Comparison and Sensitivity Evaluation of Three Different Commercial Real-Time Quantitative PCR Kits for SARS-CoV-2 DetectionSARS-COV-2 탐지를위한 3 가지 상이한 상업적 실시간 정량적 PCR 키트의 비교 및 민감도 평가Article Published on 2021-07-082022-09-01 Journal: Viruses [Category] SARS, 변종, 진단, 치료기술, [키워드] Accuracy amplification analytical sensitivity appearance association average Chain Reaction comparable COVID-19 Ct values cut-off detection diagnosis of SARS-CoV-2 diagnostic Diagnostic accuracy diagnostic efficacy Diagnostic method evaluated Final gene amplification gold hospitalized COVID-19 patients imperative indicate Infection isolate lowest Modification molecular testing N gene nucleic acid ORF1 ORF1ab PCR PCR kits PCR reaction performed polymerase chain polymerase chain reaction positive primer set primer sets randomly selected sample Real-time PCR Real-Time Reverse Transcription Polymerase Chain Reaction reverse transcription RNA RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV-2 nucleic acid significantly similarity statistically TaqPath variants [DOI] 10.3390/v13071321 PMC 바로가기 [Article Type] Article
The Reliability and Quality of YouTube Videos as a Source of Public Health Information Regarding COVID-19 Vaccination: Cross-sectional StudyOriginal Paper Published on 2021-07-082022-10-31 Journal: JMIR Public Health and Surveillance [Category] COVID-19, [키워드] “COVID-19 addressed Analysis authors categories Characteristics code collaboration COVID-19 COVID-19 vaccination COVID-19 vaccine criteria cross-sectional dissemination Efficacy engage English language evaluate foundation health information highest independent infodemiology information IQR knowledge lowest median medium moderate objective organization organizations platform produced professional professionals provide Public public health Public health intervention public health measures Quality ranged recent Regulatory reliability Result scored screened searched Side effect significantly higher social media Source understanding vaccination Vaccine vaccine trial video web-based health information YouTube [DOI] 10.2196/29942 PMC 바로가기 [Article Type] Original Paper
COVID-19 pandemic in BRICS countries and its association with socio-economic and demographic characteristics, health vulnerability, resources, and policy responseShort Report Published on 2021-07-082022-10-29 Journal: Infectious Diseases of Poverty [Category] COVID-19, [키워드] Abstract addition Additive Administered analyzed Associated factors association Brazil BRICS BRICS countries China conducted confirmed case confounders correlated country COVID-19 COVID-19 case COVID-19 epidemic COVID-19 pandemic cross-sectional demographic characteristics Demographic factors diabete Effect effective extreme Factor GDP Generalized growth Health health system highest hospital increase in India Infection lowest management Model pandemic Policy response Prevalence proportion public health emergency ranged reducing Resilience resources respond response Result Russia sensitivity analysis South Africa Strong Structure vaccine dose [DOI] 10.1186/s40249-021-00881-w PMC 바로가기 [Article Type] Short Report
Prevalence of neutralising antibodies against SARS-CoV-2 in acute infection and convalescence: A systematic review and meta-analysis급성 감염 및 회복기에서 SARS-CoV-2에 대한 중화항체의 유병률: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-07-082022-09-12 Journal: PLoS Neglected Tropical Diseases [Category] Coronavirus, SARS, 진단, [키워드] 95%CI acute infection adaptive antibodies antibody asymptomatic infection asymptomatic infections Author coronavirus disease correlated correlation covariate covariates cut off detectable develop disease severity elicit examined functional highlight IgG Immunity Immunoglobulin Immunoglobulin G immunoglobulins immunological responses individual infected with SARS-CoV-2 Infection International investigated likelihood lowest marker Meta-analysis Mild Neutralising Antibodies neutralising antibody Patient proportion protocol reference standard reflected respiratory SARS-CoV-2 SARS-CoV-2 antibodies SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 neutralising antibodies SARS-CoV-2 neutralising antibody selected Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus-2 severe coronavirus disease severe COVID-19 study group systematic review titre titres Variation [DOI] 10.1371/journal.pntd.0009551 PMC 바로가기 [Article Type] Meta-Analysis
The effect of methotrexate and targeted immunosuppression on humoral and cellular immune responses to the COVID-19 vaccine BNT162b2: a cohort studyArticles Published on 2021-07-082022-10-29 Journal: The Lancet Rheumatology [Category] COVID-19, [키워드] 95% CI All participant B.1.1.7 variant BNT162b2 BNT162b2 vaccine Cellular immune response cellular response clinical effectiveness Cohort cohort study consecutive patient Control controls Coverage COVID-19 vaccine COVID-19 vaccine trials defined determine Diagnosis Dilution East eligible England evaluate evaluated extended interval females finding first dose foundation funding groups healthy control healthy controls humoral Humoral immunity IL-17 IL-2 IL-21 IL-23 immune response Immune-mediated inflammatory disease immunogenicity Immunosuppressant Immunosuppression individual inhibitors inhibitory interferon-γ IQR London lowest males median median age methotrexate monotherapy Necrosis neutralising antibody response Neutralising titre NHS of BNT162b2 participant Participants Patient Pfizer-BioNTech preserved Primary outcome receive receiving recruited Seven significantly lower single dose South spike glycoprotein spike-specific T-cell response study population the healthy the SARS-CoV-2 therapeutic Therapies Thoma TNF Trust vaccination vaccine immunogenicity Volunteer were excluded white wild-type SARS-CoV-2 [DOI] 10.1016/S2665-9913(21)00212-5 PMC 바로가기 [Article Type] Articles
