Diabetic retinopathy is independently associated with increased risk of intubation: A single centre cohort study of patients with diabetes hospitalised with COVID-19Clinical Trial Published on 2021-01-012022-10-05 Journal: Diabetes research and clinical practice [Category] SARS, 임상, [키워드] association cohort study COVID-19 Diabetic Diabetic retinopathy Endothelial dysfunction explain hospitalised increased risk intubation mechanism Microvascular disease Patient patients with diabete required retinopathy severe COVID-19 with COVID-19 [DOI] 10.1016/j.diabres.2020.108529 PMC 바로가기 [Article Type] Clinical Trial
Database of epidemic trends and control measures during the first wave of COVID-19 in mainland ChinaArticle Published on 2021-01-012022-10-29 Journal: International Journal of Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] Analysis applied available data case fatality ratio China conducted Contact Contact tracing Control measure coronavirus disease COVID-19 COVID-19 epidemic Critical database declined distribution Epidemic Epidemics First wave FIVE greater Health authority hospitalised information Intervention introduced Local lockdown measure media objective proportion quarantine reported Research resource response Result School severity Spread subsequent switching the epidemic These data Transmission Travel [DOI] 10.1016/j.ijid.2020.10.075 PMC 바로가기 [Article Type] Article
The role of CPAP as a potential bridge to invasive ventilation and as a ceiling-of-care for patients hospitalized with Covid-19—An observational studyCPAP가 침습적 환기에 대한 잠재적 다리 역할과 Covid-19로 입원한 환자를 위한 치료 천장으로서의 역할 - 관찰 연구Clinical Trial Published on 2020-12-312022-08-13 Journal: PLoS ONE [Category] MERS, SARS, 임상, [키워드] 24 hour 24 hours Admission Analysis association benefit Care ceiling collected conducted Continuous CPAP death defined Evidence examined Face mask finding foundation hospitalised hospitalised COVID-19 patients hypoxaemia IMV indication initial intubation Invasive mechanical ventilation invasive ventilation limitation mode Mortality NHS novel occurred offer oxygen Oxygen therapy Patient patients patients died patients hospitalized positive airway pressure receiving required respiratory Respiratory Support retrospective cohort Sample separated standard oxygen therapy strength survival Swab therapeutic Trial Trust Ventilation were excluded [DOI] 10.1371/journal.pone.0244857 PMC 바로가기 [Article Type] Clinical Trial
Randomised placebo-controlled multicentre effectiveness trial of adjunct betamethasone therapy in hospitalised children with community-acquired pneumonia: a trial protocol for the KIDS-STEP trial지역사회획득 폐렴으로 입원한 소아에 대한 보조 베타메타손 요법의 무작위 위약 대조 다기관 유효성 시험: KIDS-STEP 시험을 위한 시험 프로토콜Article Published on 2020-12-292022-09-11 Journal: BMJ Open [Category] SARS, 임상, [키워드] 48 hour 48 hours ACCIDENT & addition Adults Ambulatory care analysed and ambulatory care antibiotic approved average betamethasone Caregivers cause children clinically community-acquired pneumonia Complication double-blind E Each Effectiveness Emergency Departments emergency medicine enrolled Ethics Evidence healthcare hospital Hospital stay hospitalisation hospitalised immunisation include increase in Infectious disease inferiority Informed consent International lack margin matching placebo media multicentre National non-inferiority observational studies outcome paediatric A& paediatric infectious disease & paediatric thoracic medicine. participant Patient peer-reviewed Placebo placebo-controlled Pneumonia power power of 80% press proportion randomisation randomised readmission registration number regulatory authority Sample size secondary Secondary outcomes social media stability Standard of care steroid steroid treatment Steroids Swissmedic Switzerland therapy Thoracic Treatment Trial trial protocol use of steroids [DOI] 10.1136/bmjopen-2020-041937 PMC 바로가기 [Article Type] Article
Intravenous methylprednisolone pulse as a treatment for hospitalised severe COVID-19 patients: results from a randomised controlled clinical trial입원한 중증 COVID-19 환자를 위한 치료제로서의 정맥내 메틸프레드니솔론 펄스: 무작위 대조 임상 시험의 결과Randomized Controlled Trial Published on 2020-12-242022-08-13 Journal: The European Respiratory Journal [Category] 임상, [키워드] 1:1 95% CI administration Analysis attending physician Block randomisation Clinical improvement clinical trial conducted Controlled clinical trial Corticosteroid Corticosteroids COVID-19 COVID-19 patient COVID-19 patients death demonstrated eligible patient hazard ratio hospitalised hospitalised patient Immunosuppressive treatment Inflammation Inflammatory marker inflammatory markers initiation of treatment intention-to-treat Intravenous injection Iran ITT log-rank test Methylprednisolone methylprednisolone group mortality rate oxygen oxygen saturation Patient pulmonary involvement pulse randomisation randomised controlled Randomly receive reduce respiratory Respiratory system Result safety analysis severe adverse event severe adverse events severe COVID-19 severe COVID-19 patient significantly increased significantly lower single-blind standard care standard care group suggested survival survival time therapeutic therapeutic agent Treatment Two patient two patients was done were excluded [DOI] 10.1183/13993003.02808-2020 PMC 바로가기 [Article Type] Randomized Controlled Trial
