Randomized clinical trial to compare the efficacy of ivermectin versus placebo to negativize nasopharyngeal PCR in patients with early COVID-19 in Peru (SAINT-Peru): a structured summary of a study protocol for randomized controlled trial
페루의 초기 COVID-19 환자(SAINT-Peru)에서 비인두 PCR을 무효화하기 위해 이버멕틴 대 위약의 효능을 비교하기 위한 무작위 임상 시험(SAINT-Peru): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약
Letter
[키워드] 1:1
Administered
adverse event
allergy
Amiodarone
Anosmia
Antiviral
attending physician
baseline
blinded
Blinding
block
childbearing age
clarithromycin
clinical
clinical and laboratory parameters
clinical care
clinical trial
Cobicistat
coin
conducted
control group
correlation
cough
COVID-19
COVID-19 disease
COVID-19 patient
COVID-19 pneumonia
COVID-19 progression
criteria
Critical
current
cyclosporine
CYP3A4
daily dose
death
determine
determined by
diagnosed
diagnostic test
Diltiazem
dissemination
dose
drug
early treatment
Efficacy
element
Eligible patients
emergency services
enrolled
epidemiologist
erythromycin
evaluate
expected
Fever
follow-up visits
generate
hospital
Hospitalization
IgA
IgG
IgM
IIa
immune response
immunomodulatory
in vivo
include
inclusion criteria
Indinavir
Infection
Informed consent
inhibitor
Intervention
intestinal
investigator
investigators
involved
itraconazole
Ivermectin
ketoconazole
laboratory parameter
less
list
lung
magnitude
medical staff
nasopharyngeal
nasopharyngeal specimen
Nasopharyngeal swab
nasopharyngeal swab PCR
nasopharyngeal swabs
National
negative
number
objective
Older
outcome
oxygen
oxygen saturation
Parallel Arm
participant
Patient
patients
patients with SARS-CoV-2
PCR
PCR cycle
Peru
Pharmacist
phase
Placebo
placebo group
placebo-controlled trial
Pneumonia
positive
positive PCR test
positive SARS-CoV-2 PCR
pregnancy test
pregnant women
principal investigator
progression
proportion
protocol
quinidine
randomization list
Randomized
Randomized controlled trial
Randomly
Rapid diagnostic test
receive
recruited
reduce
Registered
Registration
Result
risk factor
Risk factors
Ritonavir
Sample size
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 PCR
SARS-CoV-2 RNA
SARS-CoV-2 viral load
secondary
Secondary objectives
Seroconversion
Seven
severe disease
severity
spironolactone
statistician
status
study population
Study protocol
supplementary material
Symptom
symptomatic
Symptomatology
Symptoms
tacrolimus
the patient
the placebo group
the SARS-CoV-2
threshold
Treatment
treatment group
treatment groups
treatment initiation
Trial
Trial registration
two group
two groups
verapamil
Viral
Viral load
virus
Warfarin
website
with COVID-19
women
[DOI] 10.1186/s13063-021-05236-2 PMC 바로가기 [Article Type] Letter
[DOI] 10.1186/s13063-021-05236-2 PMC 바로가기 [Article Type] Letter