Evaluation of the Liberty16 Mobile Real Time PCR Device for Use With the SalivaDirect Assay for SARS-CoV-2 TestingSARS-CoV-2 테스트를 위한 SalivaDirect 분석과 함께 사용하기 위한 Liberty16 모바일 실시간 PCR 장치 평가Cellular and Infection Microbiology Published on 2022-01-182022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 치료기술, [키워드] approach benefit Community comparable COVID-19 COVID-19 pandemic Device diagnostics gold gold standard greater implementation limit of detection Mobile PCR performed protocol resources respiratory respiratory diseases RNA copies RT-qPCR Saliva saliva samples SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA SARS-CoV-2 testing sensitivity Testing time while [DOI] 10.3389/fcimb.2021.808773 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
An ultrasensitive molecularly imprinted polymer-based electrochemical sensor for the determination of SARS-CoV-2-RBD by using macroporous gold screen-printed electrode거대 다공성 금 스크린 인쇄 전극을 사용한 SARS-CoV-2-RBD 측정을 위한 초고감도 분자 각인 고분자 기반 전기화학 센서Article Published on 2022-01-152022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alkaline ATR Concentration coronavirus Electrochemical sensor electrode electron microscope electron transfer Ethanol exhibited ferrocyanide gold limit of detection Macroporous gold screen-printed electrode Microscope MIP Molecularly imprinted polymer Polymer polymer matrix Receptor-binding domain Saliva SARS-CoV-2-RBD scanning electron microscope SEM sensitivity severe acute respiratory syndrome Coronavirus stability Template the receptor-binding domain was used X-ray spectroscopy [DOI] 10.1016/j.bios.2021.113729 PMC 바로가기 [Article Type] Article
Structure and function of a family of tick-derived complement inhibitors targeting properdinArticle Published on 2022-01-142022-10-04 Journal: Nature Communications [Category] 변종, 유전자 메커니즘, [키워드] Activation Alternative pathway approaches cascade cellular immune responses characterisation complement Complement inhibitor complement inhibitors complement response functional future therapeutic identify immune cells immunology inhibiting inhibitor magnitude positive promote properdin receptor reveal Saliva serum Structure triggers X-ray crystallography [DOI] 10.1038/s41467-021-27920-2 PMC 바로가기 [Article Type] Article
Delaying Intraoral Radiographs during the COVID-19 Pandemic: A ConundrumCOVID-19 전염병 동안 구강 내 방사선 사진 지연: 수수께끼Review Published on 2022-01-122022-09-12 Journal: BioMed Research International [Category] 진단, [키워드] applied can not Computed tomography Contamination coughing COVID-19 COVID-19 pandemic cross-contamination Cross-infection Dental Treatment dentist dentists Diagnosis diagnostic Efficacy emergency treatment extraoral followed by gag reflex Health Infection Not applied pandemic Patient professional protocol provide Radiograph Radiographic reducing Regulatory respiratory droplet Respiratory droplets risk Risk assessment Saliva secretion stimulate the patient Treatment treatment planning [DOI] 10.1155/2022/8432856 PMC 바로가기 [Article Type] Review
SARS-CoV-2 Saliva Mass Screening in Primary Schools: A 10-Week Sentinel Surveillance Study in Munich, GermanyArticle Published on 2022-01-112022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Asymptomatic children cohort study collected Community eight evaluated feasibility feasible Germany incidence rates mass Mass screening median age Munich participant participated participating children polymerase chain primary school primary schoolchildren processed Quantitative representing reverse transcription RT-qPCR Safe Saliva Salivette® SARS-CoV-2 SARS-COV-2 infection School Schools Screening secondary cases sentinel Spread Surveillance surveillance data tested women [DOI] 10.3390/diagnostics12010162 PMC 바로가기 [Article Type] Article
