Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 BindingResource Published on 2020-09-032022-10-31 Journal: Cell [Category] COVID-19, [키워드] ACE2 ACE2 binding ACE2 receptor Affect Amino acid Analysis Antibody therapeutics COVID-19 dataset deep deep mutational scanning Deleterious determine dominant Effect ENhance Evidence expression facilitate folded protein functional annotation host range identify interface residue isolate isolates MOST Mutation Neutralizing antibodies pandemic RBD RBD expression Receptor binding domain Receptor-binding domain Region SARS-CoV-2 SARS-CoV-2 pandemic SARS-related coronaviruses scanning selected spike glycoprotein Spike protein Substitution Surveillance target the RBD the SARS-CoV-2 Vaccine Vaccine design virus [DOI] 10.1016/j.cell.2020.08.012 PMC 바로가기 [Article Type] Resource
Big Data, Natural Language Processing, and Deep Learning to Detect and Characterize Illicit COVID-19 Product Sales: Infoveillance Study on Twitter and InstagramOriginal Paper Published on 2020-08-252022-10-31 Journal: JMIR Public Health and Surveillance [Category] COVID-19, MERS, [키워드] Accompanying approaches approved Care Characteristics collected Combination conducted Contact coronavirus coronavirus disease COVID-19 COVID-19 testing cybercrime Data analysis deep deep learning Enabling filtered fraud Health help identify Infectious disease infodemic infodemiology infoveillance initial Instagram involved language learning natural objective offered Other pandemic pandemic progresse platform Prevent processing product programming proliferation public health Regulatory Authorities Result social media social media platform Stage Surveillance Treatment Volume [DOI] 10.2196/20794 PMC 바로가기 [Article Type] Original Paper
Weakly-Supervised Network for Detection of COVID-19 in Chest CT ScansComputational and Artificial Intelligence Published on 2020-08-212022-10-30 Journal: Ieee Access [Category] COVID-19, [키워드] Analysis applied approach Attention block Chest Computed tomography conducted COVID-19 COVID-19 diagnosis data sets datasets deep deep learning detection effective Effectiveness Efficiency enhancement experimental results Features Final generate IMPROVE Long LSTM lung network pandemic Precision Segmentation term Volume weakly-supervised learning [DOI] 10.1109/ACCESS.2020.3018498 PMC 바로가기 [Article Type] Computational and Artificial Intelligence
Dynamics and Development of the COVID-19 Epidemic in the United States: A Compartmental Model Enhanced With Deep Learning TechniquesOriginal Paper Published on 2020-08-212022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, [키워드] basic reproduction number Characteristics compartmental model Compartmental models confirmed case coronavirus disease COVID-19 COVID-19 epidemic cross current deep deep learning development Dynamics effective Effectiveness enhanced Epidemic Epidemiology estimation learning less methodology Model modeling objective parameter predict predicted reduced Result simulate suppressed technique the epidemic Transmission transmission parameter transmission parameters virus [DOI] 10.2196/21173 PMC 바로가기 [Article Type] Original Paper
Spontaneous Retroperitoneal Bleed Coincided With Massive Acute Deep Vein Thrombosis as Initial Presentation of COVID-19Internal Medicine Published on 2020-08-152022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute deep vein thrombosis Acute myocardial infarction acute respiratory syndrome Affect anticoagulant therapy anticoagulation bilateral pneumonia bleeding cause caused clinician Coagulopathy compartment syndrome Complication complications of COVID-19 coronavirus coronavirus disease COVID-19 CRRT deep DVT ECMO extracorporeal membrane oxygenation global pandemic Health Hemorrhagic hypercoagulable Hypercoagulable state hypoxemic Ischemia knowledge less limb massive Novel coronavirus organ systems Patient patient with COVID-19 presentation renal replacement therapy reported Respiratory failure resulting Retroperitoneal retroperitoneal bleeding risk SARS-CoV-2 SARS-COV-2 infection selected Spontaneous stroke syndrome the disease therapy thrombosis Thrombotic complications Thrombotic events Vein Venous Thromboembolism [DOI] 10.7759/cureus.9772 PMC 바로가기 [Article Type] Internal Medicine
