Functional mapping of B-cell linear epitopes of SARS-CoV-2 in COVID-19 convalescent populationResearch Article Published on 2020-09-172022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS, [키워드] antibody B-cell blocked caused composed convalescent convalescent sera COVID-19 Diagnosis Dilution dominant epitope Efficacy elicit elicited epitope FIVE indicated Interaction linear epitope membrane mortalities neutralization activity Neutralizing neutralizing antibody Non-COVID-19 overlapped pandemic peptide performed Proteins SARS-CoV-2 SARS-CoV-2 vaccine sera specific antigen the vaccine Vaccine vaccine candidate viral infection [DOI] 10.1080/22221751.2020.1815591 PMC 바로가기 [Article Type] Research Article
It is unprecedented: trial management during the COVID-19 pandemic and beyondCommentary Published on 2020-09-112022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] activities activity assessment clinical clinical trial clinical trials Community Complete COVID-19 COVID-19 pandemic example group Intervention management many cases National network Non-COVID-19 pandemic participant patient safety professional provided recruitment Research risk technology Trial Trial management trials unique [DOI] 10.1186/s13063-020-04711-6 PMC 바로가기 [Article Type] Commentary
The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal–fetal transmission: a systematic review and meta-analysisReview Published on 2020-09-042022-10-31 Journal: European Journal of Medical Research [Category] COVID-19, SARS, [키워드] admitted to ICU Affect alteration analyzed angiotensin-converting enzyme-2 article Bilateral C-reactive protein Care cells Clinical course clinical feature clinical manifestations clinical symptom Cochrane Library Complication conducted coronavirus Coronavirus infection cough CoV COVID-19 death demonstrated diagnosed died distress fetal Fever General population gestation Google Scholar gravid greater ground-glass opacity growth Health Hydroxychloroquine Immunocompromised increased risk Infection Infectious disease Laboratory low expression Lung volume lymphocytopenia membrane MERS-CoV Meta-analysis Middle East respiratory syndrome mother myalgia Neonatal Neonate Non-COVID-19 Novel coronavirus-2019 occurred outcome outcomes Oxygen therapy Patient physiological change Pneumonia Pregnancy pregnant pregnant women Premature Preterm birth Prevalence ranged reported respiratory Result ribavirin risk rupture SARS-CoV SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus-2 study period systematic review Transmission Treatment vertical transmission Web of Science [DOI] 10.1186/s40001-020-00439-w PMC 바로가기 [Article Type] Review
SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19Research Published on 2020-09-042022-10-29 Journal: Journal of Hematology & Oncology [Category] COVID-19, SARS, [키워드] ACE2 ACE2 expression aggregates aggregation bind binding blood stream cardiovascular complications CD62P changes in Coagulation factors coagulation parameter condition correlated COVID-19 COVID-19 patient COVID-19 patients Critical Critically ill patient critically ill patients decrease demonstrated develop diagnosed with COVID-19 downstream ENhance evaluated Evidence Ex vivo expressed expression facilitate flow cytometry functional hACE2 healthy volunteers host cell receptor human Ace2 protein hyperactivity immunofluorescence in vitro in vivo inflammatory factors Inflammatory response inhibit SARS-CoV-2 investigated MAPK mice monoclonal antibody MPV Non-COVID-19 PAC-1 pathogenesis of COVID-19 pathway Platelet platelet activation Platelets priming pro-thrombotic Protein provided recombinant responsible Result risk RT-PCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 virus secretion serine protease spike stimulated thrombosis thrombotic event thrombus formation TMPRSS2 transfused transgenic transgenic mice Volume wild-type [DOI] 10.1186/s13045-020-00954-7 PMC 바로가기 [Article Type] Research
