Heterogeneous genetic diversity pattern in Plasmodium vivax genes encoding merozoite surface proteins (MSP) -7E, −7F and -7L플라스모디움 비박스 유전자에서 메로조이트 표면 단백질(MSP) -7E, -7F 및 -7L을 암호화하는 이질적인 유전적 다양성 패턴Research Published on 2014-12-132024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] genetic diversity msp-7 natural selection Plasmodium vivax selective sweep [DOI] 10.1186/1475-2875-13-495 PMC 바로가기 [Article Type] Research
Extensive Copy-Number Variation of Young Genes across Stickleback Populations스틱백 개체군에 걸친 젊은 유전자의 광범위한 복사 수 변이Research Article Published on 2014-12-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adaptive Analysis candidate Candidates category CNV CNV gene CNV genes CNVs Comparative genomics complexity copy-number variation copy-number variations disparate distribution duplicate gene Duplicate genes duplication duplications eco-genomic model ecological Effect elevated evaluate Evolution Extensive fixed Frequency function functional Genes Genetic genetic diversity Genome highlight identify individual Innovation interactions joint lineage-specific gene lineage-specific genes Local locus low frequencies molecular natural populations occur over Population population genomics population level populations prevalent producing selective pressure selective pressures Stage structural polymorphism subset teleost genome teleost genomes three-spined stickleback three-spined sticklebacks Variation whole genome sequence [DOI] 10.1371/journal.pgen.1004830 PMC 바로가기 [Article Type] Research Article
Individual genetic diversity and probability of infection by avian malaria parasites in blue tits (Cyanistes caeruleus)article Published on 2014-11-302024-09-01 Journal: Journal of Evolutionary Biology [Category] 말라리아, [키워드] Avian malaria disease genetic diversity heterozygosity-fitness correlations Plasmodium [Article Type] article
Genetic polymorphism and amino acid sequence variation in Plasmodium falciparum GLURP R2 repeat region in Assam, India, at an interval of five years인도 아삼에서 5년 간격으로 플라스모디움 팔시파룸 GLURP R2 반복 영역의 유전적 다형성과 아미노산 서열 변이Research Published on 2014-11-212024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Amino acid genetic diversity Glurp malaria Plasmodium falciparum Repeated sequence [DOI] 10.1186/1475-2875-13-450 PMC 바로가기 [Article Type] Research
Prevalence and Genetic Diversity Analysis of Human Coronavirus OC43 among Adult Patients with Acute Respiratory Infections in Beijing, 2012Research Article Published on 2014-07-022022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] Acute respiratory infection addition Amino acid Analysis ARI assays Beijing circulating Cluster coding region collected Consensus described determine Diversity epidemiological Epidemiology Evidence genetic diversity HCoV-OC43 human coronavirus human coronavirus OC43 Infection N gene nasopharyngeal swab sample OC43 occurred Partial Patient patients patients with ARI Phylogenetic Phylogenetic analysis polymerase chain Prevalence profile respiratory reverse transcription RT-PCR sequence sequenced strain the epidemic the patient unique [DOI] 10.1371/journal.pone.0100781 PMC 바로가기 [Article Type] Research Article
Recombination Accelerates Adaptation on a Large-Scale Empirical Fitness Landscape in HIV-1재조합은 HIV-1의 대규모 경험적 피트니스 환경에 대한 적응을 가속화합니다Research Article Published on 2014-06-262022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accelerate adaptation data set dependent on Effect empirical evidence Evidence Evolution evolutionary dynamics examined facilitate fitness Genetic genetic diversity genetic material highlight HIV HIV-1 in vitro increase Increases increases in Interaction landscape mechanism Mutation mutation rate Mutation rates organism parameter Population Population size population sizes populations question raise Recombination recombination rate recombination rates sexual reproduction significantly Strains theory [DOI] 10.1371/journal.pgen.1004439 PMC 바로가기 [Article Type] Research Article
Introgression from Domestic Goat Generated Variation at the Major Histocompatibility Complex of Alpine Ibex알파인 아이벡스의 주요 조직 적합성 복합체에서 국내 염소 생성 변이로부터의 이입Research Article Published on 2014-06-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] adaptive allele alleles Alpine ibex balancing selection breed carried chromosomal region Clustering coding coding regions Defense Evidence functional gene genetic diversity Genetic polymorphism genetic variability Genetic variation genomes goat Haplotype haplotypes heterozygosity histocompatibility histocompatibility complex homozygous Ibex identify immune system individual introgression investigated involved loci locus Major major histocompatibility complex mechanism MHC non-coding region pathogen Pathogens polymorphism populations provide Research restored sequence sequenced Sequencing signature SNP SNP allele SNP alleles species Support susceptible thought two allele Two alleles Variation [DOI] 10.1371/journal.pgen.1004438 PMC 바로가기 [Article Type] Research Article
Chloroquine efficacy studies confirm drug susceptibility of Plasmodium vivax in Chennai, India클로로퀸 효능 연구는 인도 첸나이에서 플라스모디움 비박스의 약물 감수성을 확인합니다.Research Published on 2014-03-312024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Chennai Chloroquine genetic diversity in vitro in vivo Plasmodium vivax [DOI] 10.1186/1475-2875-13-129 PMC 바로가기 [Article Type] Research
Limited genetic diversity and purifying selection in Iranian Plasmodium falciparum Generative Cell Specific 1 (PfGCS1), a potential target for transmission-blocking vaccinearticle Published on 2014-03-312024-09-01 Journal: Infection, Genetics and Evolution [Category] 말라리아, [키워드] Generative cell specific 1 (GCS1) genetic diversity Plasmodium falciparum transmission-blocking vaccine [Article Type] article
Temperate Phages Acquire DNA from Defective Prophages by Relaxed Homologous Recombination: The Role of Rad52-Like Recombinases온대 파지는 이완된 상동 재조합에 의해 결함 있는 프로파지로부터 DNA를 획득한다: Rad52-유사 재조합효소의 역할Research Article Published on 2014-03-062022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] acquisition addressed Bacteria Bacterial bacterial virus bacterial viruses bacteriophage bacteriophages Bioinformatics analysis biosphere catalyzed comparison complementary contribute defective prophages dependent on Divergence DNA dormant dormant state E. coli Efficiency element Escherichia coli Evidence evidence of Evolution exchange functions gene exchange gene exchanges gene transfer Genetic genetic determinant genetic determinants genetic diversity genetic exchanges Genome genomes genomic Homologous recombination homologous recombination enzymes horizontal gene Horizontal gene transfer Hypothesis in vivo Infection lambdoid phage lambdoid phages majority mechanism molecular mechanisms mosaicism no evidence of phage phage encoded recombinase phage encoded recombinases phage gene phage genome phage λ phages phenotype promote prophage prophages Rad52 RecA REcombinase recombinases Recombination replicate role sequence sequence homology sequences subject Temperate bacteriophage Temperate bacteriophages temperate phage temperate phages transfer virulence virulent virulent phages viruses vivo assays [DOI] 10.1371/journal.pgen.1004181 PMC 바로가기 [Article Type] Research Article