Deep learning‐based survival analysis for brain metastasis patients with the national cancer databaseRadiation Oncology Physics Published on 2020-08-132022-10-30 Journal: Journal of Applied Clinical Medical Physics [Category] Coronavirus, MERS, SARS, [키워드] age Analysis assessment Brain brain metastasis breast cancer patient Cancer classical clinical setting clinically Concordance covariate Cox proportional hazard CPU database deep deep learning hormone receptor information machine learning Metastasis National Patient patient survival physician Predictive previous study Prognosis prognostic indicator provided random Result risk RPA shown statistically significant difference stereotactic radiosurgery survival Test the mean treatment regimen was used were used [DOI] 10.1002/acm2.12995 PMC 바로가기 [Article Type] Radiation Oncology Physics
Evaluation of the Ion AmpliSeq SARS-CoV-2 Research Panel by Massive Parallel SequencingArticle Published on 2020-08-122022-10-31 Journal: Genes [Category] COVID-19, MERS, [키워드] amplicons amplification amplified Analysis Coverage COVID-19 deep develop diagnostic procedures Effectiveness evaluate feature Genetic geographical area Ion isolate knowledge manufacturer’s instructions massive massively parallel sequencing MPS Nasopharyngeal swab overlapping pandemic Panel patients PCR PCR cycle primer processed promote protocol Public health interventions reverse transcription RT-PCR SARS-CoV-2 SARS-CoV-2 sequence data Sequencing sequencing coverage target region target regions Therapeutic strategies Vaccines viral genome viral isolate Viral RNA were used whole genome [DOI] 10.3390/genes11080929 PMC 바로가기 [Article Type] Article
Identifying COVID19 from Chest CT Images: A Deep Convolutional Neural Networks Based ApproachResearch Article Published on 2020-08-112022-10-31 Journal: Journal of Healthcare Engineering [Category] Coronavirus, MERS, SARS, [키워드] applicability approach AUROC average Chest CT images CNN COVID19 deep diagnostic Experimental result Final healthcare identifying Infectious disease limitation network Neural observation Performance metrics RT-PCR utility [DOI] 10.1155/2020/8843664 PMC 바로가기 [Article Type] Research Article
Development and Validation of a Deep Learning-Based Model Using Computed Tomography Imaging for Predicting Disease Severity of Coronavirus Disease 2019Bioengineering and Biotechnology Published on 2020-07-312022-10-31 Journal: Frontiers in Bioengineering and Biotechnology [Category] COVID-19, [키워드] 105 patient 95% confidence interval Accuracy Admission assigned AUC characteristic Clinical treatment collected Computed tomography Confusion Coronavirus disease 2019 COVID-19 COVID-19 patient deep deep learning develop development Disease progression disease severity evaluated fatality globe help hospital imaging Infection Intervention material Model Multiple instance learning objective Patient predict prevent disease progression reduce mortality Result risk severe disease severely ill patient subgroup analysis subgroups Symptom test dataset training data university validation with COVID-19 [DOI] 10.3389/fbioe.2020.00898 PMC 바로가기 [Article Type] Bioengineering and Biotechnology
Deep transfer learning artificial intelligence accurately stages COVID-19 lung disease severity on portable chest radiographsResearch Article Published on 2020-07-282022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] Analysis analyzed approach average Chest CNN correlated correlation coefficient COVID-19 COVID-19 patient CXR datasets deep disease severity Infection information lung Lung disease Lung infection management mean absolute error performed predict R 2 radiologist resource risk scored severity severity scores Stage Standard deviation survival transfer Treatment response was used yielding [DOI] 10.1371/journal.pone.0236621 PMC 바로가기 [Article Type] Research Article