Cross-reactivity of antibodies from non-hospitalized COVID-19 positive individuals against the native, B.1.351, B.1.617.2, and P.1 SARS-CoV-2 spike proteins근원이없는 COVID-19 긍정적 인 개체로부터의 항체의 교차 반응성, B.1.351, B.1.617.2 및 p.1 SARS-COV-2 스파이크 단백질Article Published on 2021-11-082022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] ACE-2 ACE-2 receptor Adults affinity analyzed antibodies antibody antibody level antibody levels B.1.351 B.1.617.1 B.1.617.2 Beta BNT162b2 ChAdOx1 ChAdOx1 nCoV-19 collected COVID-19 cross-reactivity Delta ectodomain Effectiveness elicited enrolled Evidence evidence of except for Gamma humoral Humoral response implication individual individuals infected with SARS-CoV-2 inhibited Interaction interactions nCoV neutralization Optical sensors P.1 P.1 variant pandemic PCR-confirmed positive individual Proteins relative SARS-CoV-2 spike SARS-CoV-2 spike protein SARS-CoV-2 variant SARS-CoV-2 variants sera Spike protein Spike proteins SPR Spread sustained the spike protein vaccinated individual vaccinated individuals vaccination variant spike VoC VOCs [DOI] 10.1038/s41598-021-00844-z PMC 바로가기 [Article Type] Article
A review of epidemiology, clinical features and disease course, transmission dynamics, and neutralization efficacy of SARS-CoV-2 variantsReviews Published on 2021-11-062022-10-31 Journal: The Egyptian Journal of Bronchology [Category] COVID-19, [키워드] addition article association available data Body Characteristics Clinical characteristics clinical feature clinical trial Comparative containment measures convalescent sera COVID 19 COVID-19 cross-protection described disease course Effectiveness Efficacy Epidemiology Evidence finding Genome geographical distribution heat map hindrance immune evasion Immunity literature review mAb mAbs methodology MONITOR monoclonal antibody Mutation neutralization neutralization potency pandemic provided resulting RNA viruses SARS CoV-2 SARS-CoV-2 SARS-CoV-2 variant sera several variant severity Spread therapeutic option Transmissibility Transmission dynamics Vaccination strategy Vaccine vaccine immunity Vaccines variant variants variants of interest Viral load virulence virus VoC was performed Wuhan strain [DOI] 10.1186/s43168-021-00090-x PMC 바로가기 [Article Type] Reviews
564. SARS-CoV-2 Ferritin Nanoparticle Vaccines Elicit Broad SARS Coronavirus ImmunogenicityPoster Abstracts Published on 2021-11-042022-10-29 Journal: Open Forum Infectious Diseases [Category] COVID-19, [키워드] analyzed antibody antigenic approach binding breadth clinical trial Combination domain elicit elicited Emergency use authorization global pandemic Heterologous High-dose highlight immune response immunization immunogen immunogenicity K18-ACE2 K18-hACE2 mice Multiple murine mutations N-terminal domain nanoparticle neutralization Neutralizing NTD observation pandemic platform prefusion pseudovirus RBD reported responses Result robust SARS-CoV RBD SARS-CoV-1 SARS-CoV-1 RBD SARS-CoV-1 virus SARS-CoV-2 SARS-CoV-2 neutralizing antibody SARS-CoV-2 RBD SARS-CoV-2 variant SARS-CoV-2 virus SARS-CoV-2 virus variant SARS-like coronavirus sera spike the SARS-CoV-2 transfused transgenic mice Transgenic mouse Vaccine Vaccine design vaccine platform variant variants of concern virus were assessed zoonotic [DOI] 10.1093/ofid/ofab466.762 PMC 바로가기 [Article Type] Poster Abstracts
Link between serum lipid signature and prognostic factors in COVID-19 patientsCOVID-19 환자의 혈청 지질 특징과 예후 인자 사이의 연관성Article Published on 2021-11-042022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 임상, 치료기술, [키워드] (C-reactive protein) Affect affected age Analysis analyzed Biomarker C-reactive protein ceramide Coagulation COVID-19 COVID-19 patient COVID-19 patients creatinine Critical D-dimer Defense Disease progression disease progression and severity dyslipidemia Effect exhibited FIVE Horowitz hypoxia identify impairment index Inflammation Kidney function Lipid Lipidomics lipids MONITOR outcome outcomes oxidative stress Patient Prognostic factor Prognostic factors Prognostic markers reduced respiratory respiratory tract sera serum serum lipid Serum lipids severity sphingomyelin sphingomyelins sulfatide the disease the patient translation Viral viral infection [DOI] 10.1038/s41598-021-00755-z PMC 바로가기 [Article Type] Article
Development of a rapid point-of-care test that measures neutralizing antibodies to SARS-CoV-2Article Published on 2021-11-042022-10-04 Journal: Journal of Clinical Virology [Category] MERS, SARS, 진단, [키워드] ACE2 angiotensin-converting enzyme 2 assays baseline binding Blood COVID-19 COVID-19 vaccine demonstrated development dose individual individuals infected individual infected individuals Infection lateral flow lateral flow assay measure microneutralization mRNA vaccine neutralization Neutralizing activity Neutralizing antibodies neutralizing antibody non-infected Patient patients with COVID-19 plasma point-of-care RBD receiving recipient respiratory virus Result ROC Curve SARS-CoV-2 SARS-CoV-2 microneutralization assay seasonal coronavirus second dose semi-quantitative sera tested the receptor-binding domain vaccine dose vaccine doses Whole blood [DOI] 10.1016/j.jcv.2021.105024 PMC 바로가기 [Article Type] Article