Eight months follow-up study on pulmonary function, lung radiographic, and related physiological characteristics in COVID-19 survivorsArticle Published on 2021-07-052022-10-04 Journal: Scientific Reports [Category] SARS, 치료법, [키워드] abnormality age analyzed BMI Characteristics clinical collected correlated Course COVID-19 cumulative diffusion discharge Diseases dosage Factors Follow-up follow-up study glucocorticoid greater Health highest Hospitalization IL-8 impairment incidence Infectious diseases Inflammation Inflammatory cytokine LDH lowest lung mild cases outcome Oxygen treatment patients with COVID-19 physiological positively correlated potential risk Pulmonary function Radiographic radiological Respiratory tract diseases serum Severe case severe cases severity of COVID-19 survivor Symptoms three group TNF-α [DOI] 10.1038/s41598-021-93191-y PMC 바로가기 [Article Type] Article
Fitness, strength and severity of COVID-19: a prospective register study of 1 559 187 Swedish conscriptsEpidemiology Published on 2021-07-052022-10-28 Journal: BMJ Open [Category] COVID-19, Fulltext, SARS, [키워드] 95% CI age association baseline blood pressure BMI body mass index cardiorespiratory cardiovascular disease chronic disease cohort study connection COVID-19 CRF death Epidemiology fitness higher risk hospitalisation intensive care linear lowest men Mortality Muscle strength objective offer outcome outcome measure Pandemics parental participant physical physical fitness Prospective Protective public health Result severe COVID-19 severity severity of COVID-19 Swedish [DOI] 10.1136/bmjopen-2021-051316 PMC 바로가기 [Article Type] Epidemiology
Safety of SARS-CoV-2 vaccines: a systematic review and meta-analysis of randomized controlled trialsSARS-CoV-2 백신의 안전성: 무작위 대조 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-07-052022-09-10 Journal: Infectious Diseases of Poverty [Category] 임상, [키워드] 95% CI addition adverse event adverse events Adverse events following immunization approved article candidate clinical trial clinical trials Cochrane Library confidence interval coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine COVID-19 vaccines determine first dose immunization inactivated Inactivated vaccine Local lowest mass vaccination Medical conditions medRxiv Meta-analysis mRNA vaccine no significant differences platform Randomized controlled trial Randomized controlled trials RCT RCTs reported required risk risk ratio risk ratios Safety SARS-CoV-2 second dose significant difference significant differences significantly higher subject supplementary material Surveillance systematic review Tolerance vaccination Vaccine was performed Web of Science [DOI] 10.1186/s40249-021-00878-5 PMC 바로가기 [Article Type] Meta-Analysis
A mixed-methods study describing behavioral factors that influenced general practitioners’ experiences using triage during the COVID-19 pandemicResearch Published on 2021-07-032022-10-28 Journal: BMC Family Practice [Category] Coronavirus, SARS, [키워드] asked calculated conducted Confusion COVID-19 pandemic Digital triage domains examined expand face-to-face contact facilitator Factor framework General practice help highest item lowest median MOST participant Patient patients potential barrier Practical training Practitioner practitioners Quantitative reduce reported response Result risk Satisfaction Study design suggestion supplementary material Support Telephone triage thematic analysis Theoretical domains framework Triage United Kingdom was used [DOI] 10.1186/s12875-021-01469-x PMC 바로가기 [Article Type] Research
Dipeptidylpeptidase-4 levels and DPP4 gene polymorphisms in patients with COVID-19. Association with disease and with severityCOVID-19 환자에서 Dipeptidylpeptidase-4 수준 및 DPP4 유전자 다형성.질병과의 연관성 및 심각성Article Published on 2021-07-012022-08-31 Journal: Life sciences [Category] SARS, 바이오마커, 유전자 메커니즘, 진단, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age Alanine alanine aminotransferase albumin Analysis angiotensin Angiotensin converting enzyme-2 angiotensin-converting enzyme-2 association carrier cause controls coronavirus correlated COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients Dipeptidyl peptidase-4 Dipeptidylpeptidase-4 disease DPP4 enzyme fibrinogen functional Genotype healthy control healthy controls high risk Invasive mechanical ventilation lowest mechanical ventilation Neutrophils not need Patient patients with COVID-19 Platelet polymorphism Polymorphisms quantified receptor reported required respiratory SARS-CoV-2 serum severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity suggested TaqMan assays virus with COVID-19 [DOI] 10.1016/j.lfs.2021.119410 PMC 바로가기 [Article Type] Article