Development of a Novel, Genome Subtraction-Derived, SARS-CoV-2-Specific COVID-19-nsp2 Real-Time RT-PCR Assay and Its Evaluation Using Clinical SpecimensArticle Published on 2020-04-082022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] affected amplify clinical clinical evaluation Clinical management Concordance confirmed case coronavirus coronavirus genome country COVID-19 COVID-19-nsp2 assay cycle threshold deaths development epidemiological genome subtraction GolayMetaMiner limit of detection novel Novel coronavirus infection NSP2 nucleotide pandemic real-time RT-PCR Region reproducibility respiratory viruses RT-PCR SARS-CoV-2 sensitivity specificity specimen TCID the SARS-CoV-2 genome [DOI] 10.3390/ijms21072574 PMC 바로가기 [Article Type] Article
Lower respiratory tract infection in the community: associations between viral aetiology and illness courseOriginal Article Published on 2020-03-312022-11-01 Journal: Clinical microbiology and infection : the official [Category] Coronavirus, [키워드] 95% CI 95% confidence interval adjusted hazard ratio aetiology AhR Analysis association baseline Community comparable coronavirus cough Course CoV cycle threshold decrease Disease burden European group healthy Infection Influenza Influenza virus interquartile range Lower Lower respiratory tract lower respiratory tract infection métapneumovirus objective Patient patients PCR polymerase chain positive presenting primary care Primary Healthcare public health recruited respiratory syncytial virus respiratory tract infection respiratory virus respiratory viruses Result rhinovirus RSV RSV infection scored severe symptom significantly higher subsequent Symptom symptom duration symptom resolution symptom severity tested the median time Viral load viral respiratory virus was performed were assessed [DOI] 10.1016/j.cmi.2020.03.023 PMC 바로가기 [Article Type] Original Article
In vitro antiviral activity of fifteen plant extracts against avian infectious bronchitis virusResearch Article Published on 2019-05-292022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] antiviral activity Avian infectious bronchitis bronchitis Concentration cycle threshold cytopathogenic effect decrease Delta Dilution disease effective Efficacy Extract genotypes IBV Infection Infectious Bronchitis Virus Infectious disease limit log Mutation PCR plant plant extracts plants reduction Result RNA selected serotype significantly TCID tested Treatment virus virus plaque [DOI] 10.1186/s12917-019-1925-6 PMC 바로가기 [Article Type] Research Article
Pneumococcal pneumonia prevalence among adults with severe acute respiratory illness in Thailand – comparison of Bayesian latent class modeling and conventional analysis태국에서 중증 급성 호흡기 질환을 앓고 있는 성인에서 폐렴구균 폐렴 유병률 - 베이지안 잠재 클래스 모델링과 전통적 분석의 비교Research Article Published on 2019-05-152024-07-31 Journal: BMC Infectious Diseases [Category] 폐렴구균 감염증, [키워드] Bayesian latent class cycle threshold Pneumococcal density Pneumococcal pneumonia Pneumonia etiology Real-time polymerase chain reaction test Urine antigen test [DOI] 10.1186/s12879-019-4067-3 PMC 바로가기 [Article Type] Research Article
Association of Higher MERS-CoV Virus Load with Severe Disease and Death, Saudi Arabia, 2014Expedited Published on 2015-11-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS, [키워드] Admission Affect age cause clinical outcomes Clinical severity cycle threshold death decrease determine died E gene evaluated intensive care load median MERS-CoV Middle East Middle East respiratory syndrome Coronavirus modulation multivariable nasopharyngeal specimen outcome Patient patients positive Regression analyses respiratory syndrome coronavirus Result reverse transcription PCR risk factor Saudi Arabia significantly lower survivor tested the median therapeutic agent upstream virus virus load viruses zoonoses [DOI] 10.3201/eid2111.150764 PMC 바로가기 [Article Type] Expedited
Effect of Porcine Epidemic Diarrhea Virus Infectious Doses on Infection Outcomes in Naïve Conventional Neonatal and Weaned PigsResearch Article Published on 2015-10-062022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] Antibody Response caused cell culture medium Clinical signs condition Conventional cycle threshold determine Effect epidemic diarrhea group Histopathology immunohistochemistry Infection infectious dose infectious titer information inoculated medium naïve Neonatal Neonate observation PCR PEDV pig polymerase chain significantly lower Spread TCID the United State virulent virus [DOI] 10.1371/journal.pone.0139266 PMC 바로가기 [Article Type] Research Article
Anti-influenza A virus activity of uridine derivatives of 2-deoxy sugarsArticle Published on 2013-10-012023-06-24 Journal: Antiviral Research [Category] 신종인플루엔자, [키워드] CC(50) classical swine fever virus concentration of the compound required to reduce cell viability by 50% concentration of the compound required to reduce virus plaque formation by 50% CPE CSFV CT cycle threshold Cytopathic effect Endoplasmic reticulum ER Glycoproteins Glycosylation inhibition HA hemagglutinin IC(50) influenza A virus l-1-tosylamide-2-phenylethyl chloromethyl ketone Madin–Darby canine kidney cells MDCK MOI multiplicity of infection NA neuraminidase S.D. selectivity index Sf9 SI Spodoptera frugiperda insect cell line standard deviations. TPCK Tunicamycin derivatives [DOI] 10.1016/j.antiviral.2013.07.014