Timing of SARS-CoV-2 vaccination during the third trimester of pregnancy and transplacental antibody transfer: a prospective cohort studyOriginal Article Published on 2021-11-032022-10-04 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome Administered age Antenatal anti-S antibody antibody transfer Blood collected Concentration Cord blood coronavirus Coronavirus disease 2019 domain ENhance evaluated first dose gestation greater highlight IgG IgG level immunization immunized interquartile range IQR Maternal median mRNA vaccination Neonatal Neutralizing neutralizing antibody objective passive immunity placental positive positively correlated Pregnancy pregnant women prospective cohort study RBD Result SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 BNT162b2 SARS-CoV-2 spike protein SARS-CoV-2 vaccination sera serology severe acute respiratory syndrome coronavirus 2 study cohort transfer vaccination vaccine dose [DOI] 10.1016/j.cmi.2021.10.003 PMC 바로가기 [Article Type] Original Article
Comparison of Estimated Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence Through Commercial Laboratory Residual Sera Testing and a Community Survey상업용 실험실 잔류 혈청 검사 및 지역 사회 조사를 통한 추정된 중증 급성 호흡기 증후군 코로나바이러스 2 혈청 유병률의 비교Article Published on 2021-11-022022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome Atlanta Community convenience sampling coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 (COVID-19) estimate Estimated Laboratory residual respiratory SARS-CoV-2 sera Seroprevalence severe acute respiratory syndrome–related coronavirus 2 (SARS-CoV-2). survey Testing [DOI] 10.1093/cid/ciaa1804 PMC 바로가기 [Article Type] Article
Quaternary Ammonium Compounds: Bioaccumulation Potentials in Humans and Levels in Blood before and during the Covid-19 Pandemic4차 암모늄 화합물: 코비드-19 팬데믹 이전과 동안 인간의 생물학적 축적 가능성과 혈액 내 수준Article Published on 2021-11-022022-09-11 Journal: Environmental science & technology [Category] SARS, 치료기술, 치료제, [키워드] Ammonium Analysis binding Bioaccumulation Biomonitoring Blood blood sample Blood samples build clearance rate collected Compound Concentration consumer COVID-19 COVID-19 pandemic Disinfectants epidemiological experiments group Human In vitro−in vivo extrapolation (IVIVE) in vivo information Level median metabolism outbreak pandemic pharmaceutical Potential Protein binding Quaternary ammonium compounds (QACs). risk Risk assessment sera Serum protein significantly higher these compound these compounds variety [DOI] 10.1021/acs.est.1c01654 PMC 바로가기 [Article Type] Article
IgG Study of Blood Sera of Patients with COVID-19Article Published on 2021-11-022022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] affected affecting analyzed antibody antibody specificity Blood Comorbidity convalescent country COVID-19 COVID-19 pandemic cross-reactive antibody cross-reactivity death descending diagnosed with COVID-19 died disease disease severity ELISA Factor Frankfurt hospital humoral Humoral immunity IgG immunoblotting inactivated Infection levels of antibody median value neutralization neutralization test neutralize Neutralizing activity neutralizing antibody Patient presence of antibody RBD recombinant proteins SARS-CoV SARS-CoV antigen SARS-CoV-2 sera serum severity tested the N protein trimer Virus neutralization with COVID-19 Wuhan [DOI] 10.3390/pathogens10111421 PMC 바로가기 [Article Type] Article
Neutralizing antibody responses following natural SARS-CoV-2 infection: Dynamics and correlation with commercial serologic tests자연적인 SARS-CoV-2 감염에 따른 중화 항체 반응: 상업적 혈청학적 검사와의 역학 및 상관관계Article Published on 2021-11-012022-09-11 Journal: Journal of Clinical Virology [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] allocation anti-SARS-CoV-2 Anti-spike Antibody Response Antibody titer Antibody titers assays booster doses correlation COVID-19 cross-reactivity demonstrated detect diagnostic domain Dynamics Efficacy Elecsy Elecsys ELISA Euroimmun evaluate evaluated except for facilitate Follow-up healthcare worker IgG immunoassay immunoassays long term MONITOR NAbs Neutralizing antibodies Neutralizing antibody response neutralizing capacity participant participated performed plaque reduction neutralization Post-vaccine Protein reference standard SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 immunity SARS-COV-2 infection SARS-CoV-2 neutralizing antibodies sera serologic test serologic tests seronegative seroprevalence survey significant decrease Support the immunoassay total antibodies vaccination [DOI] 10.1016/j.jcv.2021.104988 PMC 바로가기 [Article Type] Article