Systematic evaluation and external validation of 22 prognostic models among hospitalised adults with COVID-19: an observational cohort studyCOVID-19로 입원한 성인의 22개 예후 모델에 대한 체계적인 평가 및 외부 검증: 관찰 코호트 연구Observational Study Published on 2020-12-242022-09-06 Journal: The European Respiratory Journal [Category] Communicable Disease, Fulltext, MERS, 임상, [키워드] 95% CI Admission age analyses AUROC benefit calibration candidate models characteristic Clinical deterioration coronavirus disease Coronavirus disease 2019 COVID-19 demonstrated description Deterioration diagnosis of COVID-19 discrimination Endpoint endpoints evaluated external validation Final final diagnosis hospital hospitalised implementation In-hospital in-hospital mortality Mortality NEWS2 Observational cohort study offered outcome oxygen oxygen saturation participant Patient patient age patients predictor predictors prognostic prognostic model Prognostic models receiver operating characteristic reconstructed room air Stratification systematic review tested threshold univariable widespread with COVID-19 [DOI] 10.1183/13993003.03498-2020 PMC 바로가기 [Article Type] Observational Study
Adverse drug reactions in SARS-CoV-2 hospitalised patients: a case-series with a focus on drug–drug interactionsObservational Study Published on 2020-12-232022-10-04 Journal: Internal and Emergency Medicine [Category] MERS, SARS, 임상, [키워드] addition ADR ADRS Adverse drug reaction Adverse drug reactions age Caucasian patient Characteristics Clinical characteristics collected Comorbidities COVID-19 COVID-19 patient disorders drug–drug interaction Drug–drug interactions drugs effective evaluated Evidence Florence hospitalised hospitalised patient Hospitalised patients identify Interaction interactions internal medicine Italy less majority males medications outcome patients pharmacokinetic pharmacological pharmacovigilance preferred term Psychiatric QT interval QT prolongation reported resolved risk SARS-CoV-2 study period supplementary material treatments for COVID-19 unit university [DOI] 10.1007/s11739-020-02586-8 PMC 바로가기 [Article Type] Observational Study
Prevalence of malnutrition in coronavirus disease 19: the NUTRICOV studyObservational Study Published on 2020-12-212022-10-04 Journal: The British Journal of Nutrition [Category] Fulltext, MERS, SARS, 임상, [키워드] 95 % CI Admission Analysis approach BMI Care chronic Cohort coronavirus disease COVID-19 criteria diagnosed Diagnosis died dyslipidaemia enrolled Enteral European European Society of Parenteral and Enteral Nutrition evaluate exhibited glomerular filtration rate hospitalised initiative Inpatient intensive care intensive care units leadership logistic regression model Malnutrition management Multivariate analysis nutrition nutritional support Occurrence Parenteral Patient patients Prevalence prospective observational cohort recent reduction Society Treatment two group two groups Univariate analysis [DOI] 10.1017/S0007114520005127 PMC 바로가기 [Article Type] Observational Study
The first wave of the COVID-19 pandemic in Spain: characterisation of cases and risk factors for severe outcomes, as at 27 April 2020Surveillance Published on 2020-12-172022-10-31 Journal: Eurosurveillance [Category] COVID-19, MERS, SARS, [키워드] 95% confidence interval Admission admitted to ICU affected cardiovascular category characterisation Characteristics chronic renal disease condition coronavirus disease COVID-19 COVID-19 case COVID-19 cases COVID-19 pandemic death declining died disease disease severity enhanced Epidemic females First wave HCWs healthcare worker higher odd higher risk highest hospitalisation hospitalised ICU identify intensive care lockdown measure multivariable National Odds ratio outcome outcomes pandemic PCR-confirmed peaked Pneumonia proportion renal reported Result risk factor Risk factors SARS-CoV-2 severity Spain Spread subgroup Surveillance surveillance data underlying disease underlying diseases were used [DOI] 10.2807/1560-7917.ES.2020.25.50.2001431 PMC 바로가기 [Article Type] Surveillance
High-Dose Cholecalciferol Booster Therapy is Associated with a Reduced Risk of Mortality in Patients with COVID-19: A Cross-Sectional Multi-Centre Observational Study고용량 콜레칼시페롤 부스터 요법은 COVID-19 환자의 사망률 감소와 관련이 있습니다: 횡단면 다중 센터 관찰 연구Clinical Trial Published on 2020-12-112022-08-13 Journal: Nutrients [Category] MERS, SARS, 임상, [키워드] 2019 novel coronavirus 2019 novel coronavirus disease 25-hydroxyvitamin D 95% CI affected appear baseline carried cholecalciferol cholecalciferol booster therapy cholecalciferol therapy clinical trial Cohort collected confounder coronavirus disease COVID-19 COVID-19 mortality determine disease Efficacy hospitalised in-patient Logistic regression Mortality Novel coronavirus novel coronavirus 2019 novel coronavirus disease observational study participant Patient patients pharmacological management population studies predictor predictors public health recruited reduced risk replicated SARS-CoV-2 serum serum 25-hydroxyvitamin D therapeutic option therapeutic options Treatment UK hospitals validation cohort Vitamin D Vitamin D status vitamin D treatment was used with COVID-19 worldwide pandemic [DOI] 10.3390/nu12123799 PMC 바로가기 [Article Type] Clinical Trial