Variability in detection of SARS-CoV-2-specific antibody responses following mild infection: a prospective multicentre cross-sectional study, London, United Kingdom, 17 April to 17 July 2020경증 감염 후 SARS-CoV-2 특이적 항체 반응 검출의 가변성: 전향적 다기관 횡단 연구, 영국 런던, 2020년 4월 17일~7월 17일Multicenter Study Published on 2022-01-272022-09-10 Journal: Eurosurveillance [Category] SARS, 진단, 치료기술, 치료법, 치료제, [키워드] 95% confidence interval Adults age Anosmia anti-RBD Anti-RBD IgG anti-RBD IgG antibodies anti-RBD IgG antibody anti-receptor-binding domain anti-spike antibodies anti-spike antibody antibody Antibody Response Asymptomatic Asymptomatic disease binding confidence interval coronavirus correlated correlation cough COVID-19 cross-sectional cross-sectional study diagnostics expressed Fever IgG IgG antibodies immunoassay immunoassays Linear regression London majority Mild multicentre multivariate neutralising observé PCR-confirmed raise RBD IgG reactivity reported Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody Seroconversion serum sample Sex significantly specific antibodies symptom onset symptomatic symptomatic individuals Symptomatology tested United Kingdom Variability was performed [DOI] 10.2807/1560-7917.ES.2022.27.4.2002076 PMC 바로가기 [Article Type] Multicenter Study
T-Cell Repertoire Characteristics of Asymptomatic and Re-Detectable Positive COVID-19 Patients무증상 및 재검출 가능한 COVID-19 양성 환자의 T-세포 레퍼토리 특성Immunology Published on 2022-01-272022-09-11 Journal: Frontiers in Immunology [Category] 유전자 메커니즘, 치료기술, [키워드] analyzed Asymptomatic asymptomatic patient asymptomatic patients Combination convalescent Convalescent patients courses COVID-19 COVID-19 pandemic COVID-19 patient help immune repertoire sequencing immune response immune responses immunological Immunotherapy positive predict Prevalence re-detectable positive case recurrent infection repertoire risk Surveillance symptomatic T-cell receptor TCR [DOI] 10.3389/fimmu.2021.769442 PMC 바로가기 [Article Type] Immunology
Evaluating the Association Between Comorbidities and COVID-19 Severity Scoring on Chest CT Examinations Between the Two Waves of COVID-19: An Imaging Study Using Artificial IntelligenceRadiology Published on 2022-01-272022-10-31 Journal: Cureus [Category] COVID-19, [키워드] accounted addition Affect affected affecting age Analysis analyzed artificial artificial intelligence bronchial asthma Care Chest Comorbidities Comorbidity Computed tomography concerning Coronavirus disease 2019 COVID-19 COVID-19 pandemic cross-sectional CT chest datasets death demonstrated determine Diabetes Mellitus distribution Evaluating examination female First wave FIVE Gender heterogeneous hypertension IBM imaging institution intelligence males no significant difference not differ Patient performed platform Population positive radiological radiology Result retrospective risk Scoring second wave severity Severity Score SPSS statistically subset symptomatic the disease the mean Tuberculosis USA was performed was used Wave while [DOI] 10.7759/cureus.21656 PMC 바로가기 [Article Type] Radiology
Using Non-Pharmaceutical Interventions and High Isolation of Asymptomatic Carriers to Contain the Spread of SARS-CoV-2 in Nursing HomesArticle Published on 2022-01-262022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] appear attack rate Care carrier Community compartmental model Complete connection COVID-19 death deaths decrease defined effective Endemic Epidemics evaluate First wave home hospitalizations ICU identify include increasingly infections Influenza influenza pandemic Intervention Isolation Local MERS Non-pharmaceutical interventions NPI NPIs Nursing nursing homes Older Outbreaks pandemic parameter pre-symptomatic pre-symptomatic carriers quarantine recorded reduction in SARS-CoV-1 SARS-CoV-2 significantly silent silent transmission susceptible symptomatic the SARS-CoV-2 Transmission [DOI] 10.3390/life12020180 PMC 바로가기 [Article Type] Article
Association of a Third Dose of BNT162b2 Vaccine With Incidence of SARS-CoV-2 Infection Among Health Care Workers in Israel이스라엘의 의료 종사자 중 SARS-CoV-2 감염 발생률이 있는 BNT162b2 백신 3차 접종의 연관성Article Published on 2022-01-252022-09-12 Journal: JAMA [Category] 진단, [키워드] 95% CI adjusted hazard ratio administration age Analysis association Aviv baseline BNT162b2 booster dose conducted Cox regression Cox regression analysis Effectiveness enrolled Enrollment Final Follow-up hazard ratio Health care worker health care workers IgG titer incidence rate individual IQR lower risk median occurred of BNT162b2 Older outcome participant Participants Pfizer-BioNTech Primary outcome prospective cohort study Protein receiving Receptor binding domain reported required SARS-CoV-2 SARS-COV-2 infection Screening significantly significantly lower single center study cohort study enrollment Surveillance symptomatic the median vaccinated individual vaccination Vaccine was performed was used women worker [DOI] 10.1001/jama.2021.23641 PMC 바로가기 [Article Type] Article