18 FDG-PET/CT findings in COVID-19: a single centre retrospective radiological reviewCase Review Published on 2020-09-012022-10-27 Journal: BJR | Case Reports [Category] COVID-19, [키워드] acute respiratory syndrome Asymptomatic Asymptomatic case cause classic coronavirus COVID-19 COVID-19 positive patient COVID-19 positive patients described Endemic evaluated FDG global pandemic highlighting Infection Infectious disease Local low dose manifestation Non-COVID-19 nuclear performed PET/CT physician protocol radiological radiologist retrospective SARS-CoV-2 symptomatic patient the disease with COVID-19 [DOI] 10.1259/bjrcr.20200091 PMC 바로가기 [Article Type] Case Review
Reduced Emergency Department Utilization During the Early Phase of the COVID-19 Pandemic: Viral Fear or Lockdown Effect?Brief Report Published on 2020-08-122022-10-31 Journal: Disaster Medicine and Public Health Preparedness [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] Admission changes in chi-square tests Combined complex interaction coronavirus disease country COVID-19 COVID-19 pandemic declined defined delivery of health care Department early phase Effect Emergency emergency preparedness emergency service hospital expressed fear hospital Local lockdown Non-COVID-19 observation pandemic Pandemics phase primary care reduced reduction in reflect Research Retrospective analysis study period utilization Volume was performed was used [DOI] 10.1017/dmp.2020.303 PMC 바로가기 [Article Type] Brief Report
Essential health services delivery in Zimbabwe during the COVID-19 pandemic: perspectives and recommendationsPerspectives Published on 2020-08-112022-10-28 Journal: The Pan African Medical Journal [Category] Coronavirus, MERS, SARS, [키워드] Adequate Care cause chronic condition COVID-19 delays Essential Health Health Service Health services health services delivery healthcare Healthcare provision Healthcare system healthcare worker Infection prevention Local lockdowns measure morbidity morbidity and mortality Non-COVID-19 occurred Patient patients Perspective Public health interventions recommendation reported reproductive SARS-CoV-2 seeking Spread World Health Organisation Zimbabwe [DOI] 10.11604/pamj.supp.2020.35.143.25367 PMC 바로가기 [Article Type] Perspectives
Diagnostic accuracy of initial chest radiograph compared to SARS-CoV-2 PCR in patients with suspected COVID-19Original Research Published on 2020-08-052022-10-28 Journal: BJR Open [Category] COVID-19, [키워드] Accuracy advance Analysis blinded Chest clinical suspicion Cohort cohort of patient consecutive patient COVID-19 CT scan CXR determine diagnosis of COVID-19 diagnostic Diagnostic accuracy disease hospital initial Non-COVID-19 not differ pathology Patient PCR PCR positive PCR tests polymerase chain predominant presenting Prevalence radiologist reference test reported reporter SARS-CoV-2 SARS-CoV-2 PCR sensitivity significantly specificity subset Thoracic [DOI] 10.1259/bjro.20200034 PMC 바로가기 [Article Type] Original Research
Diagnostic utility of additional whole-chest CT as part of an acute abdominal pain CT imaging pathway during the COVID-19 pandemicResearch article Published on 2020-08-012022-10-05 Journal: Clinical radiology [Category] SARS, 진단, [키워드] abdominal pain anatomical approach base category Chest clinical feature clinically clinically suspected Cohort cohort of patients Computed tomography correlation COVID-19 COVID-19 pandemic defined determine diagnostic distribution evaluate evaluated feature lung Lung disease Non-COVID-19 offer pathway Patient Pneumonia positive retrospective RT-PCR utility were assessed [DOI] 10.1016/j.crad.2020.06.002 [Article Type] Research article
Predicting COVID-19 Pneumonia Severity on Chest X-ray With Deep LearningEmergency Medicine Published on 2020-07-282022-10-31 Journal: Cureus [Category] COVID-19, [키워드] blinded can be used Care chest X-ray Chest X-ray images Coronavirus disease-19 COVID-19 COVID-19 pneumonia database dataset deep deep learning artificial intelligence Efficacy Escalation feature ICU Image learning lung Lung infection lung involvement MAE management mean absolute error MONITOR Non-COVID-19 Non-invasive Patient Pneumonia predict Predictive progression Regression model Result scored severity severity of COVID-19 severity scoring Streamline subset the disease Treatment X-ray [DOI] 10.7759/cureus.9448 PMC 바로가기 [Article Type] Emergency Medicine