Microvascular flow alterations in critically ill COVID-19 patients: A prospective studyResearch Article Published on 2021-02-082022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] 48 hour alteration Blood Cell COVID-19 COVID-19 patient Critical Critically ill Critically ill patient finding group Health Organization heterogeneity ICU ICU admission mechanical ventilation mechanically ventilated MFI Microscopy non-ventilated patients parameter Patient PPV proportion Prospective Study severe group severity significantly higher single-center Sublingual the disease vessel were assessed [DOI] 10.1371/journal.pone.0246636 PMC 바로가기 [Article Type] Research Article
Hematological and biochemical abnormalities associated with severe forms of COVID-19: A retrospective single-center study from Morocco심각한 형태의 COVID-19와 관련된 혈액학적 및 생화학적 이상: 모로코의 후향적 단일 센터 연구Observational Study Published on 2021-02-042022-09-10 Journal: PLoS ONE [Category] MERS, 임상, 치료기술, [키워드] Abnormalities abnormality Admission advanced age affected African age Alanine alanine aminotransferase Analysis analyzed aspartate Aspartate aminotransferase biochemical biological parameter biological parameters Blood cells C-reactive protein Characteristics clinical clinician Cohort Comorbidities conducted coronavirus coronavirus disease COVID-19 creatinine Critical disease CRP D-dimers deaths detect died disease Disease progression early stage environmental factor Epigenetic Evolution Factor ferritin form Genetic Genetic studies group Health Health crisis Health Sciences Hospitalization Hospitalized identify immunological individual Infection Lactate lactate dehydrogenase LDH literature review Lymphocytes male Male sex median age Mild mild to moderate mild to moderate disease moderate moderate disease MONITOR Morocco Neutrophils non-severe patients North pandemic parameter Patient patients older Predictive presence of comorbidities procalcitonin progression radiological retrospective Retrospective study risk factor Risk factors severe and non-severe patients severe disease severity single-center single-center study survived the median Univariate analysis university was performed WBC White blood cell White blood cells [DOI] 10.1371/journal.pone.0246295 PMC 바로가기 [Article Type] Observational Study
Tocilizumab for the treatment of adult patients with severe COVID-19 pneumonia: A single-center cohort study중증 COVID-19 폐렴 성인 환자의 치료를 위한 Tocilizumab: 단일 센터 코호트 연구Article Published on 2021-02-012022-09-11 Journal: Journal of medical virology [Category] MERS, SARS, 진단, 치료제, [키워드] 6-point ordinal scale 95% confidence interval adjusted odds ratio adverse events all-cause mortality analyzed Body body temperature C-reactive protein cardiac rate cardiac rates clinical Clinical improvement clinical status cohort study consecutive patient coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia cytokine release decrease dose dropped Evidence hospital discharge hyperinflammatory phase immunomodulation immunomodulatory therapy interferon intravenous Laboratory Lactate lactate dehydrogenase lead lymphocyte Lymphocyte count monoclonal antibody Mortality Ordinal Scale outcome oxygen oxygen saturation Patient Pneumonia Primary outcome pulse oximetry Rate receptor respiratory Safe SARS-CoV-2 secondary Secondary outcomes serum lactate severe COVID-19 Severe COVID-19 pneumonia significantly single-center single-center study TCZ temperature Tocilizumab Treatment vital sign vital signs with COVID-19 [DOI] 10.1002/jmv.26308 PMC 바로가기 [Article Type] Article
SARS-CoV-2 diagnostics in the virology laboratory of a University Hospital in Rome during the lockdown period폐쇄 기간 동안 로마에 있는 대학 병원의 바이러스 연구소에서 SARS-CoV-2 진단Article Published on 2021-02-012022-09-11 Journal: Journal of medical virology [Category] Fulltext, MERS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 affected age Analysis analyzed Bronchoalveolar lavage cerebrospinal cerebrospinal fluid China confirmed case continuous surveillance coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 diagnostics Epidemiology Evolution fluids gargle highlighting individuals Infection infections information Italian regions Italy Laboratory laboratory diagnostics. lockdown male nasopharyngeal swabs pandemic Patient pleural fluids positive result reached respiratory Respiratory samples Rome SARS-CoV-2 SARS-CoV-2 epidemiology Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Sex single-center specimen spread to Stool stools subject Surveillance tested university Variation Virology virus [DOI] 10.1002/jmv.26332 PMC 바로가기 [Article Type] Article