High SARS-CoV-2 Prevalence among Healthcare Workers in Cochabamba, Bolivia볼리비아 코차 바바에있는 의료 종사자들 사이의 SARS-COV-2 유병률Article Published on 2022-01-252022-09-01 Journal: Viruses [Category] 진단, 치료기술, [키워드] Ageusia Analysis Anosmia antigenic attack rate Belonging Bolivia Care children Combination conducted Contact contact with COVID-19 COVID-19 treatment cross-sectional determine Dried blood spots ELISA Factors HCW HCWs healthcare worker Healthcare workers household IgG IgG antibodies increased risk medication Multivariate analysis participant PCR potential risk Predictive risk factor Risk factors SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgG antibodies SARS-COV-2 infection SARS-CoV-2 seroprevalence Seropositivity Seroprevalence subject symptomatic the SARS-CoV-2 Treatment with COVID-19 worker [DOI] 10.3390/v14020232 PMC 바로가기 [Article Type] Article
Impaired pulmonary ventilation beyond pneumonia in COVID-19: A preliminary observationCOVID-19에서 폐렴을 넘어 폐환기 장애: 예비 관찰Research Article Published on 2022-01-252022-09-12 Journal: PLoS ONE [Category] 진단, [키워드] abnormality accompanied Accuracy aetiology affected airway Analysis association asymptomatic patient asymptomatic patients baseline characteristic Clinical symptoms comparable coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 pneumonia CT scan CT scans diagnostic Diagnostic accuracy distribution Dyspnea dyspneic Entire lung functional group groups healthy control healthy controls heterogeneity hypoxia identify impair Impaired impairment lung median mild pneumonia nine observation Patient patients patients with COVID-19 pilot study Pneumonia provided Pulmonary function pulmonary ventilation R 2 radiological radiological feature radiological finding receiver receiver operating characteristic Result significantly Symptom symptomatic symptomatic patient Symptomatic patients Symptoms the patient Ventilation was used were assessed worsened [DOI] 10.1371/journal.pone.0263158 PMC 바로가기 [Article Type] Research Article
Duration of viral shedding and culture positivity with postvaccination SARS-CoV-2 delta variant infections백신 접종 후 SARS-CoV-2 델타 변이체 감염으로 인한 바이러스 배출 및 배양 양성 기간Research Article Published on 2022-01-252022-09-10 Journal: JCI Insight [Category] 변종, 치료기술, [키워드] 24 hour 24 hours acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 ambulatory patient ambulatory patients Asymptomatic Breakthrough infection breakthrough infections characterized Cohort collected coronavirus correlated COVID-19 Culture delta variant Duration early stage early stages Epidemiology evaluate greater individual Infection infections Infectious disease initial viral load Isolation likelihood nasal swab nasal swabs PCR PCR positivity postvaccination quantification Replication replication-competent virus resolution of symptoms respiratory SARS-CoV-2 SARS-CoV-2 delta SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 viral load severe acute respiratory syndrome Coronavirus Support symptom onset symptom resolution symptomatic symptomatic individual symptomatic individuals These data US CDC vaccination variant variants Viral viral culture viral load quantification viral shedding virus whole-genome sequencing [DOI] 10.1172/jci.insight.155483 PMC 바로가기 [Article Type] Research Article
Surveillance Web System and Mouthwash-Saliva qPCR for Labor Ambulatory SARS-CoV-2 Detection and Prevention분만 이동 SARS-CoV-2 감지 및 예방을 위한 감시 웹 시스템 및 구강 세척제-타액 qPCRArticle Published on 2022-01-242022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 변종, 치료기술, 치료제, [키워드] Algorithm Alpha Alpha variant ambulatory applied Asymptomatic baseline Community conducted copy number coronavirus COVID-19 database Decision-making detection Detection limit development effective epidemiological epidemiological surveillance Evidence evidence of Follow-up house individual labor Laboratory Mild moderate monitoring Mouthwash N-gene nasopharyngeal swabbing platform populations prevention primer Primers protocol provide provided qPCR RT-qPCR RT-qPCR test Safe SARS-CoV-2 SARS-CoV-2 sequence SARS-CoV-2 sequences SARS-CoV-2 testing sensitivity specificity specimen statistical Surveillance symptomatic symptomatic case System threshold Viral virus virus inactivation volunteers Web work environments [DOI] 10.3390/ijerph19031271 PMC 바로가기 [Article Type] Article
Men are the main COVID-19 transmitters: behavior or biology?Brief Communication Published on 2022-01-242022-11-01 Journal: Discover Mental Health [Category] COVID-19, [키워드] Adult couples affected Analysis Asymptomatic Behavior biological pathway clinical manifestation close contact collected data Combination Contact couple COVID-19 COVID-19 infection COVID-19 susceptibility COVID-19 transmission death epidemiological survey explained Factors Gender genders higher risk household transmission immune response in viral infected individual Infection Measures men Mild not differ outcome performed presence or absence proportion Protective remained Result RT-PCR Saliva SARS-CoV-2 serology Severe case severe COVID-19 Sex difference susceptibility susceptible symptomatic Transmission transmission potential transmission rate vaccination virus was performed were infected women [DOI] 10.1007/s44192-022-00004-3 PMC 바로가기 [Article Type] Brief Communication