의 약물 내성 관련 돌연변이 중 양성 상위성의 우세Research Article Published on 2020-10-212022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] alleviate antiretroviral drug antiretroviral drugs Author capture clinic clinical observation clinical observations Clinical studies clinical study clinically Combination combinations compensatory mutations deep sequencing Deleterious deleterious effect deleterious effects drug drug resistance Effect epistasis Evolution fitness Genetic genetic interactions greatly reduce HIV HIV-1 Impact in vitro inhibitors Interaction interactions involved likelihood long term majority mechanism mutant Mutation mutations observation outcome overcome pandemic patients persistence positive Prophylaxis protease Protease inhibitor protease inhibitors reduce Replication resistance mutations reversal reversion selection experiments sequence Support T cells therapy Viral viral genome viral replication [DOI] 10.1371/journal.pgen.1009009 PMC 바로가기 [Article Type] Research Article
Covid-19 Quarantine: Impact of Lifestyle Behaviors Changes on Endothelial Function and Possible Protective Effect of Beetroot JuiceNutrition Published on 2020-10-212022-10-31 Journal: Frontiers in Nutrition [Category] COVID-19, [키워드] alcohol alleviate Beetroot Behavior boredom cardiovascular disease Cardiovascular health change coronavirus COVID-19 COVID-19 outbreak CVD dietary nitrate Effect effective Endothelial dysfunction endothelial function exacerbated function hypertensive Impact IMPROVE individuals Juice Metabolic disorders morbidity and mortality Nitrate nitric oxide Physical inactivity Prevent progression reducing Risk factors smoking social distancing Stress Transmission Vascular endothelium vascular health [DOI] 10.3389/fnut.2020.582210 PMC 바로가기 [Article Type] Nutrition
Bioinspired DNase‐I‐Coated Melanin‐Like Nanospheres for Modulation of Infection‐Associated NETosis DysregulationFull Paper Published on 2020-10-202022-10-28 Journal: Advanced Science [Category] COVID-19, [키워드] Activation acute respiratory distress acute respiratory syndrome alleviate Antiviral treatment ARDS attenuate Bioinspiration caused circulation coronavirus coronavirus disease COVID‐19 COVID‐19 Cytokine storms Diseases DNase‐I dysregulation extracellular DNA Factor glycol illness Inflammation mechanism mitigate modulate Mortality Nanospheres NET NETosis NETs neutrophil count Neutrophil extracellular trap outbreak Pathogenesis plasma plasma membrane rupture Prevent programmed cell death progression promote recombinant reduce reported SARS‐CoV‐2 SARS‐CoV‐2 infection Sepsis sepsis patients syndrome systemic inflammation the disease Treatment Vaccine [DOI] 10.1002/advs.202001940 PMC 바로가기 [Article Type] Full Paper
Kinase inhibition in autoimmunity and inflammation Reviews Published on 2020-10-192022-10-05 Journal: Nature Reviews Drug Discovery [Category] 바이오마커, 치료제, [키워드] alleviate Autoimmune Autoimmunity BTK clinically dysregulated Effect Efficacy Inflammation Inflammatory diseases Inflammatory mediators inflammatory pathways inhibitor irak4 kinase Kinase inhibitor medical need offer regulate review SYK Therapeutic approach tissue Treatment [DOI] 10.1038/s41573-020-0082-8 [Article Type] Reviews
COVID-19 Outbreak: Pathogenesis, Current Therapies, and Potentials for Future ManagementPharmacology Published on 2020-10-162022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] acute respiratory syndrome alleviate alternative method antiviral treatments Candidates characterized coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus-2 CoV COVID-19 current effective Epidemiology etiology Future inhibit life-threatening MERS-CoV Middle East Middle East respiratory syndrome Coronavirus Novel coronavirus pathogenesis of COVID-19 Potential public health Replication respiratory syndrome coronavirus SARS-CoV SARS-CoV2 severe acute respiratory syndrome coronavirus-2 specific treatment spread of COVID-19 Symptom therapeutic intervention therapeutic interventions threat Transmission Treatment virus WHO World Health Organization Wuhan, China [DOI] 10.3389/fphar.2020.563478 PMC 바로가기 [Article Type] Pharmacology
Clinical characteristics and prognostic factors of COVID-19 patients progression to severe: a retrospective, observational studyResearch Paper Published on 2020-10-152022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, [키워드] Admission alleviate arthralgia C-reactive protein Characteristics clinical Clinical characteristics co-morbidities Coronary heart disease coronavirus disease correlated cough COVID-19 COVID-19 patient diabete distribution enrolled fatigue Fever help hospital identify Mild moderate mortality rate myalgia nomogram operator outbreak Patient Prognostic factor Prognostic factors progressed progression Regression model retrospective risk factor severe COVID-19 severity of COVID-19 symptomatic Symptoms temperature [DOI] 10.18632/aging.103931 PMC 바로가기 [Article Type] Research Paper