Compartmentalized Replication of SARS-Cov-2 in Upper vs. Lower Respiratory Tract Assessed by Whole Genome Quasispecies AnalysisArticle Published on 2020-08-262022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Analysis analyzed approach Bioinformatic clade Clustering collected coronavirus COVID-19 COVID-19 patients diagnosed Evolution Frequency genetic heterogeneity Genome heterogeneous identify intensive care unit Intra-host variability Ion Italy Lower Lower respiratory tract LRT NGS no significant difference nucleotide Patient patients Quasispecies quasispecy respiratory SARS-CoV-2 Sequencing Strains supported Thermofisher tract upper URT Variability variant virus replication was performed whole-genome [DOI] 10.3390/microorganisms8091302 PMC 바로가기 [Article Type] Article
Real-Time Forecasting of the COVID-19 Outbreak in Chinese Provinces: Machine Learning Approach Using Novel Digital Data and Estimates From Mechanistic ModelsOriginal Paper Published on 2020-08-172022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, [키워드] affected baseline catastrophic caused characteristic Chinese Clustering coronavirus coronavirus disease COVID-19 deaths Digital digital data digital epidemiology disease emerging outbreak estimate events example Forecasting Health Hybrid model hybrid simulation individual inherent machine learning machine learning in public health Mechanistic model media methodology Model modeling modeling disease outbreaks novel objective observation outbreak Outbreaks outperform pathogen Precision public health public health threat real time Result Simulation [DOI] 10.2196/20285 PMC 바로가기 [Article Type] Original Paper
Social Group Optimization–Assisted Kapur’s Entropy and Morphological Segmentation for Automated Detection of COVID-19 Infection from Computed Tomography ImagesArticle Published on 2020-08-152022-10-31 Journal: Cognitive Computation [Category] COVID-19, [키워드] Accuracy Basis caused Classifier clinically Clustering Computed tomography coronavirus disease COVID-19 COVID-19 infection CT scan image dataset decision detect detection diagnose Entropy Experimental result feature forest function fused Fused feature vector fusing global pandemic group high accuracy highest Image Infection infection rate initial KNN classifier lung Novel coronavirus offer principle Radial regions Research SARS-CoV-2 Segmentation Segmentation and detection accuracy severity Support support vector machine the disease threat tree [DOI] 10.1007/s12559-020-09751-3 PMC 바로가기 [Article Type] Article
Transferrin receptor 1 levels at the cell surface influence the susceptibility of newborn piglets to PEDV infectionResearch Article Published on 2020-07-302022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] activate Ammonium antibody Caco-2 caused Cell Clustering deficiency epidemic diarrhea expression Extracellular HEK 293T impair in vitro in vivo infect Infection infections inhibited interact intestinal intestinal epithelial cell intestinal epithelial cells iron accumulation iron deficiency mechanism Newborn Older over-expressed PEDV Phosphorylation promote provide receptor reduce reveal S1 protein susceptibility susceptible therapy These data tissue Transferrin Treatment tyrosine virus was increased [DOI] 10.1371/journal.ppat.1008682 PMC 바로가기 [Article Type] Research Article
A Clustering Approach to Classify Italian Regions and Provinces Based on Prevalence and Trend of SARS-CoV-2 CasesArticle Published on 2020-07-222022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Applying approach Characteristics Cluster Clustering coronavirus COVID-19 described effort Epidemic Epidemiology exhibited Hierarchical highest IMPROVE Italian Italian region Italy K-means clustering lockdown lowest management median MONITOR National offered positive positive cases Prevalence Region SARS-CoV-2 the epidemic the SARS-CoV-2 trend while [DOI] 10.3390/ijerph17155286 PMC 바로가기 [Article Type] Article
SARS-CoV-2 genomic variations associated with mortality rate of COVID-19Article Published on 2020-07-222022-10-04 Journal: Journal of Human Genetics [Category] MERS, SARS, 변종, 유전자 메커니즘, 치료법, [키워드] Affect analyses association caused Cluster Clustering conducted coronavirus disease correlation country COVID-19 deaths Factor fatality Fatality rate frequencies Frequency Genetic genomic variation Genotype global pandemic Hierarchical HLA HLA alleles Host Immunogenetics independent infected cases Infection investigated Linkage disequilibrium mortality rate mutant Mutation number of infected ORF1ab outbreak positive correlation S protein SARS-CoV-2 SARS-CoV-2 genome sequence SARS-COV-2 infection SARS-CoV-2 mutation SARS-CoV-2 sequence severity of COVID-19 significantly susceptibility variant variants [DOI] 10.1038/s10038-020-0808-9 PMC 바로가기 [Article Type] Article
Forecasting Covid-19 Dynamics in Brazil: A Data Driven ApproachArticle Published on 2020-07-152022-10-30 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] ANN approach baseline Brazil Brazilians carried Cluster Clustering confirmed case confirmed cases country COVID-19 pandemic data-driven distribution Dynamics estimate feature Final Forecasting identify Infection introduced Long MAE modified auto-encoder outcome pandemic Pandemics predict predicted Region representing retained Spread term the disease time series prediction [DOI] 10.3390/ijerph17145115 PMC 바로가기 [Article Type] Article
An Epidemiological Study on the Prevalence of the Clinical Features of SARS-CoV-2 Infection in Romanian PeopleArticle Published on 2020-07-142022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] affected Analysis clinical clinical feature Cluster Clustering component COVID-19 diagnostic dimension Health status individuals Infection Logistic regression analysis online survey participant Prevalence prevalence study principal reliability Romanian population SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic selected separated significant difference similarity social distancing socio-demographic Sociodemographic characteristics statistical statistically significant subjects the SARS-CoV-2 the SARS-CoV-2 virus variables [DOI] 10.3390/ijerph17145082 PMC 바로가기 [Article Type] Article
Asymptomatic and Symptomatic Patients With Non-severe Coronavirus Disease (COVID-19) Have Similar Clinical Features and Virological Courses: A Retrospective Single Center StudyMicrobiology Published on 2020-06-262022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] analyzed association Asymptomatic asymptomatic patient bilateral pneumonia center Chest computed tomography Chest CT Chinese clinical clinical feature Clustering coronavirus disease Course COVID-19 COVID-19 patient CT scan defined demographic evaluate Follow-up had more had no hospital initial laboratory-confirmed less outbreak pandemic Patient patients Pneumonia Probability progression retrospective SARS-CoV-2 single center symptomatic symptomatic patient Symptomatic patients symptomatic status the disease Transmission treated Virological without symptom World Health Organization Wuhan, China [DOI] 10.3389/fmicb.2020.01570 PMC 바로가기 [Article Type] Microbiology
Phylogenetic analysis of SARS-CoV-2 genomes in TurkeyArticle Published on 2020-06-212022-10-29 Journal: Turkish Journal of Biology [Category] COVID-19, [키워드] acute respiratory syndrome Analysis carried Clustering coronavirus country COVID-19 Evolution Genome genome sequence genomes genomic independent Infection International isolate performed Phylogenetic Phylogenetic analysis Phylogenetic tree phylogenetics released reported SARS-CoV-2 SARS-CoV-2 genome sequenced Spread subtype suggested Transmission Turkey virus virus genome virus isolate virus spread [DOI] 10.3906/biy-2005-35 PMC 바로가기 [Article Type] Article