Setting-Up a Rapid SARS-CoV-2 Genome Assessment by Next-Generation Sequencing in an Academic Hospital Center (LPCE, Louis Pasteur Hospital, Nice, France)Medicine Published on 2022-01-112022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Analysis approach Aside assessment automated B.1.1.7 center collected Complete correlation COVID-19 detect Diagnosis Efficiency European feasibility France Genexus Genome sequencing highlight hospital Ion Laboratory limitation Louis Pasteur material Nasopharyngeal swab Next-generation sequencing next-generation sequencing (NGS) Rapid repeated reverse transcription-PCR RNA extraction routine clinical care Saliva SARS-CoV-2 SARS-CoV-2 positive individuals SARS-CoV-2 variant Sequencing single hospital the SARS-CoV-2 the SARS-CoV-2 genome These data variant variants variants of SARS-CoV-2 Viral genome sequencing Viral load was performed [DOI] 10.3389/fmed.2021.730577 PMC 바로가기 [Article Type] Medicine
A 2-month field cohort study of SARS-CoV-2 in saliva of BNT162b2 vaccinated nursing home workers Research Published on 2022-01-102022-10-05 Journal: Communications Medicine [Category] 유전자 메커니즘, 진단, [키워드] affected age Asymptomatic Belgium BNT162b2 mRNA circulating cohort study Comorbidities conducted Contact contributing to COVID-19 pandemic COVID-19 vaccine COVID‐19 COVID‑19 vaccine Efficacy examined fraction genotyped greater group identify knowledge management MONITOR mRNA mRNA BNT162b2 nursing home observé of BNT162b2 outbreak Pfizer positive sample Prevent Public health intervention Result RT-qPCR Saliva saliva specimen SARS-CoV-2 Screening second dose sequenced the SARS-CoV-2 triggered vaccination Variability variants of concern Viral load viral shedding Viral transmission were used wild-type virus [DOI] 10.1038/s43856-021-00067-3 [Article Type] Research
Oral cavity infection by the SARS-CoV-2: emphasizing the essence of masking and peptide therapeuticsCorrespondence Published on 2022-01-102022-11-01 Journal: The Egyptian Journal of Medical Human Genetics [Category] COVID-19, [키워드] ACE2 ACE2 receptor binding blood pressure homeostasis carried cathepsin L cellular cleavage conformational change COVID-19 cytoplasm disease epithelial function functions glycoprotein healthcare high expression level high risk host’s body human ACE2 receptor Infection information inhibit nucleocapsid oral cavity oral mucosa other proteases peptide Protease inhibitor Protein proteolytic cleavage Regulation Saliva SARS-CoV-2 secretion supplementary material therapeutic TMPRSS2 viral loads viral spike [DOI] 10.1186/s43042-022-00213-z PMC 바로가기 [Article Type] Correspondence
Validation of a Saliva-Based Test for the Molecular Diagnosis of SARS-CoV-2 InfectionResearch Article Published on 2022-01-072022-10-31 Journal: Disease Markers [Category] COVID-19, SARS, [키워드] 95% CI asymptomatic subject clinical sensitivity clinicians and researcher collected Collection Concordance conducted controls denaturing determine Diagnosis diagnostic effective enrolled gold standard IMPROVE Infection infective inhibiting internal Laboratory test lack molecular nasopharyngeal Negative predictive value NP swab NP swabs NPV offer pandemic Patient Population screening Positive predictive value PPV reduce Result risk RT-PCR RT-PCR assay saline solution Saliva saliva sample saliva samples SARS-CoV-2 sensitivity specificity Swab Test tested the SARS-CoV-2 Transport validation viral genome virus was performed [DOI] 10.1155/2022/6478434 PMC 바로가기 [Article Type] Research Article
Exploratory Study on Application of MALDI-TOF-MS to Detect SARS-CoV-2 Infection in Human SalivaArticle Published on 2022-01-062022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Accuracy Analysis appear application averaged caused collected Contamination Control convalescent patient COVID-19 COVID-19 diagnosis D30 diagnosing diagnostic discrepancy Enrollment FIVE gold standard healthcare healthy Human independent dataset infected individual invasive linear machine learning MALDI-TOF MS ML model molecular molecular test MS spectra Nasopharyngeal swab nine NPs outbreak performed proportion protocol provided quality control step reference test reliability RT-qPCR Saliva salivary SARS-CoV-2 SARS-CoV-2 positive patient sensitivity several limitations significantly specificity specimens Support tested training dataset treat two groups virus [DOI] 10.3390/jcm11020295 PMC 바로가기 [Article Type] Article