Clinical characteristics of adult patients hospitalized with laboratory-confirmed COVID-19 pneumonia실험실에서 확인된 COVID-19 폐렴으로 입원한 성인 환자의 임상적 특징Article Published on 2021-02-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] SARS, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome Adult patients analyzed asymptomatic infection case sery Characteristics clinical Clinical characteristics Comorbidity coronavirus cough country COVID-19 COVID-19 pneumonia CRP diabetes Diabetes Mellitus died discharged Elderly patient elderly patients elevated eventually death Fever followed by heart disease heterogeneity hypertension ischemic heart disease İstanbul laboratory-confirmed leukopenia lymphocytopenia mortality rate mortality rates Outbreaks outcome overall mortality Patient patient cohort patient cohorts patients patients hospitalized patients with COVID-19 Pneumonia provide respiratory distress Retrospective study Shortness of breath single-center Symptom syndrome Treatment strategies Turkey Variation [DOI] 10.1016/j.jiac.2020.10.020 PMC 바로가기 [Article Type] Article
Hydroxychloroquine/azithromycin treatment, QT interval and ventricular arrhythmias in hospitalised patients with COVID-19Observational Study Published on 2021-02-012022-10-05 Journal: International journal of clinical practice [Category] SARS, 임상, [키워드] age arrhythmia association calculated Cohort Combination combination therapy Comorbidities COVID-19 death determine drug electronic medical records evaluate evaluated Factor HCQ hospitalised patient hospitalized COVID-19 patient hospitalized patients implication in both groups in-hospital mortality incidence initial men novel coronavirus disease occurred off-label Patient patients with COVID-19 Prospective Study QT interval QTc QTc interval QTC prolongation retrospective significant increase significantly higher single-center therapy Treatment treatment regimens two group ventricular with COVID-19 ΔQTc [DOI] 10.1111/ijcp.13896 PMC 바로가기 [Article Type] Observational Study
Effect of Convalescent Plasma in Critically Ill Patients With COVID-19: An Observational StudyMedicine Published on 2021-01-282022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 28-day mortality acute respiratory distress syndrome age Analysis baseline Biomarker Brazil clinical Clinical improvement conducted convalescent plasma coronavirus coronavirus disease COVID-19 COVID-19 patient Critically ill patient disease Effect Efficacy Final Follow-up hazard ratio IgG titer Ill increase in inflammatory activity IQR Kaplan–Meier laboratory-confirmed life-threatening Lymphocyte count mechanically ventilated occurred outcome Patient patients performed plasma prospective observational study reduced Registered registry Respiratory failure Rio de Janeiro secondary single-center Standard of care Study protocol survival therapeutic option viral loads with COVID-19 [DOI] 10.3389/fmed.2021.630982 PMC 바로가기 [Article Type] Medicine
Lung Auscultation of Hospitalized Patients with SARS-CoV-2 Pneumonia via a Wireless StethoscopeResearch Paper Published on 2021-01-282022-10-29 Journal: International Journal of Medical Sciences [Category] COVID-19, [키워드] affected analyzed Auscultation case sery Characteristics clinical collected COVID-2019 crackle Critically ill patient cross-sectional dead enrolled hospitalized patient Laboratory lung material moderate Patient patients Pneumonia poor prognosis positive predict prevalent Prognosis radiological recorded SARS-CoV-2 SARS-CoV-2 pneumonia severe group Severe patient single-center Stethoscope Treatment wheezing wireless Wuhan, China [DOI] 10.7150/ijms.54987 PMC 바로가기 [Article Type] Research Paper
ACE Gene I/D Polymorphism and Acute Pulmonary Embolism in COVID19 Pneumonia: A Potential Predisposing RoleMedicine Published on 2021-01-212022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] absence ACE ACE gene ACE2 activity Angiotensin II assessment case-control study conducted counterbalance COVID-19 COVID-19 disease COVID-19 patient COVID19 COVID19 pneumonia Embolism expressed genetic risk factor genetic susceptibility heterozygote high risk homozygous I/D I/D polymorphism Infection investigated involved Italy MOST Naple Occurrence Patient patients with SARS-CoV-2 pilot study Pneumonia polymorphism Population Potential Prevalence pulmonary pulmonary angiography Pulmonary embolism retrospective role Severe COVID-19 pneumonia significantly higher significantly lower single-center statistically significant difference subject thromboembolic complication Thromboembolism unit [DOI] 10.3389/fmed.2020.631148 PMC 바로가기 [Article Type] Medicine
Short-Term Variations in Neutrophil-to-Lymphocyte and Urea-to-Creatinine Ratios Anticipate Intensive Care Unit Admission of COVID-19 Patients in the Emergency DepartmentMedicine Published on 2021-01-202022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI Admission calculate calculated case-control study changes in clinical collected Comparisons Control controls COVID-19 COVID-19 severity criteria Definitive Department disease disease severity early stage Emergency identify increases in independent predictor intensive care intensive care unit Laboratory laboratory-confirmed Lymphocyte count median multivariable logistic regression neutrophil count Neutrophil-to-lymphocyte ratio Odds ratio parameter Patient Ratio retrospective severe COVID-19 single-center urea-to-creatinine ratio variables was performed with COVID-19 [DOI] 10.3389/fmed.2020.625176 PMC 바로가기 [Article Type] Medicine